The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLR-MYD88 to Autophagic Defense von van der Vaart, Michiel, Korbee, Cornelis J., Lamers, Gerda E.M., Tengeler, Anouk C., Hosseini, Rohola, Haks, Mariëlle C., Ottenhoff, Tom H.M., Spaink, Herman P., Meijer, Annemarie H.

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Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children von Gjøen, John Espen, Jenum, Synne, Sivakumaran, Dhanasekaran, Mukherjee, Aparna, Macaden, Ragini, Kabra, Sushil K., Lodha, Rakesh, Ottenhoff, Tom H. M., Haks, Marielle C., Doherty, Timothy Mark, Ritz, Christian, Grewal, Harleen M. S.

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Host‐directed therapy to combat mycobacterial infections von Kilinç, Gül, Saris, Anno, Ottenhoff, Tom H. M., Haks, Mariëlle C.

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Human Transcriptomic Response to the VSV-Vectored Ebola Vaccine von Santoro, Francesco, Donato, Alessia, Lucchesi, Simone, Sorgi, Sara, Gerlini, Alice, Haks, Marielle C., Ottenhoff, Tom H. M., Gonzalez-Dias, Patricia, Nakaya, Helder, Huttner, Angela, Siegrist, Claire-Anne, Medaglini, Donata, Pozzi, Gianni

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Identification of probable early-onset biomarkers for tuberculosis disease progression von Sutherland, Jayne S, Hill, Philip C, Adetifa, Ifedayo M, de Jong, Bouke C, Donkor, Simon, Joosten, Simone A, Opmeer, Lizet, Haks, Marielle C, Ottenhoff, Tom H M, Adegbola, Richard A, Ota, Martin O C

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Bioorthogonal Correlative Light-Electron Microscopy of Mycobacterium tuberculosis in Macrophages Reveals the Effect of Antituberculosis Drugs on Subcellular Bacterial Distribution von Bakkum, Thomas, Heemskerk, Matthias T, Bos, Erik, Groenewold, Mirjam, Oikonomeas-Koppasis, Nikolaos, Walburg, Kimberley V, van Veen, Suzanne, van der Lienden, Martijn J. C, van Leeuwen, Tyrza, Haks, Marielle C, Ottenhoff, Tom H. M, Koster, Abraham J, van Kasteren, Sander I

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Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represen... von van Meijgaarden, Krista E, Haks, Mariëlle C, Caccamo, Nadia, Dieli, Francesco, Ottenhoff, Tom H M, Joosten, Simone A

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Gene expression profiles classifying clinical stages of tuberculosis and monitoring treatment responses in Ethiopian HIV-negative and HIV-positive cohorts von Gebremicael, Gebremedhin, Kassa, Desta, Alemayehu, Yodit, Gebreegziaxier, Atsbeha, Kassahun, Yonas, van Baarle, Debbie, H M Ottenhoff, Tom, M Cliff, Jacqueline, C Haks, Mariëlle

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An alternative model for type I interferon induction downstream of human TLR2 von Oosenbrug, Timo, van de Graaff, Michel J., Haks, Mariëlle C., van Kasteren, Sander, Ressing, Maaike E.

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Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study von Huttner, Angela, Agnandji, Selidji Todagbe, Combescure, Christophe, Fernandes, José F, Bache, Emmanuel Bache, Kabwende, Lumeka, Ndungu, Francis Maina, Brosnahan, Jessica, Monath, Thomas P, Lemaître, Barbara, Grillet, Stéphane, Botto, Miriam, Engler, Olivier, Portmann, Jasmine, Siegrist, Denise, Bejon, Philip, Silvera, Peter, Kremsner, Peter, Siegrist, Claire-Anne, KRISHNA, Sanjeev, ADDO, Marylyn M., BECKER, Stephan, KRÄHLING, Verena, NJUGUNA, Patricia, KIENY, Marie-Paule, AHMED, Rafi, ANDERSON, Jenna, AUDERSET, Floriane, BORGIANNI, Luisa, CIABATTINI, Annalisa, HAKS, Marielle C., HARANDI, Ali, HEPPNER, Donald Gray, GERLINI, Alice, MEDAGLINI, Donata, OTTENHOFF, Tom H.M., PEJOSKI, David, PAGE, Mark, POZZI, Gianni, SANTORO, Francesco, DUBEY, Sheri, FERNANDES, José F., NAKAYA, Helder, OROURKE, Fiona, ROTHENBERGER, Sylvia

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Whole-blood transcriptomic signatures induced during immunization by chloroquine prophylaxis and Plasmodium falciparum sporozoites von Tran, Tuan M., Bijker, Else M., Haks, Mariëlle C., Ottenhoff, Tom H. M., Visser, Leo, Schats, Remko, Venepally, Pratap, Lorenzi, Hernan, Crompton, Peter D., Sauerwein, Robert W.

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Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials von Korbee, Cornelis J., Heemskerk, Matthias T., Kocev, Dragi, van Strijen, Elisabeth, Rabiee, Omid, Franken, Kees L. M. C., Wilson, Louis, Savage, Nigel D. L., Džeroski, Sašo, Haks, Mariëlle C., Ottenhoff, Tom H. M.

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Blood transcriptional profiles distinguish different clinical stages of cutaneous leishmaniasis in humans von Bahrami, Fariborz, Masoudzadeh, Nasrin, Van Veen, Suzanne, Persson, Josefine, Lari, Arezou, Sarvnaz, Hamzeh, Taslimi, Yasaman, Östensson, Malin, Andersson, Björn, Sharifi, Iraj, Goyonlo, Vahid Mashayekhi, Ottenhoff, Tom HM, Haks, Mariëlle C., Harandi, Ali M., Rafati, Sima

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Repurposing Tamoxifen as Potential Host-Directed Therapeutic for Tuberculosis von Boland, Ralf, Heemskerk, Matthias T, Forn-Cuní, Gabriel, Korbee, Cornelis J, Walburg, Kimberley V, Esselink, Jeroen J, Carvalho Dos Santos, Carina, de Waal, Amy M, van der Hoeven, Daniel C M, van der Sar, Elisa, de Ries, Alex S, Xie, Jiajun, Spaink, Herman P, van der Vaart, Michiel, Haks, Mariëlle C, Meijer, Annemarie H, Ottenhoff, Tom H M

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Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites von Schats, Remko, Bijker, Else M, van Gemert, Geert-Jan, Graumans, Wouter, van de Vegte-Bolmer, Marga, van Lieshout, Lisette, Haks, Mariëlle C, Hermsen, Cornelus C, Scholzen, Anja, Visser, Leo G, Sauerwein, Robert W

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Analyzing the impact of Mycobacterium tuberculosis infection on primary human macrophages by combined exploratory and targeted metabolomics von Vrieling, Frank, Kostidis, Sarantos, Spaink, Herman P., Haks, Mariëlle C., Mayboroda, Oleg A., Ottenhoff, Tom H. M., Joosten, Simone A.

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Functional Inhibition of Host Histone Deacetylases (HDACs) Enhances in vitro and in vivo Anti-mycobacterial Activity in Human Macrophages and in Zebrafish von Moreira, Josimar D., Koch, Bjorn E., van Veen, Suzanne, Walburg, Kimberley, Vrieling, Frank, Dabes Guimaraes, Tania Mara Pinto, Meijer, Annemarie H., Spaink, Herman P., Ottenhoff, Tom H. M., Haks, Marielle C., Heemskerk, Matthias T.

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Impaired Immune Response to Primary but Not to Booster Vaccination Against Hepatitis B in Older Adults von Weinberger, Birgit, Haks, Mariëlle C, de Paus, Roelof A, Ottenhoff, Tom H M, Bauer, Tanja, Grubeck-Loebenstein, Beatrix

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Host Gene Expression Kinetics During Treatment of Tuberculosis in HIV-Coinfected Individuals Is Independent of Highly Active Antiretroviral Therapy von Gebremicael, Gebremedhin, Kassa, Desta, Quinten, Edwin, Alemayehu, Yodit, Gebreegziaxier, Atsbeha, Belay, Yohannes, van Baarle, Debbie, Ottenhoff, Tom H M, Cliff, Jacqueline M, Haks, Mariëlle C

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Stratification of COVID-19 patients based on quantitative immune-related gene expression in whole blood von Persson, Josefine, Andersson, Björn, van Veen, Suzanne, Haks, Mariëlle C., Obudulu, Ogonna, Torkzadeh, Sara, Ottenhoff, Tom H.M., Kanberg, Nelly, Gisslén, Magnus, Andersson, Lars-Magnus, Harandi, Ali M.

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