Human Cardiac Gene Therapy von Ishikawa, Kiyotake, Weber, Thomas, Hajjar, Roger J

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Potential of gene therapy as a treatment for heart failure von Hajjar, Roger J

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Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis von Jeong, Dongtak, PhD, Lee, Min-Ah, MS, Li, Yan, MS, Yang, Dong Kwon, DVM, PhD, Kho, Changwon, PhD, Oh, Jae Gyun, PhD, Hong, Gyeongdeok, BS, Lee, Ahyoung, PhD, Song, Min Ho, BS, LaRocca, Thomas J., MD, PhD, Chen, Jiqiu, MD, Liang, Lifan, MD, Mitsuyama, Shinichi, MD, PhD, D'Escamard, Valentina, PhD, Kovacic, Jason C., MD, PhD, Kwak, Tae Hwan, MS, Hajjar, Roger J., MD, Park, Woo Jin, PhD

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Extracellular Vesicle-Encapsulated Adeno-Associated Viruses for Therapeutic Gene Delivery to the Heart von Li, Xisheng, La Salvia, Sabrina, Liang, Yaxuan, Adamiak, Marta, Kohlbrenner, Erik, Jeong, Dongtak, Chepurko, Elena, Ceholski, Delaine, Lopez-Gordo, Estrella, Yoon, Seonghun, Mathiyalagan, Prabhu, Agarwal, Neha, Jha, Divya, Lodha, Shweta, Daaboul, George, Phan, Anh, Raisinghani, Nikhil, Zhang, Shihong, Zangi, Lior, Gonzalez-Kozlova, Edgar, Dubois, Nicole, Dogra, Navneet, Hajjar, Roger J, Sahoo, Susmita

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Gene Therapy for Heart Failure von Tilemann, Lisa, Ishikawa, Kiyotake, Weber, Thomas, Hajjar, Roger J

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Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes von Fu, Ji-Dong, Rushing, Stephanie N, Lieu, Deborah K, Chan, Camie W, Kong, Chi-Wing, Geng, Lin, Wilson, Kitchener D, Chiamvimonvat, Nipavan, Boheler, Kenneth R, Wu, Joseph C, Keller, Gordon, Hajjar, Roger J, Li, Ronald A

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Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca2+-ATPase in Heart Failure von Gorski, Przemek A, Jang, Seung Pil, Jeong, Dongtak, Lee, Ahyoung, Lee, Philyoung, Oh, Jae Gyun, Chepurko, Vadim, Yang, Dong Kwon, Kwak, Tae Hwan, Eom, Soo Hyun, Park, Zee-Yong, Yoo, Yung Joon, Kim, Do Han, Kook, Hyun, Sunagawa, Yoichi, Morimoto, Tatsuya, Hasegawa, Koji, Sadoshima, Junichi, Hajjar, Roger J, Park, Woo Jin, Kho, Changwon

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Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure von Kho, Changwon, Lee, Ahyoung, Jeong, Dongtak, Oh, Jae Gyun, Gorski, Przemek A., Fish, Kenneth, Sanchez, Roberto, DeVita, Robert J., Christensen, Geir, Dahl, Russell, Hajjar, Roger J.

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miR-146a Suppresses SUMO1 Expression and Induces Cardiac Dysfunction in Maladaptive Hypertrophy von Oh, Jae Gyun, Watanabe, Shin, Lee, Ahyoung, Gorski, Przemek A, Lee, Philyoung, Jeong, Dongtak, Liang, Lifan, Liang, Yaxuan, Baccarini, Alessia, Sahoo, Susmita, Brown, Brian D, Hajjar, Roger J, Kho, Changwon

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Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling von Mayourian, Joshua, Ceholski, Delaine K, Gonzalez, David M, Cashman, Timothy J, Sahoo, Susmita, Hajjar, Roger J, Costa, Kevin D

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Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies von Ramos-Kuri, Manuel, Meka, Sri Harika, Salamanca-Buentello, Fabio, Hajjar, Roger J., Lipskaia, Larissa, Chemaly, Elie R.

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Neutralizing Antibodies Against AAV Serotypes 1, 2, 6, and 9 in Sera of Commonly Used Animal Models von Rapti, Kleopatra, Louis-Jeune, Vedell, Kohlbrenner, Erik, Ishikawa, Kiyotake, Ladage, Dennis, Zolotukhin, Sergei, Hajjar, Roger J, Weber, Thomas

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Myocardial Delivery of Lipidoid Nanoparticle Carrying modRNA Induces Rapid and Transient Expression von Turnbull, Irene C, Eltoukhy, Ahmed A, Fish, Kenneth M, Nonnenmacher, Mathieu, Ishikawa, Kiyotake, Chen, Jiqiu, Hajjar, Roger J, Anderson, Daniel G, Costa, Kevin D

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Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair von del Monte, Federica, Hajjar, Roger J, Lebeche, Djamel, Kühn, Bernhard, Keating, Mark T, Arab, Shima, Chang, Yuh-Shin

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Reversal of Cardiac Dysfunction After Long-Term Expression of SERCA2a by Gene Transfer in a Pre-Clinical Model of Heart Failure von Kawase, Yoshiaki, MD, Ly, Hung Q., MD, MSc, Prunier, Fabrice, MD, PhD, Lebeche, Djamel, PhD, Shi, Yanfen, MD, Jin, Hongwei, PhD, Hadri, Lahouaria, PhD, Yoneyama, Ryuichi, MD, PhD, Hoshino, Kozo, MD, Takewa, Yoshiaki, MD, PhD, Sakata, Susumu, PhD, Peluso, Richard, PhD, Zsebo, Krisztina, PhD, Gwathmey, Judith K., VMD, PhD, Tardif, Jean-Claude, MD, Tanguay, Jean-François, MD, Hajjar, Roger J., MD

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Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle von Goonasekera, Sanjeewa A, Lam, Chi K, Millay, Douglas P, Sargent, Michelle A, Hajjar, Roger J, Kranias, Evangelia G, Molkentin, Jeffery D

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Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial von Jaski, Brian E., MD, FACC, Jessup, Mariell L., MD, Mancini, Donna M., MD, Cappola, Thomas P., MD, Pauly, Daniel F., MD, PhD, Greenberg, Barry, MD, Borow, Kenneth, MD, Dittrich, Howard, MD, Zsebo, Krisztina M., PhD, Hajjar, Roger J., MD

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Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/I... von Kang, Soojeong, Chemaly, Elie R., Hajjar, Roger J., Lebeche, Djamel

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Pre-existing anti-adeno-associated virus antibodies as a challenge in AAV gene therapy von Louis Jeune, Vedell, Joergensen, Jakob A, Hajjar, Roger J, Weber, Thomas

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Effect of local buckling core plate restraint in buckling restrained braces von Takeuchi, T., Hajjar, J.F., Matsui, R., Nishimoto, K., Aiken, I.D.

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