An Enantioselective, Modular, and General Route to the Cytochalasins: Synthesis of L-696,474 and Cytochalasin B von Haidle, Andrew M., Myers, Andrew G., Nicolaou, Kyriacos C.

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Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer von Chang, Wonsuk, Altman, Michael D, Lesburg, Charles A, Perera, Samanthi A, Piesvaux, Jennifer A, Schroeder, Gottfried K, Wyss, Daniel F, Cemerski, Saso, Chen, Yiping, DiNunzio, Edward, Haidle, Andrew M, Ho, Thu, Kariv, Ilona, Knemeyer, Ian, Kopinja, Johnny E, Lacey, Brian M, Laskey, Jason, Lim, Jongwon, Long, Brian J, Ma, Yanhong, Maddess, Matthew L, Pan, Bo-Sheng, Presland, Jeremy P, Spooner, Edward, Steinhuebel, Dietrich, Truong, Quang, Zhang, Zhibo, Fu, Jianmin, Addona, George H, Northrup, Alan B, Parmee, Emma, Tata, James R, Bennett, David Jonathan, Cumming, Jared N, Siu, Tony, Trotter, B. Wesley

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Building a Culture of Medicinal Chemistry Knowledge Sharing von Beshore, Douglas C, Haidle, Andrew M, Arasappan, Ashok, Lim, Yeon-Hee, Raheem, Izzat, Roecker, Anthony J, Shockley, Samantha E, Simov, Vladimir

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Efficacious intermittent dosing of a novel JAK2 inhibitor in mouse models of polycythemia vera von Kraus, Manfred, Wang, Yuxun, Aleksandrowicz, Dan, Bachman, Eric, Szewczak, Alexander A, Walker, Deborah, Xu, Lin, Bouthillette, Melaney, Childers, Kaleen M, Dolinski, Brian, Haidle, Andrew M, Kopinja, Johnny, Lee, Linda, Lim, Jongwon, Little, Kevin D, Ma, Yanhong, Mathur, Anjili, Mo, Jan-Rung, O'Hare, Erin, Otte, Ryan D, Taoka, Brandon M, Wang, Wenxian, Yin, Hong, Zabierek, Anna A, Zhang, Weisheng, Zhao, Shuxia, Zhu, Joe, Young, Jonathan R, Marshall, C Gary

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Augmenting Hit Identification by Virtual Screening Techniques in Small Molecule Drug Discovery von Yan, Xin Cindy, Sanders, John M, Gao, Ying-Duo, Tudor, Matthew, Haidle, Andrew M, Klein, Daniel J, Converso, Antonella, Lesburg, Charles A, Zang, Yi, Wood, Harold B

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Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles von Sanders, John M, Beshore, Douglas C, Culberson, J Christopher, Fells, James I, Imbriglio, Jason E, Gunaydin, Hakan, Haidle, Andrew M, Labroli, Marc, Mattioni, Brian E, Sciammetta, Nunzio, Shipe, William D, Sheridan, Robert P, Suen, Linda M, Verras, Andreas, Walji, Abbas, Joshi, Elizabeth M, Bueters, Tjerk

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A one-step, multi-component reaction for the synthesis of fully substituted 5-amino-4-carboxamidthiazoles von Childers, Kaleen K., Haidle, Andrew M., Machacek, Michelle R., Rogers, J. Patrick, Romeo, Eric

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Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles: Miniperspective von Sanders, John M, Beshore, Douglas C, Culberson, J. Christopher, Fells, James I, Imbriglio, Jason E, Gunaydin, Hakan, Haidle, Andrew M, Labroli, Marc, Mattioni, Brian E, Sciammetta, Nunzio, Shipe, William D, Sheridan, Robert P, Suen, Linda M, Verras, Andreas, Walji, Abbas, Joshi, Elizabeth M, Bueters, Tjerk

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Overcoming Mutagenicity and Ion Channel Activity: Optimization of Selective Spleen Tyrosine Kinase Inhibitors von Ellis, J. Michael, Altman, Michael D, Bass, Alan, Butcher, John W, Byford, Alan J, Donofrio, Anthony, Galloway, Sheila, Haidle, Andrew M, Jewell, James, Kelly, Nancy, Leccese, Erica K, Lee, Sandra, Maddess, Matthew, Miller, J. Richard, Moy, Lily Y, Osimboni, Ekundayo, Otte, Ryan D, Reddy, M. Vijay, Spencer, Kerrie, Sun, Binyuan, Vincent, Stella H, Ward, Gwendolyn J, Woo, Grace H. C, Yang, Chiming, Houshyar, Hani, Northrup, Alan B

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MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentation von Haidle, Andrew M., Childers, Kaleen K., Zabierek, Anna A., Katz, Jason D., Jewell, James P., Hou, Yongquan, Altman, Michael D., Szewczak, Alexander, Chen, Dapeng, Harsch, Andreas, Hayashi, Mansuo, Warren, Lee, Hutton, Michael, Nuthall, Hugh, Stanton, Matt G., Davies, Ian W., Munoz, Ben, Northrup, Alan

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Carboxamide Spleen Tyrosine Kinase (Syk) Inhibitors: Leveraging Ground State Interactions To Accelerate Optimization von Ellis, J. Michael, Altman, Michael D, Cash, Brandon, Haidle, Andrew M, Kubiak, Rachel L, Maddess, Matthew L, Yan, Youwei, Northrup, Alan B

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Thiophene carboxamide inhibitors of JAK2 as potential treatments for myleoproliferative neoplasms von Haidle, Andrew M, Zabierek, Anna A, Childers, Kaleen K, Rosenstein, Craig, Mathur, Anjili, Altman, Michael D, Chan, Grace, Xu, Lin, Bachman, Eric, Mo, Jan-Rung, Bouthillette, Melaney, Rush, Thomas, Tempest, Paul, Marshall, C Gary, Young, Jonathan R

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A practical, two-step synthesis of 1-alkyl-4-aminopyrazoles von Zabierek, Anna A., Konrad, Kaleen M., Haidle, Andrew M.

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ChemInform Abstract: A One-Pot, Multi-Component Reaction for the Synthesis of Fully Substituted 5-Amino-4-carboxamide-thiazoles von Childers, Kaleen K., Haidle, Andrew M., Machacek, Michelle R., Rogers, J. Patrick, Romeo, Eric

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Insulin delivery systems, methods, and devices von HAIDLE ANDREW M

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Preparing N, Napos (N, Napos); method for preparing 2-bis (2, 2, 6, 6-tetramethylpiperidine-4-yl)-1, 6-hexamethylenediamine von HAIDLE ANDREW M, CAPITO, ELENA, SCHMIDT MICHAEL

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IL4I1 INHIBITORS AND METHODS OF USE von Hopkins, Brett A, Liu, Ping, Giambasu, George Madalin, Kaplan, William P, Ferguson, II, Ronald Dale, Zheng, Xiao Mei, Pasternak, Alexander, Candito, David A, Donofrio, Anthony, Lux, Michaelyn C, Yu, Elsie C, Gulati, Anmol, Haidle, Andrew M, Otte, Ryan D

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IL4I1 INHIBITORS AND METHODS OF USE von HOPKINS, BRETT A, CASH, BRANDON D, LIU, PING, YAN, XIN, LARSEN, MATTHEW A, QUIROZ, RYAN, WHITE, CATHERINE M, HAIDLE, ANDREW M, ZHENG, XIAO MEI, SANYAL, SULAGNA, GIAMBASU, GEORGE MADALIN, LESBURG, CHARLES A

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IL4I1 INHIBITORS AND METHODS OF USE von YAN, Xin, HAIDLE, Andrew M, LESBURG, Charles A, MCGOWAN, Meredeth A, FU, Wenlang, LARSEN, Matthew A, GIAMBASU, George Madalin, SILIPHAIVANH, Phieng, SANYAL, Sulagna, WHITE, Catherine M, CASH, Brandon D, PU, Qinglin, HOPKINS, Brett A, LIU, Ping

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Amphoteric modified trialkylene tetramine ethoxylates for improved laundry detergent stain removal von HAIDLE ANDREW M, ENGERT STEPHEN C, TUERK HOLGER

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