Emerging roles for the non-canonical IKKs in cancer von Shen, R R, Hahn, W C

Volltext

PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling von Moody, S E, Schinzel, A C, Singh, S, Izzo, F, Strickland, M R, Luo, L, Thomas, S R, Boehm, J S, Kim, S Y, Wang, Z C, Hahn, W C

Volltext

TERT promotes cellular and organismal survival independently of telomerase activity von Lee, J, Sung, Y H, Cheong, C, Choi, Y S, Jeon, H K, Sun, W, Hahn, W C, Ishikawa, F, Lee, H-W

Volltext

An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer von Sulahian, R, Casey, F, Shen, J, Qian, Z R, Shin, H, Ogino, S, Weir, B A, Vazquez, F, Liu, X S, Hahn, W C, Bass, A J, Chan, V, Shivdasani, R A

Volltext

TRAF2 is an NF-κB-activating oncogene in epithelial cancers von Shen, R R, Zhou, A Y, Kim, E, O'Connell, J T, Hagerstrand, D, Beroukhim, R, Hahn, W C

Volltext

TERT promoter mutations and monoallelic activation of TERT in cancer von Huang, F W, Bielski, C M, Rinne, M L, Hahn, W C, Sellers, W R, Stegmeier, F, Garraway, L A, Kryukov, G V

Volltext

Creation of human tumour cells with defined genetic elements von Weinberg, Robert A, Hahn, William C, Counter, Christopher M, Lundberg, Ante S, Beijersbergen, Roderick L, Brooks, Mary W

Volltext

Lentivirus-delivered stable gene silencing by RNAi in primary cells von Stewart, Sheila A, Dykxhoorn, Derek M, Palliser, Deborah, Mizuno, Hana, Yu, Evan Y, An, Dong Sung, Sabatini, David M, Chen, Irvin S Y, Hahn, William C, Sharp, Phillip A, Weinberg, Robert A, Novina, Carl D

Volltext

PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling von Shrestha, Y, Schafer, E J, Boehm, J S, Thomas, S R, He, F, Du, J, Wang, S, Barretina, J, Weir, B A, Zhao, J J, Polyak, K, Golub, T R, Beroukhim, R, Hahn, W C

Volltext

Mitogen Stimulation Cooperates with Telomere Shortening To Activate DNA Damage Responses and Senescence Signaling von Satyanarayana, A., Greenberg, R. A., Schaetzlein, S., Buer, J., Masutomi, K., Hahn, W. C., Zimmermann, S., Martens, U., Manns, M. P., Rudolph, K. L.

Volltext

Telomerase activation, cellular immortalization and cancer von Hahn, William C, Meyerson, Matthew

Volltext

Modelling the molecular circuitry of cancer von Hahn, William C, Weinberg, Robert A

Volltext

Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells von Dolma, Sonam, Lessnick, Stephen L, Hahn, William C, Stockwell, Brent R

Volltext

Involvement of PP2A in viral and cellular transformation von Arroyo, Jason D, Hahn, William C

Volltext

Telomerase Maintains Telomere Structure in Normal Human Cells von Masutomi, Kenkichi, Yu, Evan Y., Khurts, Shilagardy, Ben-Porath, Ittai, Currier, Jennifer L., Metz, Geoffrey B., Brooks, Mary W., Kaneko, Shuichi, Murakami, Seishi, DeCaprio, James A., Weinberg, Robert A., Stewart, Sheila A., Hahn, William C.

Volltext

Identification of specific PP2A complexes involved in human cell transformation von Chen, Wen, Possemato, Richard, Campbell, K.Thirza, Plattner, Courtney A, Pallas, David C, Hahn, William C

Volltext

Enumeration of the Simian Virus 40 Early Region Elements Necessary for Human Cell Transformation von Hahn, William C., Dessain, Scott K., Brooks, Mary W., King, Jessie E., Elenbaas, Brian, Sabatini, David M., DeCaprio, James A., Weinberg, Robert A.

Volltext

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells von Miele, Lucio, Weijzen, Sanne, Rizzo, Paola, Braid, Mike, Vaishnav, Radhika, Jonkheer, Suzanne M, Zlobin, Andrei, Osborne, Barbara A, Gottipati, Sridevi, Aster, Jon C, Hahn, William C, Rudolf, Michael, Siziopikou, Kalliopi, Kast, W. Martin

Volltext

Chemosensitivity linked to p73 function von Irwin, Meredith S, Kondo, Keiichi, Marin, Maria Carmen, Cheng, Lynn S, Hahn, William C, Kaelin, William G

Volltext

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells von Elenbaas, B, Spirio, L, Koerner, F, Fleming, M D, Zimonjic, D B, Donaher, J L, Popescu, N C, Hahn, W C, Weinberg, R A

Volltext