Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples von CLOOS, J, GOEMANS, B. F, CREUTZIG, U, SCHUURHUIS, G. J, ZWAAN, Ch. M, KASPERS, G. J. L, HESS, C. J, VAN OOSTVEEN, J. W, WAISFISZ, Q, CORTHALS, S, DE LANGE, D, BOECKX, N, HÄHLEN, K, REINHARDT, D

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Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia von GOEMANS, B. F, ZWAAN, Ch. M, KASPERS, G. J. L, HEINRICH, M. C, MILLER, M, ZIMMERMANN, M, HARLOW, A, MESHINCHI, S, LOONEN, A. H, HIHLEN, K, REINHARDT, D, CREUTZIG, U

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Janus kinase mutations in the development of acute megakaryoblastic leukemia in children with and without Down's syndrome von KLUSMANN, J. H, REINHARDT, D, HASLE, H, KASPERS, G. J, CREUTZIG, U, HAHLEN, K, VAN DEN HEUVEL-EIBRINK, M. M, ZWAAN, C. M

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Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia von Licht, Jonathan D, Gelb, Bruce D, Jung, Andreas, Fragale, Alessandra, Song, Xiaoling, Buechner, Jochen, Niemeyer, Charlotte M, Tartaglia, Marco, Hählen, Karel, Hasle, Henrik

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Causes of death - other than progressive leukemia - in childhood acute lymphoblastic (ALL) and myeloid leukemia (AML): the Dutch Childhood Oncology Group experience von SLATS, A. M, EGELER, R. M, VAN DER DOES-VAN DEN BERG, A, KORBIJN, C, HÄHLEN, K, KAMPS, W. A, VEERMAN, A. J. P, ZWAAN, C. M

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TEL/AML1 gene fusion is related to in vitro drug sensitivity for L-asparaginase in childhood acute lymphoblastic leukemia von WOERDEN, N. L. R.-V, PIETERS, R, HÄHLEN, K, SCHMIEGELOW, K, JANKA-SCHAUB, G. E, VEERMAN, A. J. P, LOONEN, A. H, HUBEEK, I, VAN DRUNEN, E, BEVERLOO, H. B, SLATER, R. M, HARBOTT, J, SEYFARTH, J, VAN WERING, E. R

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Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitat... von VAN DER VELDEN, V. H. J, WILLEMSE, M. J, VAN DER SCHOOT, C. E, HÄHLEN, K, VAN WERING, E. R, VAN DONGEN, J. J. M

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Large interindividual differences in cellular sensitivity to calicheamicin may influence gemtuzumab ozogamicin response in acute myeloid leukemia von Goemans, B F, Zwaan, C M, Vijverberg, S J H, Loonen, A H, Creutzig, U, Hählen, K, Reinhardt, D, Gibson, B E S, Cloos, J, Kaspers, G J L

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Minimal residual disease levels in bone marrow and peripheral blood are comparable in children with T cell acute lymphoblastic leukemia (ALL), but not in precursor-B-ALL von VAN DER VELDEN, V. H. J, JACOBS, D. C. H, WIJKHUIJS, A. J. M, COMANS-BITTER, W. M, WILLEMSE, M. J, HÄHLEN, K, KAMPS, W. A, VAN WERING, E. R, VAN DONGEN, J. J. M

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Treatment strategy and results in children treated on three Dutch Childhood Oncology Group acute myeloid leukemia trials von Kardos, G, Zwaan, C M, Kaspers, G J L, de-Graaf, S S N, de Bont, E S J M, Postma, A, Bökkerink, J P M, Weening, R S, van der Does-van den Berg, A, van Wering, E R, Korbijn, C, Hählen, K

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Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia von Zwaan, Christian M., Kaspers, Gert-Jan L., Pieters, Rob, Woerden, Nicole L. Ramakers-Van, den Boer, Monique L., Wünsche, Renate, Rottier, Maria M.A., Hählen, Karel, van Wering, Elizabeth R., Janka-Schaub, Gritta E., Creutzig, Ursula, Veerman, Anjo J.P.

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FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance von Zwaan, Christian M., Meshinchi, Soheil, Radich, Jerald P., Veerman, AnjoJ.P., Huismans, Dieuwke R., Munske, Leonhard, Podleschny, Martina, Hählen, Karel, Pieters, Rob, Zimmermann, Martin, Reinhardt, Dirk, Harbott, Jochen, Creutzig, Ursula, Kaspers, GertjanJ.L., Griesinger, Frank

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High cure rate with a moderately intensive treatment regimen in non-high-risk childhood acute lymphoblastic leukemia. Results of protocol ALL VI from the Dutch Childhood Leukemia S... von VEERMAN, A. J. P, HÄHLEN, K, KAMPS, W. A, VAN LEEUWEN, E. F, DE VAAN, G. A. M, SALBU, G, SUCIU, S, VAN WERING, E. R, VAN DER DOES-VAN DEN BERG, A

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Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute lymphoblastic leukemias : alternative PCR targets for detection o... von SZCZEPANSKI, T, BEISHUIZEN, A, PONGERS-WILLEMSE, M. J, HÄHLEN, K, VAN WERING, E. R, WIJKHUIJS, A. J. M, TIBBE, G. J. M, DE BRUIJN, M. A. C, VAN DONGEN, J. J. M

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Gemtuzumab ozogamicin in pediatric CD33-positive acute lymphoblastic leukemia: first clinical experiences and relation with cellular sensitivity to single agent calicheamicin von Zwaan, C M, Reinhardt, D, Jürgens, H, Huismans, D R, Hählen, K, Smith, O P, Biondi, A, van Wering, E R, Feingold, J, Kaspers, G J L

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In Vitro Cellular Drug Resistance in Children With Relapsed/Refractory Acute Lymphoblastic Leukemia von Klumper, Edwin, Pieters, Rob, Veerman, Anjo J.P., Huismans, Dieuwke R., Loonen, Annemarie H., Hahlen, Karel, Kaspers, Gertjan J.L., van Wering, Elisabeth R., Hartmann, Reinhard, Henze, Günter

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A comparison of the in vitro cytotoxicity of daunorubicin and liposomal daunorubicin in pediatric acute leukemia von Goemans, BF, Zwaan, CM, Reinhardt, D, Gibson, BE, Hahlen, K, Kaspers, GJ

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The Baxα:Bcl‐2 ratio modulates the response to dexamethasone in leukaemic cells and is highly variable in childhood acute leukaemia von Salomons, Gajja S., Brady, Hugh J.M., Verwijs‐Janssen, Manon, Van Den Berg, Joop D., Hart, Augustinus A.M., Van Den Berg, Henk, Behrendt, Henk, Hahlen, Karel, Smets, Lou A.

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The complex interplay between the neck and hinge domains in kinesin-1 dimerization and motor activity von Bathe, Friederike, Hahlen, Katrin, Dombi, Renate, Driller, Lucia, Schliwa, Manfred, Woehlke, Guenther

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Extramedullary infiltrates at diagnosis have no prognostic significance in children with acute myeloid leukaemia von BISSCHOP, M. M, REVESZ, T, BIERINGS, M, VAN WEERDEN, J. F, VAN WERING, E. R, HÄHLEN, K, VAN DER DOES-VAN DEN BERG, A

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