Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression von Guscott, M, Bristow, L J, Hadingham, K, Rosahl, T W, Beer, M S, Stanton, J A, Bromidge, F, Owens, A P, Huscroft, I, Myers, J, Rupniak, N M, Patel, S, Whiting, P J, Hutson, P H, Fone, K C, Biello, S M, Kulagowski, J J, McAllister, G

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Role of the beta subunit in determining the pharmacology of human gamma-aminobutyric acid type A receptors von HADINGHAM, K. L, WINGROVE, P. B, WHITING, P. J, WAFFORD, K. A, BAIN, C, KEMP, J. A, PALMER, K. J, WILSON, A. W, WILCOX, A. S, SIKELA, J. M, RAGAN, C. I

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Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice von Sur, C, Wafford, K A, Reynolds, D S, Hadingham, K L, Bromidge, F, Macaulay, A, Collinson, N, O'Meara, G, Howell, O, Newman, R, Myers, J, Atack, J R, Dawson, G R, McKernan, R M, Whiting, P J, Rosahl, T W

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Cloning of cDNA sequences encoding human α2 and α3 γ-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant α1-, α2-, α3-, and... von HADINGHAM, K. L, WINGROVE, P, LE BOURDELLES, B, PALMER, K. J, RAGAN, C. I, WHITING, P. J

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Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors von Hadingham, K L, Garrett, E M, Wafford, K A, Bain, C, Heavens, R P, Sirinathsinghji, D J, Whiting, P J

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Pharmacology of recombinant human GABA A receptor subtypes measured using a novel pH-based high-throughput functional efficacy assay von Simpson, Peter B, Woollacott, Anthony J, Pillai, Gopalan V, Maubach, Karen A, Hadingham, Karen L, Martin, Karine, Choudhury, Hedaythul I, Seabrook, Guy R

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Ethanol, Flunitrazepam, and Pentobarbital Modulation of GABA A Receptors Expressed in Mammalian Cells and Xenopus Oocytes von Harris, R. Adron, Mihic, S. John, Brozowski, Susan, Hadingham, Karen, Whiting, Paul J.

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CypHer 5: a generic approach for measuring the activation and trafficking of G protein-coupled receptors in live cells von Adie, Elaine J, Francis, Michael J, Davies, June, Smith, Lynne, Marenghi, Angela, Hather, Catherine, Hadingham, Karen, Michael, N Paul, Milligan, Graeme, Game, Stephen

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Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha... von Hadingham, K L, Wingrove, P, Le Bourdelles, B, Palmer, K J, Ragan, C I, Whiting, P J

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Identification of amino acid residues responsible for the alpha 5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA sub(A) receptor von Casula, MA, Bromidge, F A, Pillai, G V, Wingrove, P B, Martin, K, Maubach, K, Seabrook, G R, Whiting, P J, Hadingham, K L

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Identification of amino acid residues responsible for the alpha5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA(A) receptor von Casula, M A, Bromidge, F A, Pillai, G V, Wingrove, P B, Martin, K, Maubach, K, Seabrook, G R, Whiting, P J, Hadingham, K L

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Loss of the Major GABA sub(A) Receptor Subtype in the Brain Is Not Lethal in Mice von Sur, C, Wafford, KA, Reynolds, D S, Hadingham, K L, Bromidge, F, Macaulay, A, Collinson, N, O'Meara, G, Howell, O, Newman, R, Myers, J, Atack, J R, Dawson, G R, McKernan, R M

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Ethanol, Flunitrazepam, and Pentobarbital Modulation of GABAA Receptors Expressed in Mammalian Cells and Xenopus Oocytes von Harris, R. Adron, Mihic, S. John, Brozowski, Susan, Hadingham, Karen, Whiting, Paul J.

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Expression and pharmacology of human GABAA receptors containing gamma 3 subunits von Hadingham, K L, Wafford, K A, Thompson, S A, Palmer, K J, Whiting, P J

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alpha Subunit isoform influences GABA sub(A) receptor modulation by propofol von Krasowski, MD, O'Shea, S M, Rick, CEM, Whiting, P J, Hadingham, K L, Czajkowski, C, Harrison, N L

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α Subunit isoform influences GABAA receptor modulation by propofol von KRASOWSKI, M. D, O'SHEA, S. M, RICK, C. E. M, WHITING, P. J, HADINGHAM, K. L, CZAJKOWSKI, C, HARRISON, N. L

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Identification of domains in human recombinant GABA sub(A) receptors that are photoaffinity labelled by [ super(3)H]flunitrazepam and [ super(3)H]Ro15-4513 von Davies, M, Martin, IL, Bateson, AN, Hadingham, K L, Whiting, P J, Dunn, SMJ

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Identification of domains in human recombinant GABAA receptors that are photoaffinity labelled by [3H]flunitrazepam and [3H]Ro15-4513 von Davies, M, Martin, I L, Bateson, A N, Hadingham, K L, Whiting, P J, Dunn, S M

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The influence of the gamma sub(2L) subunit on the modulation of responses to GABA sub(A) receptor activation von Horne, AL, Harkness, P C, Hadingham, K L, Whiting, P, Kemp, JA

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The pharmacology of recombinant GABA sub(A) receptors containing bovine alpha sub(1), beta sub(1), gamma sub(2L) sub-units stably transfected into mouse fibroblast L-cells von Horne, AL, Hadingham, K L, Macaulay, A J, Whiting, P, Kemp, JA

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