Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy von Wagner, Julia M, Hackanson, Björn, Lübbert, Michael, Jung, Manfred

Volltext

A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy von LÜBBERT, Michael, RÜTER, Björn H, GALM, Oliver, BRUGGER, Wolfram, HEIL, Gerhard, HACKANSON, Björn, DESCHLER, Barbara, DÖHNER, Konstanze, HAGEMEIJER, Anne, WIJERMANS, Pierre W, DÖHNER, Hartmut, CLAUS, Rainer, SCHMOOR, Claudia, SCHMID, Mathias, GERMING, Ulrich, KUENDGEN, Andrea, RETHWISCH, Volker, GANSER, Arnold, PLATZBECKER, Uwe

Volltext

First‐line nab‐paclitaxel plus carboplatin for patients with advanced non‐small cell lung cancer: Final results of the NEPTUN study von Dechow, Tobias, Riera‐Knorrenschild, Jorge, Hackanson, Björn, Janssen, Jan, Schulz, Holger, Oppermann, Ursula, Chiabudini, Marco, Weikersthal, Ludwig Fischer, Budweiser, Stephan, Nacke, Axel, Taeuscher, Dagmar, Welslau, Manfred, Potthoff, Karin

Volltext

Alterations in Peripheral Lymphocyte Subsets under Immunochemotherapy in Stage IV SCLC Patients: Th17 Cells as Potential Early Predictive Biomarker for Response von Schmälter, Ann-Kristin, Löhr, Phillip, Konrad, Maik, Waidhauser, Johanna, Arndt, Tim Tobias, Schiele, Stefan, Thoma, Alicia, Hackanson, Björn, Rank, Andreas

Volltext

In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts von Greve, Gabriele, Andrieux, Geoffroy, Schlosser, Pascal, Blagitko-Dorfs, Nadja, Rehman, Usama-Ur, Ma, Tobias, Pfeifer, Dietmar, Heil, Gerhard, Neubauer, Andreas, Krauter, Jürgen, Heuser, Michael, Salih, Helmut R., Döhner, Konstanze, Döhner, Hartmut, Hackanson, Björn, Boerries, Melanie, Lübbert, Michael

Volltext

Molecular Genetic Characterization of Individual Cancer Cells Isolated via Single-Cell Printing von Riba, Julian, Renz, Nathalie, Niemöller, Christoph, Bleul, Sabine, Pfeifer, Dietmar, Stosch, Juliane M, Metzeler, Klaus H, Hackanson, Björn, Lübbert, Michael, Duyster, Justus, Koltay, Peter, Zengerle, Roland, Claus, Rainer, Zimmermann, Stefan, Becker, Heiko

Volltext

Tumor cell heterogeneity in Small Cell Lung Cancer (SCLC): phenotypical and functional differences associated with Epithelial-Mesenchymal Transition (EMT) and DNA methylation chang... von Krohn, Alexander, Ahrens, Theresa, Yalcin, Arzu, Plönes, Till, Wehrle, Julius, Taromi, Sanaz, Wollner, Stefan, Follo, Marie, Brabletz, Thomas, Mani, Sendurai A, Claus, Rainer, Hackanson, Björn, Burger, Meike

Volltext

Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1 von Rosenbauer, Frank, Tenen, Daniel G, Owens, Bronwyn M, Yu, Li, Tumang, Joseph R, Steidl, Ulrich, Kutok, Jeffery L, Clayton, Linda K, Wagner, Katharina, Scheller, Marina, Iwasaki, Hiromi, Liu, Chunhui, Hackanson, Björn, Akashi, Koichi, Leutz, Achim, Rothstein, Thomas L, Plass, Christoph

Volltext

Characterization of dna demethylation effects induced by 5-Aza-2'-deoxycytidine in patients with myelodysplastic syndrome von MUND, Cora, HACKANSON, Björn, STRESEMANN, Carlo, LÜBBERT, Michael, LYKO, Frank

Volltext

Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia von Becker, Heiko, Pfeifer, Dietmar, Ihorst, Gabriele, Pantic, Milena, Wehrle, Julius, Rüter, Björn H., Bullinger, Lars, Hackanson, Björn, Germing, Ulrich, Kuendgen, Andrea, Platzbecker, Uwe, Döhner, Konstanze, Ganser, Arnold, Hagemeijer, Anne, Wijermans, Pierre W., Döhner, Hartmut, Duyster, Justus, Lübbert, Michael

Volltext

Downregulation of Death-Associated Protein Kinase 1 (DAPK1) in Chronic Lymphocytic Leukemia von Raval, Aparna, Tanner, Stephan M., Byrd, John C., Angerman, Elizabeth B., Perko, James D., Chen, Shih-Shih, Hackanson, Björn, Grever, Michael R., Lucas, David M., Matkovic, Jennifer J., Lin, Thomas S., Kipps, Thomas J., Murray, Fiona, Weisenburger, Dennis, Sanger, Warren, Lynch, Jane, Watson, Patrice, Jansen, Mary, Yoshinaga, Yuko, Rosenquist, Richard, de Jong, Pieter J., Coggill, Penny, Beck, Stephan, Lynch, Henry, de la Chapelle, Albert, Plass, Christoph

Volltext

Activity of decitabine combined with all- trans retinoic acid in oligoblastic acute myeloid leukemia: results from a randomized 2x2 phase II trial (DECIDER) von Rummelt, Christoph, Grishina, Olga, Schmoor, Claudia, Crysandt, Martina, Heuser, Michael, Götze, Katharina S, Schlenk, Richard F, Döhner, Konstanze, Salih, Helmut R, Heil, Gerhard, Müller-Tidow, Carsten, Brugger, Wolfram, Kündgen, Andrea, De Wit, Maike, Giagounidis, Aristoteles, Scholl, Sebastian, Neubauer, Andreas, Krauter, Jürgen, Bug, Gesine, Al-Ali, Haifa Kathrin, Wäsch, Ralph, Becker, Heiko, May, Annette M, Duyster, Justus, Hackanson, Björn, Ganser, Arnold, Döhner, Hartmut, Lübbert, Michael

Volltext

Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia von Hackanson, Björn, Bennett, Kristi L, Brena, Romulo M, Jiang, Jinmai, Claus, Rainer, Chen, Shih-Shih, Blagitko-Dorfs, Nadya, Maharry, Katie, Whitman, Susan P, Schmittgen, Thomas D, Lübbert, Michael, Marcucci, Guido, Bloomfield, Clara D, Plass, Christoph

Volltext

Epigenetic Modulation of Tumor Suppressor CCAAT/Enhancer Binding Protein α Activity in Lung Cancer von Tada, Yasuhiro, Brena, Romulo Martin, Hackanson, Björn, Morrison, Carl, Otterson, Gregory A., Plass, Christoph

Volltext

Evaluating the impact of genetic and epigenetic aberrations on survival and response in acute myeloid leukemia patients receiving epigenetic therapy von Hiller, Jan K., Schmoor, Claudia, Gaidzik, Verena I., Schmidt-Salzmann, Charlotte, Yalcin, Arzu, Abdelkarim, Mahmoud, Blagitko-Dorfs, Nadja, Döhner, Konstanze, Bullinger, Lars, Duyster, Justus, Lübbert, Michael, Hackanson, Björn

Volltext

Epigenetic priming of AML blasts for all-trans retinoic acid-induced differentiation by the HDAC class-I selective inhibitor entinostat von Blagitko-Dorfs, Nadja, Jiang, Yi, Duque-Afonso, Jesús, Hiller, Jan, Yalcin, Arzu, Greve, Gabriele, Abdelkarim, Mahmoud, Hackanson, Björn, Lübbert, Michael

Volltext

Quantitative analyses of DAPK1 methylation in AML and MDS von Claus, Rainer, Hackanson, Björn, Poetsch, Anna R., Zucknick, Manuela, Sonnet, Miriam, Blagitko-Dorfs, Nadja, Hiller, Jan, Wilop, Stefan, Brümmendorf, Tim H., Galm, Oliver, Platzbecker, Uwe, Byrd, John C., Döhner, Konstanze, Döhner, Hartmut, Lübbert, Michael, Plass, Christoph

Volltext

First‐line nab‐paclitaxel plus carboplatin for patients with advanced non‐small cell lung cancer: Results of the NEPTUN study von Dechow, Tobias, Riera‐Knorrenschild, Jorge, Hackanson, Björn, Janssen, Jan, Schulz, Holger, Chiabudini, Marco, Fischer von Weikersthal, Ludwig, Budweiser, Stephan, Nacke, Axel, Taeuscher, Dagmar, Welslau, Manfred, Potthoff, Karin

Volltext

Tracing the development of acute myeloid leukemia in CBL syndrome von Becker, Heiko, Yoshida, Kenichi, Blagitko-Dorfs, Nadja, Claus, Rainer, Pantic, Milena, Abdelkarim, Mahmoud, Niemöller, Christoph, Greil, Christine, Hackanson, Björn, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Döhner, Konstanze, Schnittger, Susanne, Henneke, Philipp, Niemeyer, Charlotte M., Flotho, Christian, Pfeifer, Dietmar, Ogawa, Seishi, Lübbert, Michael

Volltext

Tumor suppressor activity of CCAAT/enhancer binding protein α is epigenetically down-regulated in head and neck squamous cell carcinoma von BENNETT, Kristi L, HACKANSON, Björn, SMITH, Laura T, MORRISON, Carl D, LANG, James C, SCHULLER, David E, WEBER, Frank, ENG, Charis, PLASST, Christoph

Volltext