The human milk oligosaccharides 2’-fucosyllactose and 6’-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling von Sodhi, Chhinder P., Wipf, Peter, Yamaguchi, Yukihiro, Fulton, William B., Kovler, Mark, Niño, Diego F., Zhou, Qinjie, Banfield, Emilyn, Werts, Adam D., Ladd, Mitchell R., Buck, Rachael H., Goehring, Karen C., Prindle, Thomas, Wang, Sanxia, Jia, Hongpeng, Lu, Peng, Hackam, David J.

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A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice von Sodhi, Chhinder P, Nguyen, Jenny, Yamaguchi, Yukihiro, Werts, Adam D, Lu, Peng, Ladd, Mitchell R, Fulton, William B, Kovler, Mark L, Wang, Sanxia, Prindle, Jr, Thomas, Zhang, Yong, Lazartigues, Eric D, Holtzman, Michael J, Alcorn, John F, Hackam, David J, Jia, Hongpeng

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Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis von Egan, Charlotte E, Sodhi, Chhinder P, Good, Misty, Lin, Joyce, Jia, Hongpeng, Yamaguchi, Yukihiro, Lu, Peng, Ma, Congrong, Branca, Maria F, Weyandt, Samantha, Fulton, William B, Niño, Diego F, Prindle, Jr, Thomas, Ozolek, John A, Hackam, David J

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Novel role for the innate immune receptor Toll-like receptor 4 (TLR4) in the regulation of the Wnt signaling pathway and photoreceptor apoptosis von Yi, Hyun, Patel, Amit K, Sodhi, Chhinder P, Hackam, David J, Hackam, Abigail S

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Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors von Neal, Matthew D, Jia, Hongpeng, Eyer, Benjamin, Good, Misty, Guerriero, Christopher J, Sodhi, Chhinder P, Afrazi, Amin, Prindle, Jr, Thomas, Ma, Congrong, Branca, Maria, Ozolek, John, Brodsky, Jeffrey L, Wipf, Peter, Hackam, David J

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Necrotizing enterocolitis, gut microbes, and sepsis von Duess, Johannes W., Sampah, Maame E., Lopez, Carla M., Tsuboi, Koichi, Scheese, Daniel J., Sodhi, Chhinder P., Hackam, David J.

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The human milk oligosaccharide 2′-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine von Good, Misty, Sodhi, Chhinder P., Yamaguchi, Yukihiro, Jia, Hongpeng, Lu, Peng, Fulton, William B., Martin, Laura Y., Prindle, Thomas, Nino, Diego F., Zhou, Qinjie, Ma, Congrong, Ozolek, John A., Buck, Rachael H., Goehring, Karen C., Hackam, David J.

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Precision-based modeling approaches for necrotizing enterocolitis von Kovler, Mark L., Sodhi, Chhinder P., Hackam, David J.

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Mucosa-associated bacterial diversity in necrotizing enterocolitis von Brower-Sinning, Rachel, Zhong, Diana, Good, Misty, Firek, Brian, Baker, Robyn, Sodhi, Chhinder P, Hackam, David J, Morowitz, Michael J

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Maternal aryl hydrocarbon receptor activation protects newborns against necrotizing enterocolitis von Lu, Peng, Yamaguchi, Yukihiro, Fulton, William B., Wang, Sanxia, Zhou, Qinjie, Jia, Hongpeng, Kovler, Mark L., Salazar, Andres Gonzalez, Sampah, Maame, Prindle, Thomas, Wipf, Peter, Sodhi, Chhinder P., Hackam, David J.

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Prenatal Immunity and Influences on Necrotizing Enterocolitis and Associated Neonatal Disorders von Sampah, Maame Efua S., Hackam, David J.

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Dysregulated Mucosal Immunity and Associated Pathogeneses in Preterm Neonates von Sampah, Maame Efua S., Hackam, David J.

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The role of epithelial Toll-like receptor signaling in the pathogenesis of intestinal inflammation von Gribar, Steven C., Anand, Rahul J., Sodhi, Chhinder P., Hackam, David J.

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Mechanisms of gut barrier failure in the pathogenesis of necrotizing enterocolitis: Toll-like receptors throw the switch von Hackam, David J., MD, PhD, Good, Misty, MD, Sodhi, Chhinder P., PhD

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Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS–NO–nitrite signaling von Yazji, Ibrahim, Sodhi, Chhinder P., Lee, Elizabeth K., Good, Misty, Egan, Charlotte E., Afrazi, Amin, Neal, Matthew D., Jia, Hongpeng, Lin, Joyce, Ma, Congrong, Branca, Maria F., Prindle, Thomas, Richardson, Ward M., Ozolek, John, Billiar, Timothy R., Binion, David G., Gladwin, Mark T., Hackam, David J.

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A Critical Role for TLR4 in the Pathogenesis of Necrotizing Enterocolitis by Modulating Intestinal Injury and Repair von Leaphart, Cynthia L, Cavallo, Jaime, Gribar, Steven C, Cetin, Selma, Li, Jun, Branca, Maria F, Dubowski, Theresa D, Sodhi, Chhinder P, Hackam, David J

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Toll-like Receptor 4-mediated Endoplasmic Reticulum Stress in Intestinal Crypts Induces Necrotizing Enterocolitis von Afrazi, Amin, Branca, Maria F., Sodhi, Chhinder P., Good, Misty, Yamaguchi, Yukihiro, Egan, Charlotte E., Lu, Peng, Jia, Hongpeng, Shaffiey, Shahab, Lin, Joyce, Ma, Congrong, Vincent, Garrett, Thomas, Prindle, Weyandt, Samantha, Neal, Matthew D., Ozolek, John A., Wiersch, John, Tschurtschenthaler, Markus, Shiota, Chiyo, Gittes, George K., Billiar, Timothy R., Mollen, Kevin, Kaser, Arthur, Blumberg, Richard, Hackam, David J.

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Intestinal Epithelial TLR-4 Activation Is Required for the Development of Acute Lung Injury after Trauma/Hemorrhagic Shock via the Release of HMGB1 from the Gut von Sodhi, Chhinder P, Jia, Hongpeng, Yamaguchi, Yukihiro, Lu, Peng, Good, Misty, Egan, Charlotte, Ozolek, John, Zhu, Xiaorong, Billiar, Timothy R, Hackam, David J

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Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents von Harris, R Adron, Bajo, Michal, Bell, Richard L, Blednov, Yuri A, Varodayan, Florence P, Truitt, Jay M, de Guglielmo, Giordano, Lasek, Amy W, Logrip, Marian L, Vendruscolo, Leandro F, Roberts, Amanda J, Roberts, Edward, George, Olivier, Mayfield, Jody, Billiar, Timothy R, Hackam, David J, Mayfield, R Dayne, Koob, George F, Roberto, Marisa, Homanics, Gregg E

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Xenotransplanted human organoids identify transepithelial zinc transport as a key mediator of intestinal adaptation von Sampah, Maame Efua S., Moore, Hannah, Ahmad, Raheel, Duess, Johannes, Lu, Peng, Lopez, Carla, Steinway, Steve, Scheese, Daniel, Raouf, Zachariah, Tsuboi, Koichi, Ding, Jeffrey, Caputo, Connor, McFarland, Madison, Fulton, William B., Wang, Sanxia, Wang, Meghan, Prindle, Thomas, Gazit, Vered, Rubin, Deborah C., Alaish, Samuel, Sodhi, Chhinder P., Hackam, David J.

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