A Randomized, double-blind, dose ranging clinical trial of intravenous FDY-5301 in acute STEMI patients undergoing primary PCI von Adlam, David, Zarebinski, Maciej, Uren, Neal G., Ptaszynski, Pawel, Oldroyd, Keith G., Munir, Shahzad, Zaman, Azfar, Contractor, Hussain, Kiss, Róbert Gábor, Édes, István, Szachniewicz, Joanna, Nagy, Gergely Gyorgy, Garcia, Mario J., Tomcsanyi, János, Irving, John, Sharp, Andrew S.P., Musialek, Piotr, Lupkovics, Géza, Shirodaria, Cheerag, Selvanayagam, Joseph B., Quinn, Pauline, Ng, Leong, Roth, Mark, Insko, Michael A., Haber, Ben, Hill, Stephen, Siegel, Lori, Tulloch, Simon, Channon, Keith M.

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Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis von Aceto, Nicola, Bardia, Aditya, Miyamoto, David T., Donaldson, Maria C., Wittner, Ben S., Spencer, Joel A., Yu, Min, Pely, Adam, Engstrom, Amanda, Zhu, Huili, Brannigan, Brian W., Kapur, Ravi, Stott, Shannon L., Shioda, Toshi, Ramaswamy, Sridhar, Ting, David T., Lin, Charles P., Toner, Mehmet, Haber, Daniel A., Maheswaran, Shyamala

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Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis von Ebright, Richard Y., Lee, Sooncheol, Wittner, Ben S., Niederhoffer, Kira L., Nicholson, Benjamin T., Bardia, Aditya, Truesdell, Samuel, Wiley, Devon F., Wesley, Benjamin, Li, Selena, Mai, Andy, Aceto, Nicola, Vincent-Jordan, Nicole, Szabolcs, Annamaria, Chirn, Brian, Kreuzer, Johannes, Comaills, Valentine, Kalinich, Mark, Haas, Wilhelm, Ting, David T., Toner, Mehmet, Vasudevan, Shobha, Haber, Daniel A., Maheswaran, Shyamala, Micalizzi, Douglas S.

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RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance von Miyamoto, David T., Zheng, Yu, Wittner, Ben S., Lee, Richard J., Zhu, Huili, Broderick, Katherine T., Desai, Rushil, Fox, Douglas B., Brannigan, Brian W., Trautwein, Julie, Arora, Kshitij S., Desai, Niyati, Dahl, Douglas M., Sequist, Lecia V., Smith, Matthew R., Kapur, Ravi, Wu, Chin-Lee, Shioda, Toshi, Ramaswamy, Sridhar, Ting, David T., Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.

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Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility von Yu, Min, Bardia, Aditya, Aceto, Nicola, Bersani, Francesca, Madden, Marissa W., Donaldson, Maria C., Desai, Rushil, Zhu, Huili, Comaills, Valentine, Zheng, Zongli, Wittner, Ben S., Stojanov, Petar, Brachtel, Elena, Sgroi, Dennis, Kapur, Ravi, Shioda, Toshihiro, Ting, David T., Ramaswamy, Sridhar, Getz, Gad, Iafrate, A. John, Benes, Cyril, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.

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Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition von Yu, Min, Bardia, Aditya, Wittner, Ben S., Stott, Shannon L, Smas, Malgorzata E., Ting, David T., Isakoff, Steven J., Ciciliano, Jordan C., Wells, Marissa N., Shah, Ajay M., Concannon, Kyle F., Donaldson, Maria C., Sequist, Lecia V., Brachtel, Elena, Sgroi, Dennis, Baselga, Jose, Ramaswamy, Sridhar, Toner, Mehmet, Haber, Daniel A., Maheswaran, Shyamala

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Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells von Ting, David T., Wittner, Ben S., Ligorio, Matteo, Vincent Jordan, Nicole, Shah, Ajay M., Miyamoto, David T., Aceto, Nicola, Bersani, Francesca, Brannigan, Brian W., Xega, Kristina, Ciciliano, Jordan C., Zhu, Huili, MacKenzie, Olivia C., Trautwein, Julie, Arora, Kshitij S., Shahid, Mohammad, Ellis, Haley L., Qu, Na, Bardeesy, Nabeel, Rivera, Miguel N., Deshpande, Vikram, Ferrone, Cristina R., Kapur, Ravi, Ramaswamy, Sridhar, Shioda, Toshi, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.

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HIF1A signaling selectively supports proliferation of breast cancer in the brain von Ebright, Richard Y., Zachariah, Marcus A., Micalizzi, Douglas S., Wittner, Ben S., Niederhoffer, Kira L., Nieman, Linda T., Chirn, Brian, Wiley, Devon F., Wesley, Benjamin, Shaw, Brian, Nieblas-Bedolla, Edwin, Atlas, Lian, Szabolcs, Annamaria, Iafrate, Anthony J., Toner, Mehmet, Ting, David T., Brastianos, Priscilla K., Haber, Daniel A., Maheswaran, Shyamala

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Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer von Bersani, Francesca, Lee, Eunjung, Kharchenko, Peter V., Xu, Andrew W., Liu, Mingzhu, Xega, Kristina, MacKenzie, Olivia C., Brannigan, Brian W., Wittner, Ben S., Jung, Hyunchul, Ramaswamy, Sridhar, Park, Peter J., Maheswaran, Shyamala, Ting, David T., Haber, Daniel A.

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Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy von Hong, Xin, Sullivan, Ryan J., Kalinich, Mark, Kwan, Tanya Todorova, Giobbie-Hurder, Anita, Pan, Shiwei, LiCausi, Joseph A., Milner, John D., Nieman, Linda T., Wittner, Ben S., Ho, Uyen, Chen, Tianqi, Kapur, Ravi, Lawrence, Donald P., Flaherty, Keith T., Sequist, Lecia V., Ramaswamy, Sridhar, Miyamoto, David T., Lawrence, Michael, Toner, Mehmet, Isselbacher, Kurt J., Maheswaran, Shyamala, Haber, Daniel A.

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A microfluidic device for label-free, physical capture of circulating tumor cell clusters von Sarioglu, A Fatih, Aceto, Nicola, Kojic, Nikola, Donaldson, Maria C, Zeinali, Mahnaz, Hamza, Bashar, Engstrom, Amanda, Zhu, Huili, Sundaresan, Tilak K, Miyamoto, David T, Luo, Xi, Bardia, Aditya, Wittner, Ben S, Ramaswamy, Sridhar, Shioda, Toshi, Ting, David T, Stott, Shannon L, Kapur, Ravi, Maheswaran, Shyamala, Haber, Daniel A, Toner, Mehmet

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Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination von Zheng, Yu, Miyamoto, David T., Wittner, Ben S., Sullivan, James P., Aceto, Nicola, Jordan, Nicole Vincent, Yu, Min, Karabacak, Nezihi Murat, Comaills, Valentine, Morris, Robert, Desai, Rushil, Desai, Niyati, Emmons, Erin, Milner, John D., Lee, Richard J., Wu, Chin-Lee, Sequist, Lecia V., Haas, Wilhelm, Ting, David T., Toner, Mehmet, Ramaswamy, Sridhar, Maheswaran, Shyamala, Haber, Daniel A.

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A Digital RNA Signature of Circulating Tumor Cells Predicting Early Therapeutic Response in Localized and Metastatic Breast Cancer von Kwan, Tanya T, Bardia, Aditya, Spring, Laura M, Giobbie-Hurder, Anita, Kalinich, Mark, Dubash, Taronish, Sundaresan, Tilak, Hong, Xin, LiCausi, Joseph A, Ho, Uyen, Silva, Erin J, Wittner, Ben S, Sequist, Lecia V, Kapur, Ravi, Miyamoto, David T, Toner, Mehmet, Haber, Daniel A, Maheswaran, Shyamala

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HER2 expression identifies dynamic functional states within circulating breast cancer cells von Jordan, Nicole Vincent, Bardia, Aditya, Wittner, Ben S., Benes, Cyril, Ligorio, Matteo, Zheng, Yu, Yu, Min, Sundaresan, Tilak K., Licausi, Joseph A., Desai, Rushil, O’Keefe, Ryan M., Ebright, Richard Y., Boukhali, Myriam, Sil, Srinjoy, Onozato, Maristela L., Iafrate, Anthony J., Kapur, Ravi, Sgroi, Dennis, Ting, David T., Toner, Mehmet, Ramaswamy, Sridhar, Haas, Wilhelm, Maheswaran, Shyamala, Haber, Daniel A.

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Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1 von Javaid, Sarah, Zhang, Jianmin, Anderssen, Endre, Black, Josh C., Wittner, Ben S., Tajima, Ken, Ting, David T., Smolen, Gromoslaw A., Zubrowski, Matthew, Desai, Rushil, Maheswaran, Shyamala, Ramaswamy, Sridhar, Whetstine, Johnathan R., Haber, Daniel A.

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TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state von Matsuda, Satoru, Revandkar, Ajinkya, Dubash, Taronish D., Ravi, Arvind, Wittner, Ben S., Lin, Maoxuan, Morris, Robert, Burr, Risa, Guo, Hongshan, Seeger, Karsen, Szabolcs, Annamaria, Che, Dante, Nieman, Linda, Getz, Gad A., Ting, David T., Lawrence, Michael S., Gainor, Justin, Haber, Daniel A., Maheswaran, Shyamala

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Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer von Miyamoto, David T, Lee, Richard J, Stott, Shannon L, Ting, David T, Wittner, Ben S, Ulman, Matthew, Smas, Malgorzata E, Lord, Jenna B, Brannigan, Brian W, Trautwein, Julie, Bander, Neil H, Wu, Chin-Lee, Sequist, Lecia V, Smith, Matthew R, Ramaswamy, Sridhar, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A

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Isolation and Molecular Characterization of Circulating Melanoma Cells von Luo, Xi, Mitra, Devarati, Sullivan, Ryan J., Wittner, Ben S., Kimura, Anya M., Pan, Shiwei, Hoang, Mai P., Brannigan, Brian W., Lawrence, Donald P., Flaherty, Keith T., Sequist, Lecia V., McMahon, Martin, Bosenberg, Marcus W., Stott, Shannon L., Ting, David T., Ramaswamy, Sridhar, Toner, Mehmet, Fisher, David E., Maheswaran, Shyamala, Haber, Daniel A.

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The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis von Hong, Xin, Roh, Whijae, Sullivan, Ryan J., Wong, Keith H. K., Wittner, Ben S., Guo, Hongshan, Dubash, Taronish D., Sade-Feldman, Moshe, Wesley, Benjamin, Horwitz, Elad, Boland, Genevieve M., Marvin, Dieuwke L., Bonesteel, Todd, Lu, Chenyue, Aguet, Francois, Burr, Risa, Freeman, Samuel S., Parida, Laxmi, Calhoun, Katherine, Jewett, Michelle K., Nieman, Linda T., Hacohen, Nir, Naar, Anders M., Ting, David T., Toner, Mehmet, Stott, Shannon L., Getz, Gad, Maheswaran, Shyamala, Haber, Daniel A.

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RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis von Yu, Min, Ting, David T., Stott, Shannon L., Wittner, Ben S., Ozsolak, Fatih, Paul, Suchismita, Ciciliano, Jordan C., Smas, Malgorzata E., Winokur, Daniel, Gilman, Anna J., Ulman, Matthew J., Xega, Kristina, Contino, Gianmarco, Alagesan, Brinda, Brannigan, Brian W., Milos, Patrice M., Ryan, David P., Sequist, Lecia V., Bardeesy, Nabeel, Ramaswamy, Sridhar, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.

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