Kinase activities in pancreatic ductal adenocarcinoma with prognostic and therapeutic avenues von Vallés‐Martí, Andrea, Goeij‐de Haas, Richard R., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Knol, Jaco C., Verheij, Joanne, Dijk, Frederike, Halfwerk, Hans, Giovannetti, Elisa, Jiménez, Connie R., Bijlsma, Maarten F.

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Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling von Verweij, Frederik Johannes, Bebelman, Maarten P, Jimenez, Connie R, Garcia-Vallejo, Juan J, Janssen, Hans, Neefjes, Jacques, Knol, Jaco C, de Goeij-de Haas, Richard, Piersma, Sander R, Baglio, S Rubina, Verhage, Matthijs, Middeldorp, Jaap M, Zomer, Anoek, van Rheenen, Jacco, Coppolino, Marc G, Hurbain, Ilse, Raposo, Graça, Smit, Martine J, Toonen, Ruud F G, van Niel, Guillaume, Pegtel, D Michiel

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Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies von Cordo’, Valentina, Meijer, Mariska T., Hagelaar, Rico, de Goeij-de Haas, Richard R., Poort, Vera M., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Oshima, Koichi, Ferrando, Adolfo A., Zaman, Guido J. R., Jimenez, Connie R., Meijerink, Jules P. P.

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Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma von Vallés-Martí, Andrea, Mantini, Giulia, Manoukian, Paul, Waasdorp, Cynthia, Sarasqueta, Arantza Fariña, de Goeij-de Haas, Richard R., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Knol, Jaco C., Giovannetti, Elisa, Bijlsma, Maarten F., Jiménez, Connie R.

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Phosphoproteomics After Guanidinium Thiocyanate Extraction of Tissue Biopsies von Rolfs, Frank, de Goeij-de Haas, Richard R., Knol, Jaco C., Piersma, Sander R., Jimenez, Connie R.

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INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases von Beekhof, Robin, van Alphen, Carolien, Henneman, Alex A, Knol, Jaco C, Pham, Thang V, Rolfs, Frank, Labots, Mariette, Henneberry, Evan, Le Large, Tessa YS, de Haas, Richard R, Piersma, Sander R, Vurchio, Valentina, Bertotti, Andrea, Trusolino, Livio, Verheul, Henk MW, Jimenez, Connie R

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Human Testis Phosphoproteome Reveals Kinases as Potential Targets in Spermatogenesis and Testicular Cancer von Castillo, Judit, Knol, Jaco C., Korver, Cindy M., Piersma, Sander R., Pham, Thang V., de Goeij-de Haas, Richard R., van Pelt, Ans M.M., Jimenez, Connie R., Jansen, Bastiaan J.H.

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Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3-Linked Sialic Acid Ligand Binding von Li, Rui-Jún Eveline, de Haas, Aram, Rodríguez, Ernesto, Kalay, Hakan, Zaal, Anouk, Jimenez, Connie R, Piersma, Sander R, Pham, Thang V, Henneman, Alex A, de Goeij-de Haas, Richard R, van Vliet, Sandra J, van Kooyk, Yvette

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Selective targeting of ligand-dependent and -independent signaling by GPCR conformation-specific anti-US28 intrabodies von De Groof, Timo W. M., Bergkamp, Nick D., Heukers, Raimond, Giap, Truc, Bebelman, Maarten P., Goeij-de Haas, Richard, Piersma, Sander R., Jimenez, Connie R., Garcia, K. Christopher, Ploegh, Hidde L., Siderius, Marco, Smit, Martine J.

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Phosphotyrosine-based-phosphoproteomics scaled-down to biopsy level for analysis of individual tumor biology and treatment selection von Labots, Mariette, van der Mijn, Johannes C., Beekhof, Robin, Piersma, Sander R., de Goeij-de Haas, Richard R., Pham, Thang V., Knol, Jaco C., Dekker, Henk, van Grieken, Nicole C.T., Verheul, Henk M.W., Jiménez, Connie R.

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Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers von Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., Jonkers, Jos

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Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance von GOTINK, Kristy J, BROXTERMAN, Henk J, GRIFFIOEN, Arjan W, ASSARAF, Yehuda G, PILI, Roberto, PETERS, Godefridus J, VERHEUL, Henk M. W, LABOTS, Mariette, DE HAAS, Richard R, DEKKER, Henk, HONEYWELL, Richard J, RUDEK, Michelle A, BEEREPOOT, Laurens V, MUSTERS, René J, JANSEN, Gerrit

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Truncated FGFR2 is a clinically actionable oncogene in multiple cancers von Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., Jonkers, Jos

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Phosphoproteomic Analysis of FLCN Inactivation Highlights Differential Kinase Pathways and Regulatory TFEB Phosphoserines von Glykofridis, Iris E., Henneman, Alex A., Balk, Jesper A., Goeij-de Haas, Richard, Westland, Denise, Piersma, Sander R., Knol, Jaco C., Pham, Thang V., Boekhout, Michiel, Zwartkruis, Fried J.T., Wolthuis, Rob M.F., Jimenez, Connie R.

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Sunitinib activates Axl signaling in renal cell cancer von van der Mijn, Johannes C., Broxterman, Henk J., Knol, Jaco C., Piersma, Sander R., De Haas, Richard R., Dekker, Henk, Pham, Thang V., Van Beusechem, Victor W., Halmos, Balazs, Mier, James W., Jiménez, Connie R., Verheul, Henk M.W.

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Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients von Buffart, Tineke E, van den Oord, Rosanne A H M, van den Berg, Adriënne, Hilhorst, Riet, Bastiaensen, Niek, Pruijt, Hans F M, van den Brule, Adriaan, Nooijen, Peet, Labots, Mariette, de Goeij-de Haas, Richard R, Dekker, Henk, Piersma, Sander R, Pham, Thang V, van der Leij, Theo, de Wijn, Rik, Ruijtenbeek, Rob, Jiménez, Connie R, Verheul, Henk M W

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Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib von Gotink, Kristy J., Rovithi, Maria, de Haas, Richard R., Honeywell, Richard J., Dekker, Henk, Poel, Dennis, Azijli, Kaamar, Peters, Godefridus J., Broxterman, Henk J., Verheul, Henk M. W.

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AAMP and MTSS1 Are Novel Negative Regulators of Endothelial Barrier Function Identified in a Proteomics Screen von Podieh, Fabienne, Overboom, Max C, Knol, Jaco C, Piersma, Sander R, Goeij-de Haas, Richard, Pham, Thang V, Jimenez, Connie R, Hordijk, Peter L

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VRK1 Regulates Sensitivity to Oxidative Stress by Altering Histone Epigenetic Modifications and the Nuclear Phosphoproteome in Tumor Cells von Navarro-Carrasco, Elena, Monte-Serrano, Eva, Campos-Díaz, Aurora, Rolfs, Frank, de Goeij-de Haas, Richard, Pham, Thang V, Piersma, Sander R, González-Alonso, Paula, Jiménez, Connie R, Lazo, Pedro A

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IGF1R signaling induces epithelial-mesenchymal plasticity via ITGAV in cutaneous carcinoma von Lopez-Cerda, Marta, Lorenzo-Sanz, Laura, da Silva-Diz, Victoria, Llop, Sandra, Penin, Rosa M, Bermejo, Josep Oriol, de Goeij-de Haas, Richard, Piersma, Sander R, Pham, Thang V, Jimenez, Connie R, Martin-Liberal, Juan, Muñoz, Purificación

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