The European Medicines Agency Review of pitolisant for treatment of narcolepsy: summary of the scientific assessment by the Committee for Medicinal Products for Human Use von Kollb-Sielecka, Marta, Demolis, Pierre, Emmerich, Joseph, Markey, Greg, Salmonson, Tomas, Haas, Manuel

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Stakeholder cooperation to overcome challenges in orphan medicine development: the example of Duchenne muscular dystrophy von Straub, Volker, MD, Balabanov, Pavel, PhD, Bushby, Kate, MD, Ensini, Monica, PhD, Goemans, Nathalie, MD, De Luca, Annamaria, PhD, Pereda, Alejandra, Hemmings, Robert, Campion, Giles, MD, Kaye, Edward, MD, Arechavala-Gomeza, Virginia, PhD, Goyenvalle, Aurelie, PhD, Niks, Erik, MD, Veldhuizen, Olav, Furlong, Pat, Stoyanova-Beninska, Violeta, MD, Wood, Matthew J, PhD, Johnson, Alex, Mercuri, Eugenio, MD, Muntoni, Francesco, MD, Sepodes, Bruno, PhD, Haas, Manuel, PharmD, Vroom, Elizabeth, DMD, Aartsma-Rus, Annemieke, Dr

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Development of Exon Skipping Therapies for Duchenne Muscular Dystrophy: A Critical Review and a Perspective on the Outstanding Issues von Aartsma-Rus, Annemieke, Straub, Volker, Hemmings, Robert, Haas, Manuel, Schlosser-Weber, Gabriele, Stoyanova-Beninska, Violeta, Mercuri, Eugenio, Muntoni, Francesco, Sepodes, Bruno, Vroom, Elizabeth, Balabanov, Pavel

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Experimental investigation on entrainment in two-phase free jets von Hotz, Christian, Haas, Manuel, Wachter, Simon, Fleck, Sabine, Kolb, Thomas

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Entrained flow gasification: Impact of fuel spray distribution on reaction zone structure von Haas, Manuel, Dammann, Maximilian, Fleck, Sabine, Kolb, Thomas

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Two-phase free jet model of an atmospheric entrained flow gasifier von Hotz, Christian, Haas, Manuel, Wachter, Simon, Fleck, Sabine, Kolb, Thomas

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Insights into the catalytic CO2 methanation of a boiling water cooled fixed-bed reactor: Simulation-based analysis von Gruber, Manuel, Wiedmann, Denis, Haas, Manuel, Harth, Stefan, Loukou, Alexandra, Trimis, Dimosthenis

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Development of Exon Skipping Therapies for Duchenne Muscular Dystrophy: A Critical Review and a Perspective on the Outstanding Issues von Aartsma-Rus, Annemieke, Straub, Volker, Hemmings, Robert, Haas, Manuel, Schlosser-Weber, Gabriele, Stoyanova-Beninska, Violeta, Mercuri, Eugenio, Muntoni, Francesco, Sepodes, Bruno, Vroom, Elizabeth, Balabanov, Pavel

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Challenges in drug development for central nervous system disorders: a European Medicines Agency perspective von Butlen-Ducuing, Florence, Pétavy, Frank, Guizzaro, Lorenzo, Zienowicz, Malgorzata, Salmonson, Tomas, Haas, Manuel, Corruble, Emmanuelle, Alteri, Enrica

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Potency ranking of pyrrolizidine alkaloids in metabolically competent human liver cancer cells and primary human hepatocytes using a genotoxicity test battery von Haas, Manuel, Wirachowski, Karina, Thibol, Lea, Küpper, Jan-Heiner, Schrenk, Dieter, Fahrer, Jörg

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Effects of sustainable forest management on tree diversity, timber volumes, and carbon stocks in an ecotone forest in the northern Brazilian Amazon von Condé, Tiago Monteiro, Tonini, Helio, Higuchi, Niro, Higuchi, Francisco Gasparetto, Lima, Adriano José Nogueira, Barbosa, Reinaldo Imbrozio, dos Santos Pereira, Taiguara, Haas, Manuel Alexander

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OCT1-dependent uptake of structurally diverse pyrrolizidine alkaloids in human liver cells is crucial for their genotoxic and cytotoxic effects von Haas, Manuel, Ackermann, Gabriel, Küpper, Jan-Heiner, Glatt, Hansruedi, Schrenk, Dieter, Fahrer, Jörg

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Regulatory watch: Challenges in drug development for central nervous system disorders: a European Medicines Agency perspective von Butlen-Ducuing, Florence, Pétavy, Frank, Guizzaro, Lorenzo, Zienowicz, Malgorzata, Haas, Manuel, Alteri, Enrica, Salmonson, Tomas, Corruble, Emmanuelle

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European Medicines Agency review of ataluren for the treatment of ambulant patients aged 5 years and older with Duchenne muscular dystrophy resulting from a nonsense mutation in th... von Haas, Manuel, Vlcek, Viktor, Balabanov, Pavel, Salmonson, Tomas, Bakchine, Serge, Markey, Greg, Weise, Martina, Schlosser-Weber, Gabriele, Brohmann, Henning, Yerro, Concepcion Prieto, Mendizabal, Macarena Rodriguez, Stoyanova-Beninska, Violeta, Hillege, Hans L

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Reducing valproate use in women with epilepsy von Kälviäinen, Reetta, Straus, Sabine, Dogne, Jean-Michel, Bakchine, Serge, Haas, Manuel

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Stakeholder collaboration for spinal muscular atrophy therapy development von Aartsma-Rus, Annemieke, Balabanov, Pavel, Binetti, Luca, Haas, Manuel, Haberkamp, Marion, Mitchell, Joanna, Rosa, Mário Miguel, Muntoni, Francesco, Finkel, Richard, Mercuri, Eugenio

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Addressing the regulatory and scientific challenges in multiple sclerosis – a statement from the EU regulators von Balabanov, Pavel, Haas, Manuel, Elferink, Andre, Bakchine, Serge, Broich, Karl

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The European Medicines Agency's strategies to meet the challenges of Alzheimer disease von Haas, Manuel, Mantua, Valentina, Haberkamp, Marion, Pani, Luca, Isaac, Maria, Butlen-Ducuing, Florence, Vamvakas, Spiros, Broich, Karl

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Polymer crystallinity and crystallization kinetics via benchtop ^sup 1^H NMR relaxometry: Revisited method, data analysis, and experiments on common polymers von Räntzsch, Volker, Haas, Manuel, Özen, Mürüvvet B, Ratzsch, Karl-Friedrich, Riazi, Kamran, Kauffmann-Weiss, Sandra, Palacios, Jordana K, Müller, Alejandro J, Vittorias, Iakovos, Guthausen, Gisela, Wilhelm, Manfred

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Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer von Jiso, Apisada, Demuth, Philipp, Bachowsky, Madeleine, Haas, Manuel, Seiwert, Nina, Heylmann, Daniel, Rasenberger, Birgit, Christmann, Markus, Dietrich, Lea, Brunner, Thomas, Riyanti, Schaeberle, Till F., Plubrukarn, Anuchit, Fahrer, Joerg

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