Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing von Galanos, Panagiotis, Vougas, Konstantinos, Walter, David, Polyzos, Alexander, Maya-Mendoza, Apolinar, Haagensen, Emma J., Kokkalis, Antonis, Roumelioti, Fani-Marlen, Gagos, Sarantis, Tzetis, Maria, Canovas, Begoña, Igea, Ana, Ahuja, Akshay K., Zellweger, Ralph, Havaki, Sofia, Kanavakis, Emanuel, Kletsas, Dimitris, Roninson, Igor B., Garbis, Spiros D., Lopes, Massimo, Nebreda, Angel, Thanos, Dimitris, Blow, J. Julian, Townsend, Paul, Sørensen, Claus Storgaard, Bartek, Jiri, Gorgoulis, Vassilis G.

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Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells von Moreno, Alberto, Carrington, Jamie T., Albergante, Luca, Mamun, Mohammed Al, Haagensen, Emma J., Komseli, Eirini-Stavroula, Gorgoulis, Vassilis G., Newman, Timothy J., Blow, J. Julian

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Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo antitumour activity in colorectal cancer von Beale, Gary, Haagensen, Emma J, Thomas, Huw D, Wang, Lan-Zhen, Revill, Charlotte H, Payne, Sara L, Golding, Bernard T, Hardcastle, Ian R, Newell, David R, Griffin, Roger J, Cano, Celine

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Co-localisation of intra-nuclear membrane type-1 matrix metalloproteinase and hypoxia inducible factor-2α in osteosarcoma and prostate carcinoma cells von Chan, Corey D, Haagensen, Emma J, Tensaout, Hayeit A, Rennie, Katherine J, Gamie, Zakareya, Barry, James, Birch, Mark A, Gerrand, Craig H, Nisar, Sohail, Robson, Craig N, Lunec, John, Rankin, Kenneth S

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The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines von Gardner, Nicola J., Gillespie, Peter J., Carrington, Jamie T., Shanks, Emma J., McElroy, Stuart P., Haagensen, Emma J., Frearson, Julie A., Woodland, Andrew, Blow, J. Julian

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The enhanced in vivo activity of the combination of a MEK and a PI3K inhibitor correlates with [18F]-FLT PET in human colorectal cancer xenograft tumour-bearing mice von Haagensen, Emma J, Thomas, Huw D, Wilson, Ian, Harnor, Suzannah J, Payne, Sara L, Rennison, Tommy, Smith, Kate M, Maxwell, Ross J, Newell, David R

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The location and development of Replicon Cluster Domains in early replicating DNA von da Costa-Nunes, José A., Gierlinski, Marek, Sasaki, Takayo, Haagensen, Emma J., Gilbert, David M., Blow, J. Julian

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Pre-clinical use of isogenic cell lines and tumours in vitro and in vivo for predictive biomarker discovery; impact of KRAS and PI3KCA mutation status on MEK inhibitor activity is... von Haagensen, Emma J, Thomas, Huw D, Mudd, Clare, Tsonou, Elpida, Wiggins, Ceri M, Maxwell, Ross J, Moore, Jonathan D, Newell, David R

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Enhanced anti-tumour activity of the combination of the novel MEK inhibitor WX-554 and the novel PI3K inhibitor WX-037 von Haagensen, Emma J., Thomas, Huw D., Schmalix, Wolfgang A., Payne, Andrew C., Kevorkian, Lara, Allen, Rodger A., Bevan, Paul, Maxwell, Ross J., Newell, David R.

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The location and development of Replicon Cluster Domains in early replicating DNA von da Costa-Nunes, José A., Gierlinski, Marek, Sasaki, Takayo, Haagensen, Emma J., Gilbert, David M., Blow, J. Julian

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TNF-related apoptosis-inducing ligand (TRAIL) for bone sarcoma treatment: Pre-clinical and clinical data von Gamie, Zakareya, Kapriniotis, Konstantinos, Papanikolaou, Dimitra, Haagensen, Emma, Da Conceicao Ribeiro, Ricardo, Dalgarno, Kenneth, Krippner-Heidenreich, Anja, Gerrand, Craig, Tsiridis, Eleftherios, Rankin, Kenneth Samora

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Co-localisation of intra-nuclear membrane type-1 matrix metalloproteinase and hypoxia inducible factor-2[alpha] in osteosarcoma and prostate carcinoma cells von Chan, Corey D, Haagensen, Emma J, Tensaout, Hayeit A, Rennie, Katherine J, Gamie, Zakareya, Barry, James, Birch, Mark A, Gerrand, Craig H, Nisar, Sohail, Robson, Craig N, Lunec, John, Rankin, Kenneth S

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Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing von Galanos, Panagiotis, Vougas, Konstantinos, Walter, David, Polyzos, Alexander, Maya-Mendoza, Apolinar, Haagensen, Emma J, Kokkalis, Antonis, Roumelioti, Fani-Marlen, Gagos, Sarantis, Tzetis, Maria, Canovas, Begoña, Igea, Ana, Ahuja, Akshay K, Zellweger, Ralph, Havaki, Sofia, Kanavakis, Emanuel, Kletsas, Dimitris, Roninson, Igor B, Garbis, Spiros D, Lopes, Massimo, Nebreda, Angel, Thanos, Dimitris, Blow, J Julian, Townsend, Paul, Sørensen, Claus Storgaard, Bartek, Jiri, Gorgoulis, Vassilis G

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Protracted p53-independent stimulation of p21WAF1/Cip1 fuels genomic instability by deregulating the replication licensing machinery von Galanos, Panagiotis, Vougas, Konstantinos, Walter, David, Polyzos, Alexander, Maya-Mendoza, Apolinar, Haagensen, Emma J., Kokkalis, Antonis, Roumelioti, Fani-Marlen, Gagos, Sarantis, Tzetis, Maria, Canovas, Begoña, Igea, Ana, Kanavakis, Emanuel, Kletsas, Dimitris, Roninson, Igor, Garbis, Spiros D., Nebreda, Angel, Thanos, Dimitris, Townsend, Paul, Blow, J. Julian, Sørensen, Claus Storgaard, Bartek, Jiri, Gorgoulis, Vassilis G.

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Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing von Galanos, Panagiotis, Vougas, Konstantinos, Walter, David, Polyzos, Alexander, Maya-Mendoza, Apolinar, Haagensen, Emma J, Kokkalis, Antonis, Roumelioti, Fani-Marlen, Gagos, Sarantis, Tzetis, Maria, Canovas, Begoña, Igea, Ana, Ahuja, Akshay K, Zellweger, Ralph, Havaki, Sofia, Kanavakis, Emanuel, Kletsas, Dimitris, Roninson, Igor B, Garbis, Spiros D, Lopes, Massimo, Nebreda, Àngel R, Thanos, Dimitris, Blow, J. Julian, Townsend, Paul, Sørensen, Claus Storgaard, Bartek, Jiri, Gorgoulis, Vassilis G

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Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing von Galanos, Panagiotis, Vougas, Konstantinos, Walter, David, Polyzos, Alexander, Maya-Mendoza, Apolinar, Haagensen, Emma J, Kokkalis, Antonis, Roumelioti, Fani-Marlen, Gagos, Sarantis, Tzetis, Maria, Canovas, Begoña, Igea, Ana, Ahuja, Akshay K, Zellweger, Ralph, Havaki, Sofia, Kanavakis, Emanuel, Kletsas, Dimitris, Roninson, Igor B, Garbis, Spiros D, Lopes, Massimo, Nebreda, Àngel R, Thanos, Dimitris, Blow, J. Julian, Townsend, Paul, Sørensen, Claus Storgaard, Bartek, Jiri, Gorgoulis, Vassilis G

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Evaluation of carcinoembryonic antigen as a plasma monitor for human breast carcinoma von Haagensen, Darrow E., Kister, Sven J., Vandevoorde, Jacque P., Gates, Jean B., Smart, Emma K., Hansen, Hans J., Wells, Samuel A.

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