A practical and stereoselective synthesis of (+/−)-trans-4-benzyloctahydropyrrolo[3,4-b][1,4]oxazine von Walker, Daniel P., Strohbach, Joseph W., McGlynn, Molly A., Lu, Hwang-Fun

Volltext

Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design von Walker, Daniel P., Arhancet, Graciela B., Lu, Hwang-Fun, Heasley, Steven E., Metz, Sue, Kablaoui, Natasha M., Franco, Francisco M., Hanau, Cathleen E., Scholten, Jeffrey A., Springer, John R., Fobian, Yvette M., Carter, Jeffrey S., Xing, Li, Yang, Shengtian, Shaffer, Alexander F., Jerome, Gina M., Baratta, Michael T., Moore, William M., Vazquez, Michael L.

Volltext

Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease von Nagarajan, Srinivasan R, De Crescenzo, Gary A, Getman, Daniel P, Lu, Hwang-Fun, Sikorski, James A, Walker, Jeffrey L, McDonald, Joseph J, Houseman, Kathryn A, Kocan, Geralyn P, Kishore, Nandini, Mehta, Pramod P, Funkes-Shippy, Christie L, Blystone, Lisa

Volltext

Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: Protein N-myristoyltransferase: A new approach to antifungal therapy von Sikorski, James A., Devadas, Balekudru, Zupec, Mark E., Freeman, Sandra K., Brown, David L., Lu, Hwang-Fun, Nagarajan, Srinivasan, Mehta, Pramod P., Wade, Arlene C., Kishore, Nandini S., Bryant, Martin L., Getman, Daniel P., McWherter, Charles A., Gordon, Jeffrey I.

Volltext

R-isomers of Arg-Gly-Asp (RGD) mimics as potent αvβ3 inhibitors von NAGARAJAN, Srinivasan R, DEVADAS, Balekudru, LANTZ, Melissa K, JUN ZHU, GREEN, Nawasa F, RUSSELL, Mark A, LANDIS, Bryan H, MILLER, Lawrence M, MEYER, Debra M, DUFFIN, Tiffany D, ENGLEMAN, V. Wayne, FINN, Mary B, MALECHA, James W, FREEMAN, Sandra K, GRIGGS, David W, WILLIAMS, Melanie L, NICKOLS, Maureen A, PEGG, Jodi A, SHANNON, Kristen E, STEININGER, Christina, WESTLIN, Marisa M, NICKOLS, G. Alan, KEENE, Jeffery L, LU, Hwang-Fun, RUMINSKI, Peter G, RICO, Joseph G, ROGERS, Thomas E, MARRUFO, Laura D, COLLINS, Joe T, KLEINE, H. Peter

Volltext

Discovery of + (2 -{4 -[2 -(5,6,7,8 -tetrahydro -1,8 -naphthyridin -2-yl )ethoxy ]phenyl} -cyclopropyl )acetic acid as potent and selective αvβ3 inhibitor : Design, synthesis, and... von NAGARAJAN, Srinivasan R, LU, Hwang-Fun, KEENE, Jeffery L, DUFFIN, Tiffany, ENGLEMAN, V. Wayne, FINN, Mary B, FREEMAN, Sandra K, KLOVER, Jon A, NICKOLS, G. Alan, NICKOLS, Maureen A, SHANNON, Kristen E, STEININGER, Christina A, GASIECKI, Alan F, WESTLIN, William F, WESTLIN, Marisa M, WILLIAMS, Melanie L, KHANNA, Ish K, PARIKH, Mihir D, DESAI, Bipinchandra N, ROGERS, Thomas E, CLARE, Michael, CHEN, Barbara B, RUSSELL, Mark A

Volltext

Conformationally Constrained [p-(ω-Aminoalkyl)phenacetyl]-l-seryl-l-lysyl Dipeptide Amides as Potent Peptidomimetic Inhibitors of Candida albicans and Human Myristoyl-CoA:Protein N... von Nagarajan, Srinivasan R, Devadas, Balekudru, Zupec, Mark E, Freeman, Sandra K, Brown, David L, Lu, Hwang-Fun, Mehta, Pramod P, Kishore, Nandini S, McWherter, Charles A, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A

Volltext

ChemInform Abstract: A Practical and Stereoselective Synthesis of (+/-)-trans-4-Benzyloctahydropyrrolo[3,4-b][1,4]oxazine von Walker, Daniel P., Strohbach, Joseph W., McGlynn, Molly A., Lu, Hwang-Fun

Volltext

Replacements for lysine in l-seryl- l-lysyl dipeptide amide inhibitors of candida albicans myristoyl-CoA:protein N-myristoyltransferase von Brown, David L., Devadas, Balekudru, Lu, Hwang-Fun, Nagarajan, Srinivasan, Zupec, Mark E., Freeman, Sandra K., McWherter, Charles A., Getman, Daniel P., Sikorski, James A.

Volltext

Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective alphavbeta3 inhibitor: design, synthesis, and optimi... von Nagarajan, Srinivasan R, Lu, Hwang-Fun, Gasiecki, Alan F, Khanna, Ish K, Parikh, Mihir D, Desai, Bipinchandra N, Rogers, Thomas E, Clare, Michael, Chen, Barbara B, Russell, Mark A, Keene, Jeffery L, Duffin, Tiffany, Engleman, V Wayne, Finn, Mary B, Freeman, Sandra K, Klover, Jon A, Nickols, G Alan, Nickols, Maureen A, Shannon, Kristen E, Steininger, Christina A, Westlin, William F, Westlin, Marisa M, Williams, Melanie L

Volltext

Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective α vβ 3 inhibitor: Design, synthesis, and optimizatio... von Nagarajan, Srinivasan R., Lu, Hwang-Fun, Gasiecki, Alan F., Khanna, Ish K., Parikh, Mihir D., Desai, Bipinchandra N., Rogers, Thomas E., Clare, Michael, Chen, Barbara B., Russell, Mark A., Keene, Jeffery L., Duffin, Tiffany, Engleman, V. Wayne, Finn, Mary B., Freeman, Sandra K., Klover, Jon A., Nickols, G. Alan, Nickols, Maureen A., Shannon, Kristen E., Steininger, Christina A., Westlin, William F., Westlin, Marisa M., Williams, Melanie L.

Volltext

R-isomers of Arg-Gly-Asp (RGD) mimics as potent alphavbeta3 inhibitors von Nagarajan, Srinivasan R, Devadas, Balekudru, Malecha, James W, Lu, Hwang-Fun, Ruminski, Peter G, Rico, Joseph G, Rogers, Thomas E, Marrufo, Laura D, Collins, Joe T, Kleine, H Peter, Lantz, Melissa K, Zhu, Jun, Green, Nawasa F, Russell, Mark A, Landis, Bryan H, Miller, Lawrence M, Meyer, Debra M, Duffin, Tiffany D, Engleman, V Wayne, Finn, Mary B, Freeman, Sandra K, Griggs, David W, Williams, Melanie L, Nickols, Maureen A, Pegg, Jodi A, Shannon, Kristen E, Steininger, Christina, Westlin, Marisa M, Nickols, G Alan, Keene, Jeffery L

Volltext

R-Isomers of Arg-Gly-Asp (RGD) mimics as potent α vβ 3 inhibitors von Nagarajan, Srinivasan R., Devadas, Balekudru, Malecha, James W., Lu, Hwang-Fun, Ruminski, Peter G., Rico, Joseph G., Rogers, Thomas E., Marrufo, Laura D., Collins, Joe T., Kleine, H. Peter, Lantz, Melissa K., Zhu, Jun, Green, Nawasa F., Russell, Mark A., Landis, Bryan H., Miller, Lawrence M., Meyer, Debra M., Duffin, Tiffany D., Engleman, V. Wayne, Finn, Mary B., Freeman, Sandra K., Griggs, David W., Williams, Melanie L., Nickols, Maureen A., Pegg, Jodi A., Shannon, Kristen E., Steininger, Christina, Westlin, Marisa M., Nickols, G. Alan, Keene, Jeffery L.

Volltext

Design and Synthesis of Novel Imidazole-Substituted Dipeptide Amides as Potent and Selective Inhibitors of Candida albicans MyristoylCoA:Protein N-Myristoyltransferase and Identifi... von Devadas, Balekudru, Freeman, Sandra K, Zupec, Mark E, Lu, Hwang-Fun, Nagarajan, Srinivasan R, Kishore, Nandini S, Lodge, Jennifer K, Kuneman, David W, McWherter, Charles A, Vinjamoori, Dutt V, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A

Volltext

Structure-activity studies of fluoroalkyl-substituted gamma-butyrolactone and gamma-thiobutyrolactone modulators of GABA(A) receptor function von Canney, D J, Lu, H F, McKeon, A C, Yoon, K W, Xu, K, Holland, K D, Rothman, S M, Ferrendelli, J A, Covey, D F

Volltext

Structure-activity studies of fluoroaljyl-substituted γ-butyrolactone and γ-thiobutyrolactone modulators of GABAA receptor function von Canney, Daniel J., Lu, Hwang-Fun, McKeon, Ann C., Yoon, Kong-Woo, Xu, Kun, Holland, Katherine D., Rothman, Steven M., Ferrendelli, James A., Covey, Douglas F.

Volltext

Structure-activity studies of fluoroaljyl-substituted γ-butyrolactone and γ-thiobutyrolactone modulators of GABA A receptor function von Canney, Daniel J., Lu, Hwang-Fun, McKeon, Ann C., Yoon, Kong-Woo, Xu, Kun, Holland, Katherine D., Rothman, Steven M., Ferrendelli, James A., Covey, Douglas F.

Volltext

Facile Synthesis of α, β, and/or γ-Alkyl-Substituted γ-Butyrolactones Using Readily Prepared Olefinic Esters von Canney, Daniel J., Levine, Jeffrey A., Lu, Hwang-Fun, Covey, Douglas F.

Volltext

Cycloalkyl alkanoic acids as integrin receptor antagonists von Clare, Michael, Khanna, Ish Kumar, Gasiecki, Alan, Rogers, Thomas, Chen, Barbara, Lu, Hwang-Fun

Volltext bestellen

Pyrazole substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors von Sikorski, James, Talley, John, Graneto, Matthew, Norman, Bryan, Devadas, Balekudru, Lu, Hwang-Fun

Volltext bestellen