A practical and stereoselective synthesis of (+/−)-trans-4-benzyloctahydropyrrolo[3,4-b][1,4]oxazine von Walker, Daniel P., Strohbach, Joseph W., McGlynn, Molly A., Lu, Hwang-Fun

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Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design von Walker, Daniel P., Arhancet, Graciela B., Lu, Hwang-Fun, Heasley, Steven E., Metz, Sue, Kablaoui, Natasha M., Franco, Francisco M., Hanau, Cathleen E., Scholten, Jeffrey A., Springer, John R., Fobian, Yvette M., Carter, Jeffrey S., Xing, Li, Yang, Shengtian, Shaffer, Alexander F., Jerome, Gina M., Baratta, Michael T., Moore, William M., Vazquez, Michael L.

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ChemInform Abstract: A Practical and Stereoselective Synthesis of (+/-)-trans-4-Benzyloctahydropyrrolo[3,4-b][1,4]oxazine von Walker, Daniel P., Strohbach, Joseph W., McGlynn, Molly A., Lu, Hwang-Fun

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Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease von Nagarajan, Srinivasan R, De Crescenzo, Gary A, Getman, Daniel P, Lu, Hwang-Fun, Sikorski, James A, Walker, Jeffrey L, McDonald, Joseph J, Houseman, Kathryn A, Kocan, Geralyn P, Kishore, Nandini, Mehta, Pramod P, Funkes-Shippy, Christie L, Blystone, Lisa

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Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: Protein N-myristoyltransferase: A new approach to antifungal therapy von Sikorski, James A., Devadas, Balekudru, Zupec, Mark E., Freeman, Sandra K., Brown, David L., Lu, Hwang-Fun, Nagarajan, Srinivasan, Mehta, Pramod P., Wade, Arlene C., Kishore, Nandini S., Bryant, Martin L., Getman, Daniel P., McWherter, Charles A., Gordon, Jeffrey I.

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R-isomers of Arg-Gly-Asp (RGD) mimics as potent αvβ3 inhibitors von NAGARAJAN, Srinivasan R, DEVADAS, Balekudru, LANTZ, Melissa K, JUN ZHU, GREEN, Nawasa F, RUSSELL, Mark A, LANDIS, Bryan H, MILLER, Lawrence M, MEYER, Debra M, DUFFIN, Tiffany D, ENGLEMAN, V. Wayne, FINN, Mary B, MALECHA, James W, FREEMAN, Sandra K, GRIGGS, David W, WILLIAMS, Melanie L, NICKOLS, Maureen A, PEGG, Jodi A, SHANNON, Kristen E, STEININGER, Christina, WESTLIN, Marisa M, NICKOLS, G. Alan, KEENE, Jeffery L, LU, Hwang-Fun, RUMINSKI, Peter G, RICO, Joseph G, ROGERS, Thomas E, MARRUFO, Laura D, COLLINS, Joe T, KLEINE, H. Peter

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Discovery of + (2 -{4 -[2 -(5,6,7,8 -tetrahydro -1,8 -naphthyridin -2-yl )ethoxy ]phenyl} -cyclopropyl )acetic acid as potent and selective αvβ3 inhibitor : Design, synthesis, and... von NAGARAJAN, Srinivasan R, LU, Hwang-Fun, KEENE, Jeffery L, DUFFIN, Tiffany, ENGLEMAN, V. Wayne, FINN, Mary B, FREEMAN, Sandra K, KLOVER, Jon A, NICKOLS, G. Alan, NICKOLS, Maureen A, SHANNON, Kristen E, STEININGER, Christina A, GASIECKI, Alan F, WESTLIN, William F, WESTLIN, Marisa M, WILLIAMS, Melanie L, KHANNA, Ish K, PARIKH, Mihir D, DESAI, Bipinchandra N, ROGERS, Thomas E, CLARE, Michael, CHEN, Barbara B, RUSSELL, Mark A

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Replacements for lysine in l-seryl- l-lysyl dipeptide amide inhibitors of candida albicans myristoyl-CoA:protein N-myristoyltransferase von Brown, David L., Devadas, Balekudru, Lu, Hwang-Fun, Nagarajan, Srinivasan, Zupec, Mark E., Freeman, Sandra K., McWherter, Charles A., Getman, Daniel P., Sikorski, James A.

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Conformationally Constrained [p-(ω-Aminoalkyl)phenacetyl]-l-seryl-l-lysyl Dipeptide Amides as Potent Peptidomimetic Inhibitors of Candida albicans and Human Myristoyl-CoA:Protein N... von Nagarajan, Srinivasan R, Devadas, Balekudru, Zupec, Mark E, Freeman, Sandra K, Brown, David L, Lu, Hwang-Fun, Mehta, Pramod P, Kishore, Nandini S, McWherter, Charles A, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A

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Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective alphavbeta3 inhibitor: design, synthesis, and optimi... von Nagarajan, Srinivasan R, Lu, Hwang-Fun, Gasiecki, Alan F, Khanna, Ish K, Parikh, Mihir D, Desai, Bipinchandra N, Rogers, Thomas E, Clare, Michael, Chen, Barbara B, Russell, Mark A, Keene, Jeffery L, Duffin, Tiffany, Engleman, V Wayne, Finn, Mary B, Freeman, Sandra K, Klover, Jon A, Nickols, G Alan, Nickols, Maureen A, Shannon, Kristen E, Steininger, Christina A, Westlin, William F, Westlin, Marisa M, Williams, Melanie L

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Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective α vβ 3 inhibitor: Design, synthesis, and optimizatio... von Nagarajan, Srinivasan R., Lu, Hwang-Fun, Gasiecki, Alan F., Khanna, Ish K., Parikh, Mihir D., Desai, Bipinchandra N., Rogers, Thomas E., Clare, Michael, Chen, Barbara B., Russell, Mark A., Keene, Jeffery L., Duffin, Tiffany, Engleman, V. Wayne, Finn, Mary B., Freeman, Sandra K., Klover, Jon A., Nickols, G. Alan, Nickols, Maureen A., Shannon, Kristen E., Steininger, Christina A., Westlin, William F., Westlin, Marisa M., Williams, Melanie L.

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Structure-activity studies of fluoroaljyl-substituted γ-butyrolactone and γ-thiobutyrolactone modulators of GABA A receptor function von Canney, Daniel J., Lu, Hwang-Fun, McKeon, Ann C., Yoon, Kong-Woo, Xu, Kun, Holland, Katherine D., Rothman, Steven M., Ferrendelli, James A., Covey, Douglas F.

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Structure-activity studies of fluoroaljyl-substituted γ-butyrolactone and γ-thiobutyrolactone modulators of GABAA receptor function von Canney, Daniel J., Lu, Hwang-Fun, McKeon, Ann C., Yoon, Kong-Woo, Xu, Kun, Holland, Katherine D., Rothman, Steven M., Ferrendelli, James A., Covey, Douglas F.

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R-isomers of Arg-Gly-Asp (RGD) mimics as potent alphavbeta3 inhibitors von Nagarajan, Srinivasan R, Devadas, Balekudru, Malecha, James W, Lu, Hwang-Fun, Ruminski, Peter G, Rico, Joseph G, Rogers, Thomas E, Marrufo, Laura D, Collins, Joe T, Kleine, H Peter, Lantz, Melissa K, Zhu, Jun, Green, Nawasa F, Russell, Mark A, Landis, Bryan H, Miller, Lawrence M, Meyer, Debra M, Duffin, Tiffany D, Engleman, V Wayne, Finn, Mary B, Freeman, Sandra K, Griggs, David W, Williams, Melanie L, Nickols, Maureen A, Pegg, Jodi A, Shannon, Kristen E, Steininger, Christina, Westlin, Marisa M, Nickols, G Alan, Keene, Jeffery L

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R-Isomers of Arg-Gly-Asp (RGD) mimics as potent α vβ 3 inhibitors von Nagarajan, Srinivasan R., Devadas, Balekudru, Malecha, James W., Lu, Hwang-Fun, Ruminski, Peter G., Rico, Joseph G., Rogers, Thomas E., Marrufo, Laura D., Collins, Joe T., Kleine, H. Peter, Lantz, Melissa K., Zhu, Jun, Green, Nawasa F., Russell, Mark A., Landis, Bryan H., Miller, Lawrence M., Meyer, Debra M., Duffin, Tiffany D., Engleman, V. Wayne, Finn, Mary B., Freeman, Sandra K., Griggs, David W., Williams, Melanie L., Nickols, Maureen A., Pegg, Jodi A., Shannon, Kristen E., Steininger, Christina, Westlin, Marisa M., Nickols, G. Alan, Keene, Jeffery L.

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Design and Synthesis of Novel Imidazole-Substituted Dipeptide Amides as Potent and Selective Inhibitors of Candida albicans MyristoylCoA:Protein N-Myristoyltransferase and Identifi... von Devadas, Balekudru, Freeman, Sandra K, Zupec, Mark E, Lu, Hwang-Fun, Nagarajan, Srinivasan R, Kishore, Nandini S, Lodge, Jennifer K, Kuneman, David W, McWherter, Charles A, Vinjamoori, Dutt V, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A

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Structure-activity studies of fluoroalkyl-substituted gamma-butyrolactone and gamma-thiobutyrolactone modulators of GABA(A) receptor function von Canney, D J, Lu, H F, McKeon, A C, Yoon, K W, Xu, K, Holland, K D, Rothman, S M, Ferrendelli, J A, Covey, D F

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Facile Synthesis of α, β, and/or γ-Alkyl-Substituted γ-Butyrolactones Using Readily Prepared Olefinic Esters von Canney, Daniel J., Levine, Jeffrey A., Lu, Hwang-Fun, Covey, Douglas F.

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Pyrazolo[4,3-D]pyrimidines von Bell, Andrew Simon, Brown, David Graham, Fox, David Nathan Abraham, Marsh, Ian Roger, Morrell, Andrew Ian, Owen, Dafydd Rhys, Palmer, Michael John, Winslow, Carol Ann, Lu, Hwang Fun, Rogers, Thomas Edward

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Cycloalkyl alkanoic acids as integrin receptor antagonists von Clare, Michael, Khanna, Ish Kumar, Gasiecki, Alan, Rogers, Thomas, Chen, Barbara, Lu, Hwang-Fun

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