Inhibition of Human Telomerase by a G-Quadruplex-Interactive Compound von Sun, Daekyu, Thompson, Brian, Cathers, Brian E, Salazar, Miguel, Kerwin, Sean M, Trent, John O, Jenkins, Terence C, Neidle, Stephen, Hurley, Laurence H

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Selective Interactions of Cationic Porphyrins with G-Quadruplex Structures von Han, Haiyong, Langley, David R, Rangan, Anupama, Hurley, Laurence H

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Quadruplex-Interactive Agents as Telomerase Inhibitors:  Synthesis of Porphyrins and Structure−Activity Relationship for the Inhibition of Telomerase von Shi, Dong-Fang, Wheelhouse, Richard T, Sun, Daekyu, Hurley, Laurence H

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DNA and its associated processes as targets for cancer therapy von Hurley, Laurence H

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Ecteinascidin 743:  A Minor Groove Alkylator That Bends DNA toward the Major Groove von Zewail-Foote, Maha, Hurley, Laurence H

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Cationic Porphyrins as Telomerase Inhibitors:  the Interaction of Tetra-(N-methyl-4-pyridyl)porphine with Quadruplex DNA von Wheelhouse, Richard T, Sun, Daekyu, Han, Haiyong, Han, Frank Xiaoguang, Hurley, Laurence H

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A DNA polymerase stop assay for G-quadruplex-interactive compounds von Han, Haiyong, Hurley, Laurence H., Salazar, Miguel

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Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor gene von Guo, Kexiao, Gokhale, Vijay, Hurley, Laurence H., Sun, Daekyu

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Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells von IZBICKA, E, WHEELHOUSE, R. T, RAYMOND, E, DAVIDSON, K. K, LAWRENCE, R. A, SUN, D, WINDLE, B. E, HURLEY, L. H, VON HOFF, D. D

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Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4 von Qin, Yong, Rezler, Evonne M, Gokhale, Vijay, Sun, Daekyu, Hurley, Laurence H

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Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription von Siddiqui-Jain, Adam, Grand, Cory L., Bearss, David J., Hurley, Laurence H.

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Differential Rates of Reversibility of Ecteinascidin 743−DNA Covalent Adducts from Different Sequences Lead to Migration to Favored Bonding Sites von Zewail-Foote, Maha, Hurley, Laurence H

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Cationic Porphyrins Promote the Formation of i-Motif DNA and Bind Peripherally by a Nonintercalative Mechanism von Fedoroff, Oleg Yu, Rangan, Anupama, Chemeris, Violetta V, Hurley, Laurence H

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G-quadruplex DNA: a potential target for anti-cancer drug design von Han, Haiyong, Hurley, Laurence H

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Inhibition of Unwinding of G-Quadruplex Structures by Sgs1 Helicase in the Presence of N,N‘-Bis[2-(1-piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic Diimide, a G-Quadruplex-Inte... von Han, Haiyong, Bennett, Richard J, Hurley, Laurence H

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Interactions of TMPyP4 and TMPyP2 with Quadruplex DNA. Structural Basis for the Differential Effects on Telomerase Inhibition von Han, Frank Xiaoguang, Wheelhouse, Richard T, Hurley, Laurence H

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Design and Synthesis of a Novel DNA−DNA Interstrand Adenine−Guanine Cross-Linking Agent von Zhou, Qun, Duan, Wenhu, Simmons, Denise, Shayo, Yuda, Raymond, Mary Ann, Dorr, Robert T, Hurley, Laurence H

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Mechanism for the Catalytic Activation of Ecteinascidin 743 and Its Subsequent Alkylation of Guanine N2 von Moore, Bob M, Seaman, Frederick C, Wheelhouse, Richard T, Hurley, Laurence H

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Induction of Duplex to G-quadruplex Transition in the c-myc Promoter Region by a Small Molecule von Rangan, Anupama, Fedoroff, Oleg Yu, Hurley, Laurence H.

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DNA and associated targets for drug design von Hurley, Laurence H

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