Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA von Mackiewicz, Mark, Huppi, Konrad, Pitt, Jason J., Dorsey, Tiffany H., Ambs, Stefan, Caplen, Natasha J.

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The Identification of MicroRNAs in a Genomically Unstable Region of Human Chromosome 8q24 von Huppi, Konrad, Volfovsky, Natalia, Runfola, Timothy, Jones, Tamara L, Mackiewicz, Mark, Martin, Scott E, Mushinski, J Frederic, Stephens, Robert, Caplen, Natasha J

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Pvt1-encoded microRNAs in oncogenesis von Beck-Engeser, Gabriele B, Lum, Amy M, Huppi, Konrad, Caplen, Natasha J, Wang, Bruce B, Wabl, Matthias

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Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma von Grohar, Patrick J., Kim, Suntae, Rangel Rivera, Guillermo O., Sen, Nirmalya, Haddock, Sara, Harlow, Matt L., Maloney, Nichole K., Zhu, Jack, O’Neill, Maura, Jones, Tamara L., Huppi, Konrad, Grandin, Magdalena, Gehlhaus, Kristen, Klumpp-Thomas, Carleen A., Buehler, Eugen, Helman, Lee J., Martin, Scott E., Caplen, Natasha J.

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Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2 , and PTK6 as sensitizing targets of rapamycin activity von Ou, Oliver, Huppi, Konrad, Chakka, Sirisha, Gehlhaus, Kristen, Dubois, Wendy, Patel, Jyoti, Chen, Jinqiu, Mackiewicz, Mark, Jones, Tamara L, Pitt, Jason J, Martin, Scott E, Goldsmith, Paul, Simmons, John K, Mock, Beverly A, Caplen, Natasha J

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The 8q24 Gene Desert: An Oasis of Non-Coding Transcriptional Activity von Huppi, Konrad, Pitt, Jason J., Wahlberg, Brady M., Caplen, Natasha J.

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p53-dependent Induction of PVT1 and miR-1204 von Barsotti, Anthony M., Beckerman, Rachel, Laptenko, Oleg, Huppi, Konrad, Caplen, Natasha J., Prives, Carol

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Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal... von Hummon, Amanda B, Pitt, Jason J, Camps, Jordi, Emons, Georg, Skube, Susan B, Huppi, Konrad, Jones, Tamara L, Beissbarth, Tim, Kramer, Frank, Grade, Marian, Difilippantonio, Michael J, Ried, Thomas, Caplen, Natasha J

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Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma von Abnet, Christian C, Huppi, Konrad, Carrera, Ana, Armistead, David, McKenney, Keith, Hu, Nan, Tang, Ze-Zong, Taylor, Philip R, Dawsey, Sanford M

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Abstract 2635: Role of LRRC15, a candidate immunotherapy target, in cell adhesion, migration and spheroid formation in osteosarcoma cells von Mukherjee, Sanjit, Huppi, Konrad, Walker, Robert L., Zhu, Jack, Pineda, Marbin, Purcell, James W., Helman, Lee J., Meltzer, Paul S.

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Abstract 3119: LRRC15, a candidate immunotherapy target, regulates cell-cell interaction, migration and spheroid formation in osteosarcoma cells von Mukherjee, Sanjit, Huppi, Konrad, Walker, Robert L., Zhu, Jack, Pineda, Marbin, Yang, Fan, Purcell, James, Helman, Lee J., Meltzer, Paul S.

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Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice von Raveche, Elizabeth S., Salerno, Erica, Scaglione, Brian J., Manohar, Vijaya, Abbasi, Fatima, Lin, Yi-Chu, Fredrickson, Torgny, Landgraf, Pablo, Ramachandra, Sumant, Huppi, Konrad, Toro, Jorge R., Zenger, Vincent E., Metcalf, Robert A., Marti, Gerald E.

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Defining and Assaying RNAi in Mammalian Cells von Huppi, Konrad, Martin, Scott E., Caplen, Natasha J.

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Abstract 3204: The identification of AURKB, BUB1B and CDK18 as putative molecular targets for breast cancer using kinome focused RNAi screens von Ou, Lihui, Gehlhaus, Kristen, Jones, Tamara, Huppi, Konrad, Caplen, Natasha

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Abstract IA04: Targeting the expression of EWS-FLI1 von Sen, Nirmalya, Ludwig, Katelyn, Rangel-Rivera, Guillermo O., Kim, Suntae, Huppi, Konrad, Jenkins, Lisa, Dwyer, Jennifer E., Hoover, Shelley, Helman, Lee, Simpson, Mark, Mendoza, Arnulfo, Hummon, Amanda B., Caplen, Natasha J.

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Abstract 267: Large-scale RNAi screening of human kinome identifies putative breast cancer related molecular targets von Ou, Oliver, Huppi, Konrad, Gehlhaus, Kristen, Jones, Tamara, Caplen, Natasha

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Insertional hypermutation in mineral oil‐induced plasmacytomas von Knittel, Gero, Metzner, Mirjam, Beck‐Engeser, Gabriele, Kan, Ada, Ahrends, Tomasz, Eilat, Dan, Huppi, Konrad, Wabl, Matthias

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Abstract 2008: Ewing sarcoma cells harboring a translocation that retains EWSR1 exon 8 require HNRNPH1 to express the in-frame oncogenic fusion transcript EWS-FLI1 von Kim, Suntae, Olivero, Christiane, Rangel Rivera, Guillermo O., Sen, Nirmalya, Haddock, Sara, Huppi, Konrad, Helman, Lee J., Grohar, Patrick J., Caplen, Natasha J.

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Abstract 2041: Large-scale RNAi screening identifies PCTK3/CDK18 as a putative cancer-related molecular target von Ou, Lihui, Huppi, Konrad, Gehlhaus, Kristen, Jones, Tamara, Caplen, Natasha

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Abstract 479: Inhibition of the splicing of the EWS-FLI1 fusion transcript reverses EWS-FLI1 driven oncogenic expression in Ewing sarcoma von Grohar, Patrick J., Kim, Suntae, Haddock, Sara, Rangel Rivera, Guillermo, Harlow, Matt, Maloney, Nichole K., Huppi, Konrad, Gehlhaus, Kristen, Grandin, Magdalena, Klumpp-Thomas, Carleen, Buehler, Eugen, Helman, Lee J., Martin, Scott E., Caplen, Natasha J.

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