Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels von Roider, Tobias, Seufert, Julian, Uvarovskii, Alexey, Frauhammer, Felix, Bordas, Marie, Abedpour, Nima, Stolarczyk, Marta, Mallm, Jan-Philipp, Herbst, Sophie A., Bruch, Peter-Martin, Balke-Want, Hyatt, Hundemer, Michael, Rippe, Karsten, Goeppert, Benjamin, Seiffert, Martina, Brors, Benedikt, Mechtersheimer, Gunhild, Zenz, Thorsten, Peifer, Martin, Chapuy, Björn, Schlesner, Matthias, Müller-Tidow, Carsten, Fröhling, Stefan, Huber, Wolfgang, Anders, Simon, Dietrich, Sascha

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Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single‐cell transcriptomics von Tirier, Stephan M., Mallm, Jan-Philipp, Steiger, Simon, Poos, Alexandra M., Awwad, Mohamed H. S., Giesen, Nicola, Casiraghi, Nicola, Susak, Hana, Bauer, Katharina, Baumann, Anja, John, Lukas, Seckinger, Anja, Hose, Dirk, Müller-Tidow, Carsten, Goldschmidt, Hartmut, Stegle, Oliver, Hundemer, Michael, Weinhold, Niels, Raab, Marc S., Rippe, Karsten

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Late-onset NPM1 mutation in a MYC-amplified relapsed / refractory acute myeloid leukemia patient treated with gemtuzumab ozogamicin and glasdegib von Jaramillo, Sonia, Scherer, Michael, Szu-Tu, Chelsea, Beneyto-Calabuig, Sergi, Müller-Tidow, Carsten, Schlenk, Richard F, Hundemer, Michael, Velten, Lars, Pabst, Caroline

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CD38 as Immunotherapeutic Target in Light Chain Amyloidosis and Multiple Myeloma-Association With Molecular Entities, Risk, Survival, and Mechanisms of Upfront Resistance von Seckinger, Anja, Hillengass, Jens, Emde, Martina, Beck, Susanne, Kimmich, Christoph, Dittrich, Tobias, Hundemer, Michael, Jauch, Anna, Hegenbart, Ute, Raab, Marc-Steffen, Ho, Anthony D, Schönland, Stefan, Hose, Dirk

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Impact of novel agent therapies on immune cell subsets and infectious complications in patients with relapsed/refractory multiple myeloma von John, Lukas, Miah, Kaya, Benner, Axel, Mai, Elias K, Kriegsmann, Katharina, Hundemer, Michael, Kaudewitz, Dorothee, Müller-Tidow, Carsten, Jordan, Karin, Goldschmidt, Hartmut, Raab, Marc S, Giesen, Nicola

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Rationale and design of the German-speaking myeloma multicenter group (GMMG) trial HD6: a randomized phase III trial on the effect of elotuzumab in VRD induction/consolidation and... von Salwender, Hans, Bertsch, Uta, Weisel, Katja, Duerig, Jan, Kunz, Christina, Benner, Axel, Blau, Igor W, Raab, Marc Steffen, Hillengass, Jens, Hose, Dirk, Huhn, Stefanie, Hundemer, Michael, Andrulis, Mindaugas, Jauch, Anna, Seidel-Glaetzer, Andrea, Lindemann, Hans-Walter, Hensel, Manfred, Fronhoffs, Stefan, Martens, Uwe, Hansen, Timon, Wattad, Mohammed, Graeven, Ullrich, Munder, Markus, Fenk, Roland, Haenel, Mathias, Scheid, Christof, Goldschmidt, Hartmut

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Early Development of Ubiquitous Acanthocytosis and Extravascular Hemolysis in Lung Cancer Patients Receiving Alectinib von Kunz, Julia, Wiedemann, Christiane, Grosch, Heidrun, Kriegsmann, Katharina, Gryzik, Stefanie, Felden, Julia, Hundemer, Michael, Seker-Cin, Huriye, Stenzinger, Miriam, Leo, Albrecht, Stenzinger, Albrecht, Thomas, Michael, Christopoulos, Petros

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CCR5 status and metastatic progression in colorectal cancer von Suarez-Carmona, Meggy, Chaorentong, Pornpimol, Kather, Jakob Nikolas, Rothenheber, Rebecca, Ahmed, Azaz, Berthel, Anna, Heinzelmann, Anita, Moraleda, Rodrigo, Valous, Nektarios A., Kosaloglu, Zeynep, Eurich, Rosa, Wolf, Jana, Grauling-Halama, Silke, Hundemer, Michael, Lasitschka, Felix, Klupp, Fee, Kahlert, Christoph, Ulrich, Alexis, Schneider, Martin, Falk, Christine, Jäger, Dirk, Zoernig, Inka, Halama, Niels

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The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor von Sprynski, Anne Catherine, Hose, Dirk, Caillot, Laurent, Réme, Thierry, Shaughnessy, John D., Barlogie, Bart, Seckinger, Anja, Moreaux, Jérôme, Hundemer, Michael, Jourdan, Michel, Meißner, Tobias, Jauch, Anna, Mahtouk, Karène, Kassambara, Alboukadel, Bertsch, Uta, Rossi, Jean François, Goldschmidt, Hartmut, Klein, Bernard

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Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia von Dietrich, Sascha, Hüllein, Jennifer, Hundemer, Michael, Lehners, Nicola, Jethwa, Alexander, Capper, David, Acker, Till, Garvalov, Boyan K, Andrulis, Mindaugas, Blume, Carolin, Schulte, Christoph, Mandel, Thomas, Meissner, Julia, Fröhling, Stefan, von Kalle, Christof, Glimm, Hanno, Ho, Anthony D, Zenz, Thorsten

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Induction of angiogenesis by normal and malignant plasma cells von Hose, Dirk, Moreaux, Jérôme, Meissner, Tobias, Seckinger, Anja, Goldschmidt, Hartmut, Benner, Axel, Mahtouk, Karène, Hillengass, Jens, Rème, Thierry, De Vos, John, Hundemer, Michael, Condomines, Maud, Bertsch, Uta, Rossi, Jean-François, Jauch, Anna, Klein, Bernard, Möhler, Thomas

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Q-HAM: a multicenter upfront randomized phase II trial of quizartinib and high-dose Ara-C plus mitoxantrone in relapsed/refractory AML with FLT3-ITD von Jaramillo, Sonia, Le Cornet, Lucian, Kratzmann, Markus, Krisam, Johannes, Görner, Martin, Hänel, Mathias, Röllig, Christoph, Wass, Maxi, Scholl, Sebastian, Ringhoffer, Mark, Reichart, Alexander, Steffen, Björn, Kayser, Sabine, Mikesch, Jan-Henrik, Schaefer-Eckart, Kerstin, Schubert, Jörg, Geer, Thomas, Martin, Sonja, Kieser, Meinhard, Sauer, Tim, Kriegsmann, Katharina, Hundemer, Michael, Serve, Hubert, Bornhäuser, Martin, Müller-Tidow, Carsten, Schlenk, Richard F

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Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma von Mahtouk, Karène, Hose, Dirk, Raynaud, Pierre, Hundemer, Michael, Jourdan, Michel, Jourdan, Eric, Pantesco, Veronique, Baudard, Marion, De Vos, John, Larroque, Marion, Moehler, Thomas, Rossi, Jean-Francois, Rème, Thierry, Goldschmidt, Hartmut, Klein, Bernard

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IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells von Kehl, Niklas, Kilian, Michael, Michel, Julius, Wagner, Tim R, Uhrig, Sebastian, Brobeil, Alexander, Sester, Lilli-Sophie, Blobner, Sven, Steiger, Simon, Hundemer, Michael, Weinhold, Niels, Rippe, Karsten, Fröhling, Stefan, Eichmüller, Stefan B, Bunse, Lukas, Müller-Tidow, Carsten, Goldschmidt, Hartmut, Platten, Michael, Raab, Marc-Steffen, Friedrich, Mirco J

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The prognostic and predictive value of IKZF1 and IKZF3 expression in T-cells in patients with multiple myeloma von Awwad, Mohamed H. S., Kriegsmann, Katharina, Plaumann, Julian, Benn, Michael, Hillengass, Jens, Raab, Marc S., Bertsch, Uta, Munder, Markus, Weisel, Katja, Salwender, Hans Jürgen, Hänel, Mathias, Fenk, Roland, Dürig, Jan, Müller-Tidow, Carsten, Goldschmidt, Hartmut, Hundemer, Michael

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Cytotoxicity of tumor antigen specific human T cells is unimpaired by arginine depletion von Munder, Markus, Engelhardt, Melanie, Knies, Diana, Medenhoff, Sergej, Wabnitz, Guido, Luckner-Minden, Claudia, Feldmeyer, Nadja, Voss, Ralf-Holger, Kropf, Pascale, Müller, Ingrid, Conradi, Roland, Samstag, Yvonne, Theobald, Matthias, Ho, Anthony D, Goldschmidt, Hartmut, Hundemer, Michael

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P408: COMBINATORIAL BCL‐2 FAMILY EXPRESSION IN ACUTE MYELOID LEUKEMIA STEM CELLS PREDICTS CLINICAL RESPONSE TO AZACITIDINE/VENETOCLAX von Renders, Simon, Waclawiczek, Alexander, Leppä, Aino‐Maija, Stumpf, Karolin, Betz, Barbara, Reyneri, Cecilia, Donato, Elisa, Janssen, Maike, Unglaub, Julia, Shahswar, Rabia, Raffel, Simon, Hundemer, Michael, Heuser, Michael, Müller‐Tidow, Carsten, Sauer, Tim, Trumpp, Andreas

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Cancer/Testis Genes in Multiple Myeloma: Expression Patterns and Prognosis Value Determined by Microarray Analysis von Condomines, Maud, Hose, Dirk, Raynaud, Pierre, Hundemer, Michael, De Vos, John, Baudard, Marion, Moehler, Thomas, Pantesco, Veronique, Moos, Marion, Schved, Jean-Francois, Rossi, Jean-Francois, Reme, Thierry, Goldschmidt, Hartmut, Klein, Bernard

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Potential therapeutic targets in plasma cell disorders: A flow cytometry study von Lisenko, Katharina, Schönland, Stefan, Hegenbart, Ute, Wallenwein, Katrin, Braun, Ute, Mai, Elias K., Hillengass, Jens, Goldschmidt, Hartmut, Jauch, Anna, Ho, Anthony D., Raab, Marc, Hundemer, Michael

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S189: PROTEOGENOMIC LANDSCAPE OF MULTIPLE MYELOMA von Ramberger, Evelyn, Dolnik, Anna, Ng, Yuen Lam Dora, Ziehm, Matthias, Popp, Oliver, Sträng, Eric, Kull, Miriam, Sapozhnikova, Valeriia, Grünschläger, Florian, Benary, Manuela, Müller, Sina, Gao, Xiang, Murgai, Arunima, Haji, Mohamed, Schmidt, Annika, Lutz, Raphael, Nogai, Axel, Braune, Jan, Laue, Dominik, Langer, Christian, Khandanpour, Cyrus, Bassermann, Florain, Döhner, Hartmut, Engelhardt, Monika, Straka, Christian, Hundemer, Michael, Haas, Simon, Beule, Dieter, Keller, Ulrich, Einsele, Hermann, Bullinger, Lars, Knop, Stefan, Mertins, Philipp, Krönke, Jan

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