Generating Genetically Modified Mice: A Decision Guide von Huijbers, Ivo J.

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A role for fibrillar collagen deposition and the collagen internalization receptor endo180 in glioma invasion von Huijbers, Ivo J, Iravani, Marjan, Popov, Sergey, Robertson, David, Al-Sarraj, Safa, Jones, Chris, Isacke, Clare M

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Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients von Semenova, Ekaterina A., Kwon, Min-chul, Monkhorst, Kim, Song, Ji-Ying, Bhaskaran, Rajith, Krijgsman, Oscar, Kuilman, Thomas, Peters, Dennis, Buikhuisen, Wieneke A., Smit, Egbert F., Pritchard, Colin, Cozijnsen, Miranda, van der Vliet, Jan, Zevenhoven, John, Lambooij, Jan-Paul, Proost, Natalie, van Montfort, Erwin, Velds, Arno, Huijbers, Ivo J., Berns, Anton

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TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth/differentiation and breast cancer development von Cornelissen, Lisette M., Drenth, Anne Paulien, van der Burg, Eline, de Bruijn, Roebi, Pritchard, Colin E. J., Huijbers, Ivo J., Zwart, Wilbert, Jonkers, Jos

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Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer von Henneman, Linda, van Miltenburg, Martine H., Michalak, Ewa M., Braumuller, Tanya M., Jaspers, Janneke E., Drenth, Anne Paulien, de Korte-Grimmerink, Renske, Gogola, Ewa, Szuhai, Karoly, Schlicker, Andreas, Ali, Rahmen Bin, Pritchard, Colin, Huijbers, Ivo J., Berns, Anton, Rottenberg, Sven, Jonkers, Jos

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Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland von Annunziato, Stefano, Kas, Sjors M, Nethe, Micha, Yücel, Hatice, Del Bravo, Jessica, Pritchard, Colin, Bin Ali, Rahmen, van Gerwen, Bas, Siteur, Bjørn, Drenth, Anne Paulien, Schut, Eva, van de Ven, Marieke, Boelens, Mirjam C, Klarenbeek, Sjoerd, Huijbers, Ivo J, van Miltenburg, Martine H, Jonkers, Jos

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Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism von Loregger, Anke, Raaben, Matthijs, Nieuwenhuis, Joppe, Tan, Josephine M. E., Jae, Lucas T., van den Hengel, Lisa G., Hendrix, Sebastian, van den Berg, Marlene, Scheij, Saskia, Song, Ji-Ying, Huijbers, Ivo J., Kroese, Lona J., Ottenhoff, Roelof, van Weeghel, Michel, van de Sluis, Bart, Brummelkamp, Thijn, Zelcer, Noam

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Balancing selection of a frame-shift mutation in the MRC2 gene accounts for the outbreak of the Crooked Tail Syndrome in Belgian Blue Cattle von Fasquelle, Corinne, Sartelet, Arnaud, Li, Wanbo, Dive, Marc, Tamma, Nico, Michaux, Charles, Druet, Tom, Huijbers, Ivo J, Isacke, Clare M, Coppieters, Wouter, Georges, Michel, Charlier, Carole

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Pericytes promote selective vessel regression to regulate vascular patterning von Simonavicius, Nicole, Ashenden, Matthew, van Weverwijk, Antoinette, Lax, Siân, Huso, David L., Buckley, Christopher D., Huijbers, Ivo J., Yarwood, Helen, Isacke, Clare M.

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Deubiquitinase catalytic activity of MYSM1 is essential in vivo for hematopoiesis and immune cell development von Liang, Yue, Bhatt, Garvit, Tung, Lin Tze, Wang, HanChen, Kim, Joo Eun, Mousa, Marwah, Plackoska, Viktoria, Illes, Katalin, Georges, Anna A., Gros, Philippe, Henneman, Linda, Huijbers, Ivo J., Nagar, Bhushan, Nijnik, Anastasia

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Towards an understanding of C9orf82 protein/CAAP1 function von Aslam, Muhammad Assad, Alemdehy, Mir Farshid, Pritchard, Colin E J, Song, Ji-Ying, Muhaimin, Fitriari Izzatunnisa, Wijdeven, Ruud H, Huijbers, Ivo J, Neefjes, Jacques, Jacobs, Heinz

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In situ CRISPR‐Cas9 base editing for the development of genetically engineered mouse models of breast cancer von Annunziato, Stefano, Lutz, Catrin, Henneman, Linda, Bhin, Jinhyuk, Wong, Kim, Siteur, Bjørn, van Gerwen, Bas, de Korte‐Grimmerink, Renske, Zafra, Maria Paz, Schatoff, Emma M, Drenth, Anne Paulien, van der Burg, Eline, Eijkman, Timo, Mukherjee, Siddhartha, Boroviak, Katharina, Wessels, Lodewyk FA, van de Ven, Marieke, Huijbers, Ivo J, Adams, David J, Dow, Lukas E, Jonkers, Jos

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HideRNAs protect against CRISPR-Cas9 re-cutting after successful single base-pair gene editing von Harmsen, Tim J. W., Pritchard, Colin E. J., Riepsaame, Joey, van de Vrugt, Henri J., Huijbers, Ivo J., te Riele, Hein

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Colorectal carcinoma progression is not influenced by the pseudokinase PEAK1 von Zuidema, Alba, Atherton, Paul, van der Poel, Sabine, Kreft, Maaike, Song, Ji-Ying, Bierbooms, Martine, Verhoeven, Sophie, Papagianni, Chrysoula, Kroese, Lona, Ali, Rahmen Bin, Huijbers, Ivo, Carvalho, Beatriz, Sonnenberg, Arnoud

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Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL von Antoszewski, Mateusz, Fournier, Nadine, Ruiz Buendía, Gustavo A., Lourenco, Joao, Liu, Yuanlong, Sugrue, Tara, Dubey, Christelle, Nkosi, Marianne, Pritchard, Colin E.J., Huijbers, Ivo J., Segat, Gabriela C., Alonso-Moreno, Sandra, Serracanta, Elisabeth, Belver, Laura, Ferrando, Adolfo A., Ciriello, Giovanni, Weng, Andrew P., Koch, Ute, Radtke, Freddy

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Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division von Maia, Ana Rita R., Linder, Simon, Song, Ji-Ying, Vaarting, Chantal, Boon, Ute, Pritchard, Colin E. J., Velds, Arno, Huijbers, Ivo J., van Tellingen, Olaf, Jonkers, Jos, Medema, René H.

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Direct Generation of Conditional Alleles Using CRISPR/Cas9 in Mouse Zygotes von Pritchard, Colin E. J., Kroese, Lona J., Huijbers, Ivo J.

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Mammalian life depends on two distinct pathways of DNA damage tolerance von Buoninfante, Olimpia Alessandra, Pilzecker, Bas, Spanjaard, Aldo, de Groot, Daniël, Prekovic, Stefan, Song, Ji-Ying, Lieftink, Cor, Ayidah, Matilda, Pritchard, Colin E J, Vivié, Judith, Mcgrath, Kathleen E, Huijbers, Ivo J, Philipsen, Sjaak, von Lindern, Marieke, Zwart, Wilbert, Beijersbergen, Roderick L, Palis, James, van den Berk, Paul C M, Jacobs, Heinz

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Rapid target gene validation in complex cancer mouse models using re‐derived embryonic stem cells von Huijbers, Ivo J, Bin Ali, Rahmen, Pritchard, Colin, Cozijnsen, Miranda, Kwon, Min‐Chul, Proost, Natalie, Song, Ji‐Ying, de Vries, Hilda, Badhai, Jitendra, Sutherland, Kate, Krimpenfort, Paul, Michalak, Ewa M, Jonkers, Jos, Berns, Anton

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USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells von van den Berk, Paul, Lancini, Cesare, Company, Carlos, Serresi, Michela, Sanchez-Bailon, Maria Pilar, Hulsman, Danielle, Pritchard, Colin, Song, Ji-Ying, Schmitt, Matthias Jürgen, Tanger, Ellen, Popp, Oliver, Mertins, Philipp, Huijbers, Ivo J., Jacobs, Heinz, van Lohuizen, Maarten, Gargiulo, Gaetano, Citterio, Elisabetta

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