Cellular and in Vivo Activity of JNJ-28871063, A Nonquinazoline Pan-ErbB Kinase Inhibitor That Crosses the Blood-Brain Barrier and Displays Efficacy against Intracranial Tumors von Emanuel, Stuart L, Hughes, Terry V, Adams, Mary, Rugg, Catherine A, Fuentes-Pesquera, Angel, Connolly, Peter J, Pandey, Niranjan, Moreno-Mazza, Sandra, Butler, Jeannene, Borowski, Virna, Middleton, Steven A, Gruninger, Robert H, Story, Jennifer R, Napier, Cheryl, Hollister, Beth, Greenberger, Lee M

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Synthesis and evaluation of 2,7-diamino-thiazolo[4,5- d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors von Lin, Ronghui, Johnson, Sigmond G., Connolly, Peter J., Wetter, Steven K., Binnun, Eva, Hughes, Terry V., Murray, William V., Pandey, Niranjan B., Moreno-Mazza, Sandra J., Adams, Mary, Fuentes-Pesquera, Angel R., Middleton, Steven A.

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Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors von Haffner, Curt D, Charnley, Adam K, Aquino, Christopher J, Casillas, Linda, Convery, Máire A, Cox, Julie A, Elban, Mark A, Goodwin, Nicole C, Gough, Peter J, Haile, Pamela A, Hughes, Terry V, Knapp-Reed, Beth, Kreatsoulas, Constantine, Lakdawala, Ami S, Li, Huijie, Lian, Yiqian, Lipshutz, David, Mehlmann, John F, Ouellette, Michael, Romano, Joseph, Shewchuk, Lisa, Shu, Arthur, Votta, Bartholomew J, Zhou, Huiqiang, Bertin, John, Marquis, Robert W

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A Convenient New Synthesis of 1-Cyanobenzotriazole and Its Use as a C-Cyanating Reagent von Hughes, Terry V, Hammond, Stephen D, Cava, Michael P

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Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel von Haile, Pamela A, Casillas, Linda N, Bury, Michael J, Mehlmann, John F, Singhaus, Robert, Charnley, Adam K, Hughes, Terry V, DeMartino, Michael P, Wang, Gren Z, Romano, Joseph J, Dong, Xiaoyang, Plotnikov, Nikolay V, Lakdawala, Ami S, Convery, Maire A, Votta, Bartholomew J, Lipshutz, David B, Desai, Biva M, Swift, Barbara, Capriotti, Carol A, Berger, Scott B, Mahajan, Mukesh K, Reilly, Michael A, Rivera, Elizabeth J, Sun, Helen H, Nagilla, Rakesh, LePage, Carol, Ouellette, Michael T, Totoritis, Rachel D, Donovan, Brian T, Brown, Barry S, Chaudhary, Khuram W, Gough, Peter J, Bertin, John, Marquis, Robert W

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Unimolecular Electrical Rectification in Hexadecylquinolinium Tricyanoquinodimethanide von Metzger, Robert M, Chen, Bo, Höpfner, Ulf, Lakshmikantham, M. V, Vuillaume, Dominique, Kawai, Tsuyoshi, Wu, Xiangli, Tachibana, Hiroaki, Hughes, Terry V, Sakurai, Hiromi, Baldwin, Jeffrey W, Hosch, Christina, Cava, Michael P, Brehmer, Ludwig, Ashwell, Geoffrey J

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Correction to Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel von Haile, Pamela A., Casillas, Linda N., Bury, Michael J., Mehlmann, John F., Singhaus, Robert, Charnley, Adam K., Hughes, Terry V., DeMartino, Michael P., Wang, Gren Z., Romano, Joseph J., Dong, Xiaoyang, Plotnikov, Nikolay V., Lakdawala, Ami S., Duraiswami, Chaya, Convery, Maire A., Votta, Bartholomew J., Lipshutz, David B., Desai, Biva M., Swift, Barbara, Capriotti, Carol A., Berger, Scott B., Mahajan, Mukesh K., Reilly, Michael A., Rivera, Elizabeth J., Sun, Helen H., Nagilla, Rakesh, LePage, Carol, Ouellette, Michael T., Totoritis, Rachel D., Donovan, Brian T., Brown, Barry S., Chaudhary, Khuram W., Gough, Peter J., Bertin, John, Marquis, Robert W.

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Spectroscopic Studies of Hexadecylquinolinium Tricyanoquinodimethanide von Baldwin, Jeffrey W, Chen, Bo, Street, Shane C, Konovalov, Valery V, Sakurai, Hiromi, Hughes, Terry V, Simpson, Camino S, Lakshmikantham, M. V, Cava, Michael P, Kispert, Lowell D, Metzger, Robert M

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Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases von Xu, Guozhang, Searle, Lily Lee, Hughes, Terry V., Beck, Amanda K., Connolly, Peter J., Abad, Marta C., Neeper, Michael P., Struble, Geoffrey T., Springer, Barry A., Emanuel, Stuart L., Gruninger, Robert H., Pandey, Niranjan, Adams, Mary, Moreno-Mazza, Sandra, Fuentes-Pesquera, Angel R., Middleton, Steven A., Greenberger, Lee M.

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A novel 5-[1,3,4-oxadiazol-2-yl]-N-aryl-4,6-pyrimidine diamine having dual EGFR/HER2 kinase activity: Design, synthesis, and biological activity von Hughes, Terry V., Xu, Guozhang, Wetter, Steven K., Connolly, Peter J., Emanuel, Stuart L., Karnachi, Prabha, Pollack, Scott R., Pandey, Niranjan, Adams, Mary, Moreno-Mazza, Sandra, Middleton, Steven A., Greenberger, Lee M.

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Electrophilic Cyanations Using 1-Cyanobenzotriazole: sp(2) and sp Carbanions von Hughes, Terry V., Cava, Michael P.

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7-[1 H-Indol-2-yl]-2,3-dihydro-isoindol-1-ones as dual Aurora-A/VEGF-R2 kinase inhibitors: Design, synthesis, and biological activity von Hughes, Terry V., Emanuel, Stuart L., O’Grady, Harold R., Connolly, Peter J., Rugg, Catherine, Fuentes-Pesquera, Angel R., Karnachi, Prabha, Alexander, Richard, Middleton, Steven A.

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4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: Synthesis and biological evaluation von Hughes, Terry V., Emanuel, Stuart L., Beck, Amanda K., Wetter, Steven K., Connolly, Peter J., Karnachi, Prabha, Reuman, Michael, Seraj, Jabed, Fuentes-Pesquera, Angel R., Gruninger, Robert H., Middleton, Steven A., Lin, Ronghui, Davis, Jeremy M., Moffat, David F.C.

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Establishing the Parabolic Relationship between Reactivity and Activity for Derivatives and Analogues of the Duocarmycin and CC-1065 Alkylation Subunits von Parrish, Jay P, Hughes, Terry V, Hwang, Inkyu, Boger, Dale L

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Synthesis, Chemical Properties, and Biological Evaluation of CC-1065 and Duocarmycin Analogues Incorporating the 5-Methoxycarbonyl-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-on... von Boger, Dale L, Hughes, Terry V, Hedrick, Michael P

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Electrophilic Cyanations Using 1-Cyanobenzotriazole:  sp2 and sp Carbanions von Hughes, Terry V, Cava, Michael P

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Synthesis and evaluation of N-aryl and N-alkenyl CBI derivatives von Parrish, Jay P., Trzupek, John D., Hughes, Terry V., Hwang, Inkyu, Boger, Dale L.

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Electrophilic Cyanations Using 1-Cyanobenzotriazole:  sp2 and sp Carbanions von Hughes, Terry V, Michael P. Cava

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Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel (vol 9, pg 1039, 2018) von Haile, Pamela A., Casillas, Linda N., Bury, Michael J., Mehlmann, John F., Singhaus, Robert, Charnley, Adam K., Hughes, Terry V., DeMartino, Michael P., Wang, Gren Z., Romano, Joseph J., Dong, Xiaoyang, Plotnikov, Nikolay V., Lakdawala, Ami S., Duraiswami, Chaya, Convery, Maire A., Votta, Bartholomew J., Lipshutz, David B., Desai, Biva M., Swift, Barbara, Capriotti, Carol A., Berger, Scott B., Mahajan, Mukesh K., Reilly, Michael A., Rivera, Elizabeth J., Sun, Helen H., Nagilla, Rakesh, LePage, Carol, Ouellette, Michael T., Totoritis, Rachel D., Donovan, Brian T., Brown, Barry S., Chaudhary, Khuram W., Gough, Peter J., Bertin, John, Marquis, Robert W.

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Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors von Ha, #64256, ner, Curt D., Charnley, Adam K., Aquino, Christopher J., Casillas, Linda, Convery, Ma, #769, ire, A., Cox, Julie A., Elban, Mark A., Goodwin, Nicole C., Gough, Peter J., Haile, Pamela A., Hughes, Terry V., Knapp-Reed, Beth, Kreatsoulas, Constantine, Lakdawala, Ami S., Li, Huijie, Lian, Yiqian, Lipshutz, David, Mehlmann, John F., Ouellette, Michael, Romano, Joseph, Shewchuk, Lisa, Shu, Arthur, Votta, Bartholomew J., Zhou, Huiqiang, Bertin, John, Marquis, Robert W.

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