Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome von Witztum, Joseph L, Gaudet, Daniel, Freedman, Steven D, Alexander, Veronica J, Digenio, Andres, Williams, Karren R, Yang, Qingqing, Hughes, Steven G, Geary, Richard S, Arca, Marcello, Stroes, Erik S.G, Bergeron, Jean, Soran, Handrean, Civeira, Fernando, Hemphill, Linda, Tsimikas, Sotirios, Blom, Dirk J, O’Dea, Louis, Bruckert, Eric

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N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levels von Alexander, Veronica J, Xia, Shuting, Hurh, Eunju, Hughes, Steven G, O’Dea, Louis, Geary, Richard S, Witztum, Joseph L, Tsimikas, Sotirios

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Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials von Viney, Nicholas J, BSc, van Capelleveen, Julian C, MD, Geary, Richard S, PhD, Xia, Shuting, MS, Tami, Joseph A, PharmD, Yu, Rosie Z, PhD, Marcovina, Santica M, Prof, Hughes, Steven G, MD, Graham, Mark J, MS, Crooke, Rosanne M, PhD, Crooke, Stanley T, MD, Witztum, Joseph L, Prof, Stroes, Erik S, Prof, Tsimikas, Sotirios, Prof

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Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study von Tsimikas, Sotirios, Prof, Viney, Nicholas J, BSc, Hughes, Steven G, MBBS, Singleton, Walter, MD, Graham, Mark J, MS, Baker, Brenda F, PhD, Burkey, Jennifer L, PhD, Yang, Qingqing, MS, Marcovina, Santica M, Prof, Geary, Richard S, PhD, Crooke, Rosanne M, PhD, Witztum, Joseph L, Prof

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A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs von Yan, He, Wen, Yunjie, Tian, Zimu, Hart, Nathan, Han, Song, Hughes, Steven J., Zeng, Yong

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Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides von Graham, Mark J, Lee, Richard G, Brandt, Teresa A, Tai, Li-Jung, Fu, Wuxia, Peralta, Raechel, Yu, Rosie, Hurh, Eunju, Paz, Erika, McEvoy, Bradley W, Baker, Brenda F, Pham, Nguyen C, Digenio, Andres, Hughes, Steven G, Geary, Richard S, Witztum, Joseph L, Crooke, Rosanne M, Tsimikas, Sotirios

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Targeting APOC3 in the Familial Chylomicronemia Syndrome von Gaudet, Daniel, Brisson, Diane, Tremblay, Karine, Alexander, Veronica J, Singleton, Walter, Hughes, Steven G, Geary, Richard S, Baker, Brenda F, Graham, Mark J, Crooke, Rosanne M, Witztum, Joseph L

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From tumor microenvironment communicants to biomarker discovery: Selectively packaged extracellular vesicular cargoes in pancreatic cancer von Han, Song, Underwood, Patrick, Hughes, Steven J.

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Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis von Benson, Merrill D, Waddington-Cruz, Márcia, Berk, John L, Polydefkis, Michael, Dyck, Peter J, Wang, Annabel K, Planté-Bordeneuve, Violaine, Barroso, Fabio A, Merlini, Giampaolo, Obici, Laura, Scheinberg, Morton, Brannagan, Thomas H, Litchy, William J, Whelan, Carol, Drachman, Brian M, Adams, David, Heitner, Stephen B, Conceição, Isabel, Schmidt, Hartmut H, Vita, Giuseppe, Campistol, Josep M, Gamez, Josep, Gorevic, Peter D, Gane, Edward, Shah, Amil M, Solomon, Scott D, Monia, Brett P, Hughes, Steven G, Kwoh, T. Jesse, McEvoy, Bradley W, Jung, Shiangtung W, Baker, Brenda F, Ackermann, Elizabeth J, Gertz, Morie A, Coelho, Teresa

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Robot-assisted minimally invasive distal pancreatectomy is superior to the laparoscopic technique von Daouadi, Mustapha, Zureikat, Amer H, Zenati, Mazen S, Choudry, Haroon, Tsung, Alan, Bartlett, David L, Hughes, Steven J, Lee, Ken K, Moser, A James, Zeh, Herbert J

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Cation Exchange Reactions in Ionic Nanocrystals von Son, Dong Hee, Hughes, Steven M., Yin, Yadong, Alivisatos, A. Paul

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Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia von Gaudet, Daniel, Alexander, Veronica J, Baker, Brenda F, Brisson, Diane, Tremblay, Karine, Singleton, Walter, Geary, Richard S, Hughes, Steven G, Viney, Nicholas J, Graham, Mark J, Crooke, Rosanne M, Witztum, Joseph L, Brunzell, John D, Kastelein, John J.P

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Antisense-Mediated Lowering of Plasma Apolipoprotein C-III by Volanesorsen Improves Dyslipidemia and Insulin Sensitivity in Type 2 Diabetes von Digenio, Andres, Dunbar, Richard L, Alexander, Veronica J, Hompesch, Marcus, Morrow, Linda, Lee, Richard G, Graham, Mark J, Hughes, Steven G, Yu, Rosie, Singleton, Walter, Baker, Brenda F, Bhanot, Sanjay, Crooke, Rosanne M

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Rectal cancer patients younger than 50 years lack a survival benefit from NCCN guideline–directed treatment for stage II and III disease von Kolarich, Andrew, George, Thomas J., Hughes, Steven J., Delitto, Daniel, Allegra, Carmen J., Hall, William A., Chang, George J., Tan, Sanda A., Shaw, Christiana M., Iqbal, Atif

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The use of pancreatic enzyme replacement therapy in patients with a diagnosis of chronic pancreatitis and pancreatic cancer in the US is infrequent and inconsistent von Forsmark, Chris E., Tang, Gong, Xu, Hongzhi, Tuft, Marie, Hughes, Steven J., Yadav, Dhiraj

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Intestinal microbiota enhances pancreatic carcinogenesis in preclinical models von Thomas, Ryan M, Gharaibeh, Raad Z, Gauthier, Josee, Beveridge, Mark, Pope, Jillian L, Guijarro, Maria V, Yu, Qin, He, Zhen, Ohland, Christina, Newsome, Rachel, Trevino, Jose, Hughes, Steven J, Reinhard, Mary, Winglee, Kathryn, Fodor, Anthony A, Zajac-Kaye, Maria, Jobin, Christian

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An Integrated Safety Analysis of Infants and Children with Symptomatic Spinal Muscular Atrophy (SMA) Treated with Nusinersen in Seven Clinical Trials von Darras, Basil T., Farrar, Michelle A., Mercuri, Eugenio, Finkel, Richard S., Foster, Richard, Hughes, Steven G., Bhan, Ishir, Farwell, Wildon, Gheuens, Sarah

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Patient and Procedural Determinants of Postoperative Pain Trajectories von Vasilopoulos, Terrie, Wardhan, Richa, Rashidi, Parisa, Fillingim, Roger B., Wallace, Margaret R., Crispen, Paul L., Parvataneni, Hari K., Prieto, Hernan A., Machuca, Tiago N., Hughes, Steven J., Murad, Gregory J. A., Tighe, Patrick J.

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Circadian Photoentrainment in Mice and Humans von Foster, Russell G, Hughes, Steven, Peirson, Stuart N

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Diversification of Academic Surgery, Its Leadership, and the Importance of Intersectionality von Riner, Andrea N, Herremans, Kelly M, Neal, Daniel W, Johnson-Mann, Crystal, Hughes, Steven J, McGuire, Kandace P, Upchurch, Gilbert R, Trevino, Jose G

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