Chromatin interaction maps identify Wnt responsive cis-regulatory elements coordinating Paupar-Pax6 expression in neuronal cells von Pavlaki, Ioanna, Shapiro, Michael, Pisignano, Giuseppina, Jones, Stephanie M E, Telenius, Jelena, Muñoz-Descalzo, Silvia, Williams, Robert J, Hughes, Jim R, Vance, Keith W

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Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment von Hughes, Jim R, Roberts, Nigel, McGowan, Simon, Hay, Deborah, Giannoulatou, Eleni, Lynch, Magnus, De Gobbi, Marco, Taylor, Stephen, Gibbons, Richard, Higgs, Douglas R

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Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers von Bejjani, Fabienne, Tolza, Claire, Boulanger, Mathias, Downes, Damien, Romero, Raphaël, Maqbool, Muhammad Ahmad, Zine El Aabidine, Amal, Andrau, Jean-Christophe, Lebre, Sophie, Brehelin, Laurent, Parrinello, Hughes, Rohmer, Marine, Kaoma, Tony, Vallar, Laurent, Hughes, Jim R, Zibara, Kazem, Lecellier, Charles-Henri, Piechaczyk, Marc, Jariel-Encontre, Isabelle

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Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus von Downes, Damien J., Cross, Amy R., Hua, Peng, Roberts, Nigel, Schwessinger, Ron, Cutler, Antony J., Munis, Altar M., Brown, Jill, Mielczarek, Olga, de Andrea, Carlos E., Melero, Ignacio, Gill, Deborah R., Hyde, Stephen C., Knight, Julian C., Todd, John A., Sansom, Stephen N., Issa, Fadi, Davies, James O. J., Hughes, Jim R.

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Unlinking an lncRNA from Its Associated cis Element von Paralkar, Vikram R., Taborda, Cristian C., Huang, Peng, Yao, Yu, Kossenkov, Andrew V., Prasad, Rishi, Luan, Jing, Davies, James O.J., Hughes, Jim R., Hardison, Ross C., Blobel, Gerd A., Weiss, Mitchell J.

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Single-cell technologies meet Hi-C von Hughes, Jim R., Davies, James O. J.

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Multiplexed analysis of chromosome conformation at vastly improved sensitivity von Davies, James O J, Telenius, Jelena M, McGowan, Simon J, Roberts, Nigel A, Taylor, Stephen, Higgs, Douglas R, Hughes, Jim R

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Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo von Hanssen, Lars L. P., Kassouf, Mira T., Oudelaar, A. Marieke, Biggs, Daniel, Preece, Chris, Downes, Damien J., Gosden, Matthew, Sharpe, Jacqueline A., Sloane-Stanley, Jacqueline A., Hughes, Jim R., Davies, Benjamin, Higgs, Douglas R.

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ATRX plays a key role in maintaining silencing at interstitial heterochromatic loci and imprinted genes von Voon, Hsiao P.J, Hughes, Jim R., Rode, Christina, De La Rosa-Velázquez, Inti A., Jenuwein, Thomas, Feil, Robert, Higgs, Douglas R., Gibbons, Richard J.

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DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation von Godfrey, Laura, Crump, Nicholas T., Thorne, Ross, Lau, I-Jun, Repapi, Emmanouela, Dimou, Dimitra, Smith, Alastair L., Harman, Joe R., Telenius, Jelena M., Oudelaar, A. Marieke, Downes, Damien J., Vyas, Paresh, Hughes, Jim R., Milne, Thomas A.

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Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder von Long, Hannah K., Osterwalder, Marco, Welsh, Ian C., Hansen, Karissa, Davies, James O.J., Liu, Yiran E., Koska, Mervenaz, Adams, Alexander T., Aho, Robert, Arora, Neha, Ikeda, Kazuya, Williams, Ruth M., Sauka-Spengler, Tatjana, Porteus, Matthew H., Mohun, Tim, Dickel, Diane E., Swigut, Tomek, Hughes, Jim R., Higgs, Douglas R., Visel, Axel, Selleri, Licia, Wysocka, Joanna

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Intragenic Enhancers Act as Alternative Promoters von Kowalczyk, Monika S., Hughes, Jim R., Garrick, David, Lynch, Magnus D., Sharpe, Jacqueline A., Sloane-Stanley, Jacqueline A., McGowan, Simon J., De Gobbi, Marco, Hosseini, Mona, Vernimmen, Douglas, Brown, Jill M., Gray, Nicola E., Collavin, Licio, Gibbons, Richard J., Flint, Jonathan, Taylor, Stephen, Buckle, Veronica J., Milne, Thomas A., Wood, William G., Higgs, Douglas R.

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Dynamics of the 4D genome during in vivo lineage specification and differentiation von Oudelaar, A. Marieke, Beagrie, Robert A., Gosden, Matthew, de Ornellas, Sara, Georgiades, Emily, Kerry, Jon, Hidalgo, Daniel, Carrelha, Joana, Shivalingam, Arun, El-Sagheer, Afaf H., Telenius, Jelena M., Brown, Tom, Buckle, Veronica J., Socolovsky, Merav, Higgs, Douglas R., Hughes, Jim R.

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A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition von Traxler, Elizabeth A, Yao, Yu, Wang, Yong-Dong, Woodard, Kaitly J, Kurita, Ryo, Nakamura, Yukio, Hughes, Jim R, Hardison, Ross C, Blobel, Gerd A, Li, Chunliang, Weiss, Mitchell J

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Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element von Huang, Peng, Keller, Cheryl A, Giardine, Belinda, Grevet, Jeremy D, Davies, James O J, Hughes, Jim R, Kurita, Ryo, Nakamura, Yukio, Hardison, Ross C, Blobel, Gerd A

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A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus von Oudelaar, A. Marieke, Harrold, Caroline L., Hanssen, Lars L. P., Telenius, Jelena M., Higgs, Douglas R., Hughes, Jim R.

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DeepC: predicting 3D genome folding using megabase-scale transfer learning von Schwessinger, Ron, Gosden, Matthew, Downes, Damien, Brown, Richard C., Oudelaar, A. Marieke, Telenius, Jelena, Teh, Yee Whye, Lunter, Gerton, Hughes, Jim R.

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Defining genome architecture at base-pair resolution von Hua, Peng, Badat, Mohsin, Hanssen, Lars L. P., Hentges, Lance D., Crump, Nicholas, Downes, Damien J., Jeziorska, Danuta M., Oudelaar, A. Marieke, Schwessinger, Ron, Taylor, Stephen, Milne, Thomas A., Hughes, Jim R., Higgs, Doug R., Davies, James O. J.

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How best to identify chromosomal interactions: a comparison of approaches von Davies, James O J, Oudelaar, A Marieke, Higgs, Douglas R, Hughes, Jim R

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Your best day: An interactive app to translate how time reallocations within a 24-hour day are associated with health measures von Dumuid, Dorothea, Olds, Timothy, Wake, Melissa, Lund Rasmussen, Charlotte, Pedisic, Zeljko, Hughes, Jim H, Foster, David JR, Walmsley, Rosemary, Atkin, Andrew J, Straker, Leon, Fraysse, Francois, Smith, Ross T, Neumann, Frank, Kenett, Ron S, Jarle Mork, Paul, Bennett, Derrick, Doherty, Aiden, Stanford, Ty

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