Editorial on “Advances in downstream processing of biologics – Spectroscopy: An emerging process analytical technology” by Matthias Rüdt, Till Briskot and Jürgen Hubbuch von Poole, Colin F.

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Rapid Analysis for Multicomponent High-Throughput Crystallization Screening: Combination of UV–Vis Spectroscopy and Chemometrics von Wegner, Christina H., Zimmermann, Ines, Hubbuch, Jürgen

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Effective removal of host cell-derived nucleic acids bound to hepatitis B core antigen virus-like particles by heparin chromatography von Valentic, Angela, Hubbuch, Jürgen

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Simulating and Optimizing Preparative Protein Chromatography with ChromX von Hahn, Tobias, Huuk, Thiemo, Heuveline, Vincent, Hubbuch, Jürgen

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A critical review of recent trends, and a future perspective of optical spectroscopy as PAT in biopharmaceutical downstream processing von Rolinger, Laura, Rüdt, Matthias, Hubbuch, Jürgen

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Calibration-free PAT: Locating selective crystallization or precipitation sweet spot in screenings with multi-way PARAFAC models von Wegner, Christina Henriette, Hubbuch, Jürgen

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Modeling of hydrophobic interaction chromatography for the separation of antibody-drug conjugates and its application towards quality by design von Andris, Sebastian, Hubbuch, Jürgen

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Investigation of Lysozyme Diffusion in Agarose Hydrogels Employing a Microfluidics-Based UV Imaging Approach von Wenger, Lukas, Hubbuch, Jürgen

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Size-selective downstream processing of virus particles and non-enveloped virus-like particles von Hillebrandt, Nils, Hubbuch, Jürgen

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Straightforward method for calibration of mechanistic cation exchange chromatography models for industrial applications von Saleh, David, Wang, Gang, Müller, Benedict, Rischawy, Federico, Kluters, Simon, Studts, Joey, Hubbuch, Jürgen

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Impact of Polymer Bioconjugation on Protein Stability and Activity Investigated with Discrete Conjugates: Alternatives to PEGylation von Morgenstern, Josefine, Gil Alvaradejo, Gabriela, Bluthardt, Nicolai, Beloqui, Ana, Delaittre, Guillaume, Hubbuch, Jürgen

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Absolute Quantification of Hepatitis B Core Antigen (HBcAg) Virus-like Particles and Bound Nucleic Acids von Valentic, Angela, Böhner, Nicola, Hubbuch, Jürgen

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Process monitoring framework for cross‐flow diafiltration‐based virus‐like particle disassembly: Tracing product properties and filtration performance von Hillebrandt, Nils, Vormittag, Philipp, Dietrich, Annabelle, Hubbuch, Jürgen

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Protein adsorption on ion exchange adsorbers: A comparison of a stoichiometric and non-stoichiometric modeling approach von Briskot, Till, Hahn, Tobias, Huuk, Thiemo, Hubbuch, Jürgen

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RP-CAD for Lipid Quantification: Systematic Method Development and Intensified LNP Process Characterization von Beckert, Nicole, Dietrich, Annabelle, Hubbuch, Jürgen

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Dual-Stage Cross-Flow Filtration: Integrated Capture and Purification of Virus-Like Particles von Dietrich, Annabelle, Heim, Luca, Hubbuch, Jürgen

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Raman spectroscopy as a process analytical technology to investigate biopharmaceutical freeze concentration processes von Weber, Dennis, Hubbuch, Jürgen

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Kinetic reaction modeling for antibody-drug conjugate process development von Andris, Sebastian, Seidel, Jonathan, Hubbuch, Jürgen

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Investigation of the reversibility of freeze/thaw stress-induced protein instability using heat cycling as a function of different cryoprotectants von Wöll, Anna K., Hubbuch, Jürgen

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Multi-attribute PAT for UF/DF of Proteins—Monitoring Concentration, particle sizes, and Buffer Exchange von Rolinger, Laura, Rüdt, Matthias, Diehm, Juliane, Chow-Hubbertz, Jessica, Heitmann, Martin, Schleper, Stefan, Hubbuch, Jürgen

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