Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA von Liu, M.C., Klein, E.A., Swanton, C., Seiden, M.V., Klein, Eric A., Yeatman, Timothy J., Cohn, Allen L., Lapham, Rosanna, Parker, Alexander S., McIntyre, Kristi, Sekeres, Mikkael A., Siegel, Robert, Wang, Xuezhong, Cosgrove, David P., Trent, Jonathan, Thiel, David D., Garbo, Lawrence E., Giguere, Jeffrey K., Michels, Ross M., Harris, Ronald P., Richey, Stephen L., McCarthy, Timothy A., Couch, Fergus J., Wilks, Sharon T., Krie, Amy K., Balaraman, Rama, Rieger-Christ, Kimberly, Sullivan, Travis, Greenwald, Daniel R., Oh, William, Tsao, Che-Kai, Kennecke, Hagen F., Manhas, Atisha P., Ulrich, Brian K., Kovoor, Philip A., Stokoe, Christopher, Courtright, Jay G., Larson, Timothy G., Seiden, Michael V., Cummings, Steven R., Absalan, Farnaz, Alexander, Gregory, Allen, Brian, Aravanis, Alexander M., Beausang, John F., Berman, Jennifer, Bredno, Joerg, Calef, Robert, Cann, Gordon, Carter, Jeremy, Chen, Xiaoji, Chien, Tom C., Davydov, Konstantin, Demas, Vasiliki, Fields, Alexander P., Freese, Peter, Gnerre, Sante, Gross, Samuel, Hall, Megan P., Hartman, Anne-Renee, Hou, Chenlu, Hubbell, Earl, Jiang, Roger, Kim, TaeHyung, Klausner, Richard D., Kurtzman, Kathryn N., Lee, Mark, Lin, Wendy, Lipson, Jafi, Maddala, Tara, Maher, M. Cyrus, Melton, Collin, Mich, Andrea, Newman, Joshua, Nicula, Virgil, Nikolic, Ongjen, Patel, Shilpen, Rava, Richard, Schellenberger, Jan, Scott, Eric, Sehnert, Amy J., Shaknovich, Rita, Shanmugam, Avinash, Shashidhar, K.C., Shenoy, Archana, Shojaee, Seyedmehdi, Tang, Susan, Valouev, Anton, Venn, Oliver, Williams, Richard T., Wu, Tony, Yakym, Christopher, Yang, Xiao, Yecies, Jessica, Yip, Alexander S., Yue, Jeanne, Zhang, Lily, Zhang, Lori (Quan), Curtis, Christina, Berry, Donald A.

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High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants von Razavi, Pedram, Li, Bob T., Brown, David N., Jung, Byoungsok, Hubbell, Earl, Shen, Ronglai, Abida, Wassim, Juluru, Krishna, De Bruijn, Ino, Hou, Chenlu, Venn, Oliver, Lim, Raymond, Anand, Aseem, Maddala, Tara, Gnerre, Sante, Vijaya Satya, Ravi, Liu, Qinwen, Shen, Ling, Eattock, Nicholas, Yue, Jeanne, Blocker, Alexander W., Lee, Mark, Sehnert, Amy, Xu, Hui, Hall, Megan P., Santiago-Zayas, Angie, Novotny, William F., Isbell, James M., Rusch, Valerie W., Plitas, George, Heerdt, Alexandra S., Ladanyi, Marc, Hyman, David M., Jones, David R., Morrow, Monica, Riely, Gregory J., Scher, Howard I., Rudin, Charles M., Robson, Mark E., Diaz, Luis A., Solit, David B., Aravanis, Alexander M., Reis-Filho, Jorge S.

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Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs von Korn, Joshua M, Altshuler, David, Kuruvilla, Finny G, McCarroll, Steven A, Wysoker, Alec, Nemesh, James, Cawley, Simon, Hubbell, Earl, Veitch, Jim, Collins, Patrick J, Darvishi, Katayoon, Lee, Charles, Nizzari, Marcia M, Gabriel, Stacey B, Purcell, Shaun, Daly, Mark J

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Integrated detection and population-genetic analysis of SNPs and copy number variation von McCarroll, Steven A, Altshuler, David, Kuruvilla, Finny G, Korn, Joshua M, Cawley, Simon, Nemesh, James, Wysoker, Alec, Shapero, Michael H, de Bakker, Paul I W, Maller, Julian B, Kirby, Andrew, Elliott, Amanda L, Parkin, Melissa, Hubbell, Earl, Webster, Teresa, Mei, Rui, Veitch, James, Collins, Patrick J, Handsaker, Robert, Lincoln, Steve, Nizzari, Marcia, Blume, John, Jones, Keith W, Rava, Rich, Daly, Mark J, Gabriel, Stacey B

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Robust estimators for expression analysis von Hubbell, Earl, Liu, Wei-Min, Mei, Rui

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Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP array von Hoffmann, Thomas J., Kvale, Mark N., Hesselson, Stephanie E., Zhan, Yiping, Aquino, Christine, Cao, Yang, Cawley, Simon, Chung, Elaine, Connell, Sheryl, Eshragh, Jasmin, Ewing, Marcia, Gollub, Jeremy, Henderson, Mary, Hubbell, Earl, Iribarren, Carlos, Kaufman, Jay, Lao, Richard Z., Lu, Yontao, Ludwig, Dana, Mathauda, Gurpreet K., McGuire, William, Mei, Gangwu, Miles, Sunita, Purdy, Matthew M., Quesenberry, Charles, Ranatunga, Dilrini, Rowell, Sarah, Sadler, Marianne, Shapero, Michael H., Shen, Ling, Shenoy, Tanushree R., Smethurst, David, Van den Eeden, Stephen K., Walter, Larry, Wan, Eunice, Wearley, Reid, Webster, Teresa, Wen, Christopher C., Weng, Li, Whitmer, Rachel A., Williams, Alan, Wong, Simon C., Zau, Chia, Finn, Andrea, Schaefer, Catherine, Kwok, Pui-Yan, Risch, Neil

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Overall and non‐lung cancer incidence and mortality in the National Lung Screening Trial: Opportunities for multi‐cancer early detection von Patel, Alpa V., Chang, Ellen T., Hackshaw, Allan, Janes, Sam M., Buist, Diana S. M., Hubbell, Earl, Clarke, Christina A., Colditz, Graham A.

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Genome-wide sequencing for early stage lung cancer detection from plasma cell-free DNA (cfDNA): The Circulating Cancer Genome Atlas (CCGA) study von Oxnard, Geoffrey R., Maddala, Tara, Hubbell, Earl, Aravanis, Alex, Zhang, Nan, Venn, Oliver, Valouev, Anton, Shen, Ling, Patel, Shilpen, Jamshidi, Arash, Jagadeesh, Karthik, Gross, Samuel, Filippova, Darya, Beausang, John F., Liu, Minetta C., Richards, Donald A., Plevritis, Sylvia, Williams, Richard Thomas, Hartman, Anne-Renee, Swanton, Charles

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Prevalence of clonal hematopoiesis of indeterminate potential (CHIP) measured by an ultra-sensitive sequencing assay: Exploratory analysis of the Circulating Cancer Genome Atlas (C... von Swanton, Charles, Venn, Oliver, Aravanis, Alex, Hubbell, Earl, Maddala, Tara, Beausang, John F., Filippova, Darya, Gross, Samuel, Jamshidi, Arash, Shen, Ling, Valouev, Anton, Zhang, Nan, Bolton, Kelly L, Yeatman, Timothy Joseph, Seiden, Michael, Oxnard, Geoffrey R., Liu, Minetta C., Williams, Richard Thomas, Hartman, Anne-Renee, Baselga, Jose

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Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome von Wang, David G., Fan, Jian-Bing, Siao, Chia-Jen, Berno, Anthony, Young, Peter, Sapolsky, Ron, Ghandour, Ghassan, Perkins, Nancy, Winchester, Ellen, Spencer, Jessica, Kruglyak, Leonid, Stein, Lincoln, Hsie, Linda, Topaloglou, Thodoros, Hubbell, Earl, Robinson, Elizabeth, Mittmann, Michael, Morris, Macdonald S., Shen, Naiping, Kilburn, Dan, Rioux, John, Nusbaum, Chad, Rozen, Steve, Hudson, Thomas J., Lipshutz, Robert, Chee, Mark, Lander, Eric S.

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Resolving deconvolution ambiguity in gene alternative splicing von She, Yiyuan, Hubbell, Earl, Wang, Hui

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Modeled Reductions in Late-stage Cancer with a Multi-Cancer Early Detection Test von Hubbell, Earl, Clarke, Christina A, Aravanis, Alexander M, Berg, Christine D

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Abstract 2239: Detecting cancer when it can be cured: The potential for cure across all stageable cancers von Hubbell, Earl, Clarke, Christina

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Probe Selection for High-Density Oligonucleotide Arrays von Mei, Rui, Hubbell, Earl, Bekiranov, Stefan, Mittmann, Mike, Christians, Fred C., Shen, Mei-Mei, Lu, Gang, Fang, Joy, Liu, Wei-Min, Ryder, Tom, Kaplan, Paul, Kulp, David, Webster, Teresa A.

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Modelled mortality benefits of multi-cancer early detection screening in England von Sasieni, Peter, Smittenaar, Rebecca, Hubbell, Earl, Broggio, John, Neal, Richard D., Swanton, Charles

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Correction: Modelled mortality benefits of multi-cancer early detection screening in England von Sasieni, Peter, Smittenaar, Rebecca, Hubbell, Earl, Broggio, John, Neal, Richard D., Swanton, Charles

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Multi-cancer early detection: A new paradigm for reducing cancer-specific and all-cause mortality von Clarke, Christina A., Hubbell, Earl, Ofman, Joshua J.

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Gene structure-based splice variant deconvolution using a microarry platform von Wang, Hui, Hubbell, Earl, Hu, Jing-shan, Mei, Gangwu, Cline, Melissa, Lu, Gang, Clark, Tyson, Siani-Rose, Michael A., Ares, Manuel, Kulp, David C., Haussler, David

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Modeled residual current cancer risk after clinical investigation of a positive multicancer early detection test result von Hudnut, Andrew G., Hubbell, Earl, Venn, Oliver, Church, Timothy R.

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Multicancer Early Detection von Chang, Ellen T, Hubbell, Earl, Klein, Eric A

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