An ingestible self-orienting system for oral delivery of macromolecules von Abramson, Alex, Caffarel-Salvador, Ester, Khang, Minsoo, Dellal, David, Silverstein, David, Gao, Yuan, Frederiksen, Morten Revsgaard, Vegge, Andreas, Hubálek, František, Water, Jorrit J., Friderichsen, Anders V., Fels, Johannes, Kirk, Rikke Kaae, Cleveland, Cody, Collins, Joy, Tamang, Siddartha, Hayward, Alison, Landh, Tomas, Buckley, Stephen T., Roxhed, Niclas, Rahbek, Ulrik, Langer, Robert, Traverso, Giovanni

Volltext

Binding of Rasagiline-Related Inhibitors to Human Monoamine Oxidases:  A Kinetic and Crystallographic Analysis von Binda, Claudia, Hubálek, Frantisek, Li, Min, Herzig, Yaacov, Sterling, Jeffrey, Edmondson, Dale E, Mattevi, Andrea

Volltext

Additional disulfide bonds in insulin: Prediction, recombinant expression, receptor binding affinity, and stability von Vinther, Tine N, Pettersson, Ingrid, Huus, Kasper, Schlein, Morten, Steensgaard, Dorte B, Sørensen, Anders, Jensen, Knud J, Kjeldsen, Thomas, Hubalek, František

Volltext

Crystal Structures of Monoamine Oxidase B in Complex with Four Inhibitors of the N-Propargylaminoindan Class von Binda, Claudia, Hubálek, Frantisek, Li, Min, Herzig, Yaacov, Sterling, Jeffrey, Edmondson, Dale E, Mattevi, Andrea

Volltext

Molecular engineering of safe and efficacious oral basal insulin von Hubálek, Frantisek, Refsgaard, Hanne H. F., Gram-Nielsen, Sanne, Madsen, Peter, Nishimura, Erica, Münzel, Martin, Brand, Christian Lehn, Stidsen, Carsten Enggaard, Claussen, Christian Hove, Wulff, Erik Max, Pridal, Lone, Ribel, Ulla, Kildegaard, Jonas, Porsgaard, Trine, Johansson, Eva, Steensgaard, Dorte Bjerre, Hovgaard, Lars, Glendorf, Tine, Hansen, Bo Falck, Jensen, Maja Kirkegaard, Nielsen, Peter Kresten, Ludvigsen, Svend, Rugh, Susanne, Garibay, Patrick W., Moore, Mary Courtney, Cherrington, Alan D., Kjeldsen, Thomas

Volltext

Structural characterization of insulin NPH formulations von Norrman, Mathias, Hubálek, Frantisek, Schluckebier, Gerd

Volltext

Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane von Binda, Claudia, Hubálek, Frantisek, Li, Min, Edmondson, Dale E., Mattevi, Andrea

Volltext

Dually Reactive Long Recombinant Linkers for Bioconjugations as an Alternative to PEG von Kjeldsen, Thomas, Hogendorf, Wouter F. J, Tornøe, Christian W, Anderson, Jonathan, Hubalek, Frantisek, Stidsen, Carsten E, Sorensen, Jan L, Hoeg-Jensen, Thomas

Volltext

WD40 Repeat Proteins Striatin and S/G2 Nuclear Autoantigen Are Members of a Novel Family of Calmodulin-binding Proteins That Associate with Protein Phosphatase 2A von Moreno, Carlos S., Park, Susan, Nelson, Kasey, Ashby, Danita, Hubalek, Frantisek, Lane, William S., Pallas, David C.

Volltext

Inactivation of Purified Human Recombinant Monoamine Oxidases A and B by Rasagiline and Its Analogues von Hubálek, Frantisek, Binda, Claudia, Li, Min, Herzig, Yaacov, Sterling, Jeffrey, Youdim, Moussa B. H, Mattevi, Andrea, Edmondson, Dale E

Volltext

Insights into the Mode of Inhibition of Human Mitochondrial Monoamine Oxidase B from High-Resolution Crystal Structures von Binda, Claudia, Li, Min, Hubálek, Frantisek, Restelli, Nadia, Edmondson, Dale E., Mattevi, Andrea

Volltext

Demonstration of Isoleucine 199 as a Structural Determinant for the Selective Inhibition of Human Monoamine Oxidase B by Specific Reversible Inhibitors von Hubálek, Frantisek, Binda, Claudia, Khalil, Ashraf, Li, Min, Mattevi, Andrea, Castagnoli, Neal, Edmondson, Dale E.

Volltext

2032-LB: In Vivo Chain Splitting of Human Insulin von Sturis, Jeppe, Cramer, Christian, Brand, Christian L, Helleberg, Hans, Kurtzhals, Peter, Hubalek, Frantisek

Volltext

815-P: Enhanced Disulphide Bond Stability Contributes to the Once Weekly PD Profile of Insulin Icodec von HUBALEK, FRANTISEK, CRAMER, CHRISTIAN, HELLEBERG, HANS, JOHANSSON, EVA, SCHLUCKEBIER, GERD, STEENSGAARD, DORTE B., STURIS, JEPPE, KJELDSEN, THOMAS

Volltext

Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders von Edmondson, Dale E, Mattevi, Andrea, Binda, Claudia, Newton-Vinson, Paige, Hubálek, Frantisek

Volltext

Author Correction: Molecular engineering of safe and efficacious oral basal insulin von Hubálek, Frantisek, Refsgaard, Hanne H. F., Gram-Nielsen, Sanne, Madsen, Peter, Nishimura, Erica, Münzel, Martin, Brand, Christian Lehn, Stidsen, Carsten Enggaard, Claussen, Christian Hove, Wulff, Erik Max, Pridal, Lone, Ribel, Ulla, Kildegaard, Jonas, Porsgaard, Trine, Johansson, Eva, Steensgaard, Dorte Bjerre, Hovgaard, Lars, Glendorf, Tine, Hansen, Bo Falck, Jensen, Maja Kirkegaard, Nielsen, Peter Kresten, Ludvigsen, Svend, Rugh, Susanne, Garibay, Patrick W., Moore, Mary Courtney, Cherrington, Alan D., Kjeldsen, Thomas

Volltext

Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans von Kjeldsen, Thomas B, Hubálek, František, Hjørringgaard, Claudia U, Tagmose, Tina M, Nishimura, Erica, Stidsen, Carsten E, Porsgaard, Trine, Fledelius, Christian, Refsgaard, Hanne H. F, Gram-Nielsen, Sanne, Naver, Helle, Pridal, Lone, Hoeg-Jensen, Thomas, Jeppesen, Claus Bekker, Manfè, Valentina, Ludvigsen, Svend, Lautrup-Larsen, Inger, Madsen, Peter

Volltext

Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors von Abramson, Alex, Frederiksen, Morten Revsgaard, Vegge, Andreas, Jensen, Brian, Poulsen, Mette, Mouridsen, Brian, Jespersen, Mikkel Oliver, Kirk, Rikke Kaae, Windum, Jesper, Hubálek, František, Water, Jorrit J., Fels, Johannes, Gunnarsson, Stefán B., Bohr, Adam, Straarup, Ellen Marie, Ley, Mikkel Wennemoes Hvitfeld, Lu, Xiaoya, Wainer, Jacob, Collins, Joy, Tamang, Siddartha, Ishida, Keiko, Hayward, Alison, Herskind, Peter, Buckley, Stephen T., Roxhed, Niclas, Langer, Robert, Rahbek, Ulrik, Traverso, Giovanni

Volltext

Chemo- and Regioselective Ethynylation of Tryptophan-Containing Peptides and Proteins von Hansen, Morten Borre, Hubálek, František, Skrydstrup, Troels, Hoeg-Jensen, Thomas

Volltext

Investigation of the Physico-Chemical Properties that Enable Co-Formulation of Basal Insulin Degludec with Fast-Acting Insulin Aspart von Havelund, Svend, Ribel, Ulla, Hubálek, František, Hoeg-Jensen, Thomas, Wahlund, Per-Olof, Jonassen, Ib

Volltext