In Vitro and In Silico Biological Studies of 4-Phenyl-2-quinolone (4-PQ) Derivatives as Anticancer Agents von Chen, Yi-Fong, Lawal, Bashir, Huang, Li-Jiau, Kuo, Sheng-Chu, Sumitra, Maryam Rachmawati, Mokgautsi, Ntlotlang, Lin, Hung-Yun, Huang, Hsu-Shan

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Design, Synthesis, and Preclinical Evaluation of New 5,6- (or 6,7-) Disubstituted-2-(fluorophenyl)quinolin-4-one Derivatives as Potent Antitumor Agents von Chou, Li-Chen, Tsai, Meng-Tung, Hsu, Mei-Hua, Wang, Sheng-Hung, Way, Tzong-Der, Huang, Chi-Hung, Lin, Hui-Yi, Qian, Keduo, Dong, Yizhou, Lee, Kuo-Hsiung, Huang, Li-Jiau, Kuo, Sheng-Chu

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YC‐1 inhibits proliferation of breast cancer cells by down‐regulating EZH2 expression via activation of c‐Cbl and ERK von Chang, Ling‐Chu, Lin, Hui‐Yi, Tsai, Meng‐Tung, Chou, Ruey‐Hwang, Lee, Fang‐Yu, Teng, Che‐Ming, Hsieh, Min‐Tsang, Hung, Hsin‐Yi, Huang, Li‐Jiau, Yu, Yung‐Luen, Kuo, Sheng‐Chu

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Synthesis and SAR studies of novel 6,7,8‐substituted 4‐substituted benzyloxyquinolin‐2(1H)‐one derivatives for anticancer activity von Chen, Yi‐Fong, Lin, Yi‐Chien, Morris‐Natschke, Susan L, Wei, Chen‐Fang, Shen, Ting‐Chen, Lin, Hui‐Yi, Hsu, Mei‐Hua, Chou, Li‐Chen, Zhao, Yu, Kuo, Sheng‐Chu, Lee, Kuo‐Hsiung, Huang, Li‐Jiau

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Ginger and Its Bioactive Component Inhibit Enterotoxigenic Escherichia coli Heat-Labile Enterotoxin-Induced Diarrhea in Mice von Chen, Jaw-Chyun, Huang, Li-Jiau, Wu, Shih-Lu, Kuo, Sheng-Chu, Ho, Tin-Yun, Hsiang, Chien-Yun

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Three new clerodane diterpenes from Polyalthia longifolia var. pendula von Wu, Tung-Ho, Cheng, Yung-Yi, Chen, Chao-Jung, Ng, Lean-Teik, Chou, Li-Chen, Huang, Li-Jiau, Chen, Yung-Husan, Kuo, Sheng-Chu, El-Shazly, Mohamed, Wu, Yang-Chang, Chang, Fang-Rong, Liaw, Chih-Chuang

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The anti‐inflammatory carbazole, LCY‐2‐CHO, inhibits lipopolysaccharide‐induced inflammatory mediator expression through inhibition of the p38 mitogen‐activated protein kinase sign... von Ho, Feng‐Ming, Lai, Chih‐Chang, Huang, Li‐Jiau, Kuo, Tsun Cheng, Chao, Chien M, Lin, Wan‐Wan

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Novel quinolone CHM-1 induces apoptosis and inhibits metastasis in a human osterogenic sarcoma cell line von Hsu, Shu-Chun, Yang, Jai-Sing, Kuo, Chao-Lin, Lo, Chyi, Lin, Jing-Pin, Hsia, Te-Chun, Lin, Jen-Jyh, Lai, Kuang-Chi, Kuo, Hsiu-Maan, Huang, Li-Jiau, Kuo, Sheng-Chu, Wood, W. Gibson, Chung, Jing-Gung

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synthesized 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one (CHM-1) promoted G2/M arrest through inhibition of CDK1 and induced apoptosis through the mitochondrial-dependent pa... von Chou, Li-Chen, Yang, Jai-Sing, Huang, Li-Jiau, Wu, Hsi-Chin, Lu, Chi-Cheng, Chiang, Jo-Hua, Chen, Kuan-Tin, Kuo, Sheng-Chu, Chung, Jing-Gung

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Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226 von Chen, Chun-Jen, Hsu, Mei-Hua, Huang, Li-Jiau, Yamori, Takao, Chung, Jing-Gung, Lee, Fang-Yu, Teng, Che-Ming, Kuo, Sheng-Chu

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Inhibition of nitric oxide production by the carbazole compound LCY-2-CHO via blockade of activator protein-1 and CCAAT/enhancer-binding protein activation in microglia von Chang, Ling-Chu, Tsao, Lo-Ti, Chang, Chi-Sen, Chen, Chun-Jung, Huang, Li-Jiau, Kuo, Sheng-Chu, Lin, Ruey-Hseng, Wang, Jih-Pyang

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Proteomic approach to studying the cytotoxicity of YC-1 on U937 leukemia cells and antileukemia activity in orthotopic model of leukemia mice von Chung, Jing-Gung, Yang, Jai-Sing, Huang, Li-Jiau, Lee, Fang-Yu, Teng, Che-Ming, Tsai, Sheng-Chung, Lin, Kuei-Li, Wang, Shu-Fang, Kuo, Sheng-Chu

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Neuroprotective Effects of Ugonin K on Hydrogen Peroxide-Induced Cell Death in Human Neuroblastoma SH-SY5Y Cells von Lin, Yi-Chien, Huang, Yaun-Chao, Chen, Sheng-Chih, Liaw, Chih-Chuang, Kuo, Sheng-Chu, Huang, Li-Jiau, Gean, Po-Wu

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Signaling mechanisms of inhibition of phospholipase D activation by CHS-111 in formyl peptide-stimulated neutrophils von Chang, Ling-Chu, Huang, Tai-Hung, Chang, Chi-Sen, Tsai, Ya-Ru, Lin, Ruey-Hseng, Lee, Pin-Wen, Hsu, Mei-Feng, Huang, Li-Jiau, Wang, Jih-Pyang

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Synthesis and antiplatelet activity of ethyl 4-(1-benzyl-1 H-indazol-3-yl)benzoate (YD-3) derivatives von Chen, Hua-Sin, Kuo, Sheng-Chu, Teng, Che-Ming, Lee, Fang-Yu, Wang, Jih-Pyang, Lee, Yu-Chun, Kuo, Chiung-Wen, Huang, Ching-Che, Wu, Chin-Chung, Huang, Li-Jiau

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Mechanistic studies on regioselective dephosphorylation of phosphate prodrugs during a facile synthesis of antitumor phosphorylated 2-phenyl-6,7-methylenedioxy-1H-quinolin-4-one von Cheng, Yung-Yi, Liu, Chin-Yu, Huang, Li-Jiau, Huang, Chi-Hung, Lee, Kuo-Hsiung, Lin, Cheng-Tung, Kuo, Sheng-Chu

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(-)-Epigallocatechin Gallate Induced Apoptosis in Human Adrenal Cancer NCI-H295 Cells through Caspase-dependent and Caspase-independent Pathway von WU, Ping-Ping, KUO, Sheng-Chu, HUANG, Wen-Wen, YANG, Jai-Sing, LAI, Kuang-Chi, CHEN, Hui-Jye, LIN, Kuei-Li, CHIU, Yu-Jen, HUANG, Li-Jiau, CHUNG, Jing-Gung

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Geraniin-mediated apoptosis by cleavage of focal adhesion kinase through up-regulation of Fas ligand expression in human melanoma cells von Lee, Jang-Chang, Tsai, Chih-Yen, Kao, Jung-Yie, Kao, Ming-Ching, Tsai, Shih-Chang, Chang, Chih-Shiang, Huang, Li-Jiau, Kuo, Sheng-Chu, Lin, Jen-Kun, Way, Tzong-Der

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Synthesis and antitumor activity of bis(hydroxymethyl)propionate analogs of pterostilbene in cisplatin-resistant human oral cancer cells von Hsieh, Min-Tsang, Huang, Li-Jiau, Wu, Tian-Shung, Lin, Hui-Yi, Morris-Natschke, Susan L., Lee, Kuo-Hsiung, Kuo, Sheng-Chu

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Synthesis and biological relationships of 3′,6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents von Lai, Ya-Yun, Huang, Li-Jiau, Lee, Kuo-Hsiung, Xiao, Zhiyan, Bastow, Kenneth F., Yamori, Takao, Kuo, Sheng-Chu

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