Structure of an E6AP-UbcH7 Complex: Insights into Ubiquitination by the E2- E3 Enzyme Cascade von Huang, Lan, Kinnucan, Elspeth, Wang, Guangli, Beaudenon, Sylvie, Howley, Peter M., Huibregtse, Jon M., Pavletich, Nikola P.

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In vivo ubiquitination and proteasome-mediated degradation of p53 von MAKI, C. G, HUIBREGTSE, J. M, HOWLEY, P. M

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Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53 von HUIBREGTSE, J. M, SCHEFFNER, M, HOWLEY, P. M

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 von Scheffner, Martin, Huibregtse, Jon M., Vierstra, Richard D., Howley, Peter M.

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A Family of Proteins Structurally and Functionally Related to the E6-AP Ubiquitin-Protein Ligase von Huibregtse, Jon M., Scheffner, Martin, Beaudenon, Sylvie, Howley, Peter M.

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Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation von Maki, Carl G., Howley, Peter M.

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The State of the p53 and Retinoblastoma Genes in Human Cervical Carcinoma Cell Lines von Scheffner, Martin, Munger, Karl, Byrne, Janet C., Howley, Peter M.

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Human papillomavirus immortalization and transformation functions von Münger, Karl, Howley, Peter M

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Chronic Estrogen-Induced Cervical and Vaginal Squamous Carcinogenesis in Human Papillomavirus Type 16 Transgenic Mice von Arbeit, Jeffrey M., Howley, Peter M., Hanahan, Douglas

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Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice von ARBEIT, J. M, MÜNGER, K, HOWLEY, P. M, HANAHAN, D

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Mutations in serines 15 and 20 of human p53 impair its apoptotic activity von UNGER, T, SIONOV, R. V, MOALLEM, E, YEE, C. L, HOWLEY, P. M, OREN, M, HAUPT, Y

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Adenovirus E1A, Simian Virus 40 Tumor Antigen, and Human Papillomavirus E7 Protein Share the Capacity to Disrupt the Interaction Between Transcription Factor E2F and the Retinoblas... von Chellappan, Srikumar, Kraus, Virginia B., Kroger, Burkhard, Munger, Karl, Howley, Peter M., Nevins, Joseph R.

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Interaction of the Bovine Papillomavirus E2 Protein with Brd4 Tethers the Viral DNA to Host Mitotic Chromosomes von You, Jianxin, Croyle, Jennie L, Nishimura, Akiko, Ozato, Keiko, Howley, Peter M

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The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes von MÜNGER, K, PHELPS, W. C, BUBB, V, HOWLEY, P. M, SCHLEGEL, R

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Identification of a Human Ubiquitin-Conjugating Enzyme that Mediates the E6-AP-Dependent Ubiquitination of p53 von Scheffner, Martin, Huibregtse, Jon M., Howley, Peter M.

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Disruption of Either the E1 or the E2 Regulatory Gene of Human Papillomavirus Type 16 Increases Viral Immortalization Capacity von Romanczuk, Helen, Howley, Peter M.

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Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins von Huibregtse, J M, Scheffner, M, Howley, P M

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Efficiency of Binding the Retinoblastoma Protein Correlates with the Transforming Capacity of the E7 Oncoproteins of the Human Papillomaviruses von Heck, Donald V., Yee, Carole L., Howley, Peter M., Munger, Karl

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Inhibition of Cyclin D-CDK4/CDK6 Activity is Associated with an E2F-Mediated Induction of Cyclin Kinase Inhibitor Activity von Khleif, Samir N., DeGregori, James, Yee, Carole L., Otterson, Gregory A., Kaye, Frederic J., Nevins, Joseph R., Howley, Peter M.

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Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53 von Werness, Bruce A., Levine, Arnold J., Howley, Peter M.

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