The identification of a selective dopamine D2 partial agonist, D3 antagonist displaying high levels of brain exposure von HOLMES, Ian P, BLUNT, Richard J, HOWES, Claire M, MICHELI, Fabrizio, DI FABIO, Romano, DONATI, Daniele, TERRENI, Silvia, HAMPRECHT, Dieter, ARISTA, Luca, WORBY, Angela, WATSON, Steve P, LORTHIOIR, Olivier E, BLOWERS, Stephen M, GRIBBLE, Andy, PAYNE, Andrew H, STANSFIELD, Ian G, WOOD, Martyn, WOOLLARD, Patrick M, REAVILL, Charlie

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The identification of a selective dopamine D 2 partial agonist, D 3 antagonist displaying high levels of brain exposure von Holmes, Ian P., Blunt, Richard J., Lorthioir, Olivier E., Blowers, Stephen M., Gribble, Andy, Payne, Andrew H., Stansfield, Ian G., Wood, Martyn, Woollard, Patrick M., Reavill, Charlie, Howes, Claire M., Micheli, Fabrizio, Fabio, Romano Di, Donati, Daniele, Terreni, Silvia, Hamprecht, Dieter, Arista, Luca, Worby, Angela, Watson, Steve P.

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The identification of a selective dopamine D sub(2) partial agonist, D sub(3) antagonist displaying high levels of brain exposure von Holmes, Ian P, Blunt, Richard J, Lorthioir, Olivier E, Blowers, Stephen M, Gribble, Andy, Payne, Andrew H, Stansfield, Ian G, Wood, Martyn, Woollard, Patrick M, Reavill, Charlie, Howes, Claire M, Micheli, Fabrizio, Di Fabio, Romano, Donati, Daniele, Terreni, Silvia, Hamprecht, Dieter, Arista, Luca, Worby, Angela, Watson, Steve P

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Future directions for the discovery of natural product-derived immunomodulating drugs: an IUPHAR positional review von Wainwright, Cherry L., Teixeira, Mauro M., Adelson, David L., Braga, Fernão C., Buenz, Eric J., Campana, Priscilla R.V., David, Bruno, Glaser, Keith B., Harata-Lee, Yuka, Howes, Melanie-Jayne R., Izzo, Angelo A., Maffia, Pasquale, Mayer, Alejandro M.S., Mazars, Claire, Newman, David J., Nic Lughadha, Eimear, Pádua, Rodrigo M., Pimenta, Adriano M.C., Parra, John A.A., Qu, Zhipeng, Shen, Hanyuan, Spedding, Michael, Wolfender, Jean-Luc

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Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration von Scott, Gregory, Zetterberg, Henrik, Jolly, Amy, Cole, James H, De Simoni, Sara, Jenkins, Peter O, Feeney, Claire, Owen, David R, Lingford-Hughes, Anne, Howes, Oliver, Patel, Maneesh C, Goldstone, Anthony P, Gunn, Roger N, Blennow, Kaj, Matthews, Paul M, Sharp, David J

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Post-polymerisation functionalisation of conjugated polymer backbones and its application in multi-functional emissive nanoparticles von Creamer, Adam, Wood, Christopher S., Howes, Philip D., Casey, Abby, Cong, Shengyu, Marsh, Adam V., Godin, Robert, Panidi, Julianna, Anthopoulos, Thomas D., Burgess, Claire H., Wu, Tingman, Fei, Zhuping, Hamilton, Iain, McLachlan, Martyn A., Stevens, Molly M., Heeney, Martin

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Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-i... von Liu, Xinxue, Shaw, Robert H, Stuart, Arabella S V, Greenland, Melanie, Aley, Parvinder K, Andrews, Nick J, Cameron, J Claire, Charlton, Sue, Clutterbuck, Elizabeth A, Collins, Andrea M, Dinesh, Tanya, England, Anna, Faust, Saul N, Ferreira, Daniela M, Finn, Adam, Green, Christopher A, Hallis, Bassam, Heath, Paul T, Hill, Helen, Lambe, Teresa, Lazarus, Rajeka, Libri, Vincenzo, Long, Fei, Mujadidi, Yama F, Plested, Emma L, Provstgaard-Morys, Samuel, Ramasamy, Maheshi N, Ramsay, Mary, Read, Robert C, Robinson, Hannah, Singh, Nisha, Turner, David P J, Turner, Paul J, Walker, Laura L, White, Rachel, Nguyen-Van-Tam, Jonathan S, Snape, Matthew D, Munro, Alasdair P S, Bartholomew, Jazz, Presland, Laura, Horswill, Sarah, Warren, Sarah, Varkonyi-Clifford, Sophie, Saich, Stephen, Adams, Kirsty, Ricamara, Marivic, Turner, Nicola, Yee Ting, Nicole Y, Whittley, Sarah, Rampling, Tommy, Desai, Amisha, Brown, Claire H, Qureshi, Ehsaan, Gokani, Karishma, Naker, Kush, Kellett Wright, Johanna K, Williams, Rachel L, Riaz, Tawassal, Penciu, Florentina D, Di Maso, Claudio, Howe, Elizabeth G, Vichos, Iason, Ghulam Farooq, Mujtaba, Noristani, Rabiullah, Yao, Xin L, Oldfield, Neil J, Hammersley, Daniel, Belton, Sue, Royal, Simon, San Francisco Ramos, Alberto, Hultin, Cecilia, Galiza, Eva P, Shiham, Farah, Solórzano, Carla, Sainsbury, Hannah, Davies, Kelly, Ambrose, Pauline, Hitchins, Lisa, Baker, Natalie, Leung, Stephanie, Fothergill, Ross, Godwin, Kerry, Buttigieg, Karen, Shaik, Imam, Brown, Phill, Knight, Chanice, Lall, Paminder, Allen, Lauren

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Alliance of Genome Resources Portal: unified model organism research platform von Agapite, Julie, Albou, Laurent-Philippe, Aleksander, Suzi, Argasinska, Joanna, Arnaboldi, Valerio, Attrill, Helen, Bello, Susan M., Blake, Judith A., Blodgett, Olin, Bradford, Yvonne M., Bult, Carol J., Cain, Scott, Calvi, Brian R., Carbon, Seth, Chan, Juancarlos, Chen, Wen J., Cherry, J. Michael, Cho, Jaehyoung, Christie, Karen R., Crosby, Madeline A., De Pons, Jeff, Dolan, Mary E., dos Santos, Gilberto, Dunn, Barbara Dunn Nathan, Eagle, Anne, Ebert, Dustin, Engel, Stacia R., Fashena, David, Frazer, Ken, Gao, Sibyl, Gondwe, Felix, Goodman, Josh, Gramates, L. Sian, Grove, Christian A., Harris, Todd, Harrison, Marie-Claire, Howe, Douglas G., Howe, Kevin L., Jha, Sagar, Kadin, James A., Kaufman, Thomas C., Kalita, Patrick, Karra, Kalpana, Kishore, Ranjana, Laulederkind, Stan, Lee, Raymond, MacPherson, Kevin A., Marygold, Steven J., Matthews, Beverley, Millburn, Gillian, Miyasato, Stuart, Moxon, Sierra, Mueller, Hans-Michael, Mungall, Christopher, Muruganujan, Anushya, Mushayahama, Tremayne, Nash, Robert S., Ng, Patrick, Paulini, Michael, Perrimon, Norbert, Pich, Christian, Raciti, Daniela, Richardson, Joel E., Russell, Matthew, Gelbart, Susan Russo, Ruzicka, Leyla, Schaper, Kevin, Shimoyama, Mary, Simison, Matt, Smith, Cynthia, Shaw, David R., Shrivatsav, Ajay, Skrzypek, Marek, Smith, Jennifer R., Sternberg, Paul W., Tabone, Christopher J., Thomas, Paul D., Thota, Jyothi, Toro, Sabrina, Tomczuk, Monika, Tutaj, Marek, Tutaj, Monika, Urbano, Jose-Maria, Van Auken, Kimberly, Van Slyke, Ceri E., Wang, Shur-Jen, Weng, Shuai, Westerfield, Monte, Williams, Gary, Wong, Edith D., Wright, Adam, Yook, Karen

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Individual and combined effects of cannabidiol and Δ9-tetrahydrocannabinol on striato-cortical connectivity in the human brain von Wall, Matthew B, Freeman, Tom P, Hindocha, Chandni, Demetriou, Lysia, Ertl, Natalie, Freeman, Abigail M, Jones, Augustus PM, Lawn, Will, Pope, Rebecca, Mokrysz, Claire, Solomons, Daniel, Statton, Ben, Walker, Hannah R, Yamamori, Yumeya, Yang, Zixu, Yim, Jocelyn LL, Nutt, David J, Howes, Oliver D, Curran, H Valerie, Bloomfield, Michael AP

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Corrigendum to “Future directions for the discovery of natural product-derived immunomodulating drugs: An IUPHAR positional review” [Pharmacol. Res. 177 (2022) 106076] von Wainwright, Cherry L., Teixeira, Mauro M., Adelson, David L., Buenz, Eric J., David, Bruno, Glaser, Keith B., Harata-Lee, Yuka, Howes, Melanie-Jayne R., Izzo, Angelo A., Maffia, Pasquale, Mayer, Alejandro M.S., Mazars, Claire, Newman, David J., Lughadha, Eimear Nic, Pimenta, Adriano M.C., Parra, John A.A., Qu, Zhipeng, Shen, Hanyuan, Spedding, Michael, Wolfender, Jean-Luc

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Placebo effects in randomized trials of pharmacological and neurostimulation interventions for mental disorders: An umbrella review von Huneke, Nathan T M, Amin, Jay, Baldwin, David S, Bellato, Alessio, Brandt, Valerie, Chamberlain, Samuel R, Correll, Christoph U, Eudave, Luis, Garner, Matthew, Gosling, Corentin J, Hill, Catherine M, Hou, Ruihua, Howes, Oliver D, Ioannidis, Konstantinos, Köhler-Forsberg, Ole, Marzulli, Lucia, Reed, Claire, Sinclair, Julia M A, Singh, Satneet, Solmi, Marco, Cortese, Samuele

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Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error von Tedja, Milly S., Wojciechowski, Robert, Hysi, Pirro G., Eriksson, Nicholas, Furlotte, Nicholas A., Verhoeven, Virginie J. M., Iglesias, Adriana I., Meester-Smoor, Magda A., Tompson, Stuart W., Fan, Qiao, Khawaja, Anthony P., Cheng, Ching-Yu, Höhn, René, Yamashiro, Kenji, Wenocur, Adam, Grazal, Clare, Haller, Toomas, Metspalu, Andres, Wedenoja, Juho, Jonas, Jost B., Wang, Ya Xing, Xie, Jing, Mitchell, Paul, Foster, Paul J., Klein, Barbara E. K., Klein, Ronald, Paterson, Andrew D., Hosseini, S. Mohsen, Shah, Rupal L., Williams, Cathy, Teo, Yik Ying, Tham, Yih Chung, Gupta, Preeti, Zhao, Wanting, Shi, Yuan, Saw, Woei-Yuh, Tai, E-Shyong, Sim, Xue Ling, Huffman, Jennifer E., Polašek, Ozren, Hayward, Caroline, Bencic, Goran, Rudan, Igor, Wilson, James F., Joshi, Peter K., Tsujikawa, Akitaka, Matsuda, Fumihiko, Whisenhunt, Kristina N., Zeller, Tanja, van der Spek, Peter J., Haak, Roxanna, Meijers-Heijboer, Hanne, van Leeuwen, Elisabeth M., Iyengar, Sudha K., Lass, Jonathan H., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, André G., Vingerling, Johannes R., Lehtimäki, Terho, Raitakari, Olli T., Biino, Ginevra, Concas, Maria Pina, Schwantes-An, Tae-Hwi, Igo, Robert P., Cuellar-Partida, Gabriel, Martin, Nicholas G., Craig, Jamie E., Gharahkhani, Puya, Williams, Katie M., Nag, Abhishek, Rahi, Jugnoo S., Cumberland, Phillippa M., Delcourt, Cécile, Bellenguez, Céline, Ried, Janina S., Bergen, Arthur A., Meitinger, Thomas, Gieger, Christian, Wong, Tien Yin, Hewitt, Alex W., Mackey, David A., Simpson, Claire L., Pfeiffer, Norbert, Pärssinen, Olavi, Baird, Paul N., Vitart, Veronique, Amin, Najaf, van Duijn, Cornelia M., Bailey-Wilson, Joan E., Young, Terri L., Saw, Seang-Mei, Stambolian, Dwight, MacGregor, Stuart, Guggenheim, Jeremy A., Tung, Joyce Y., Hammond, Christopher J., Klaver, Caroline C. W.

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Trace amine-associated receptor 1 (TAAR1) agonists for psychosis: protocol for a living systematic review and meta-analysis of human and non-human studies von Siafis, Spyridon, McCutcheon, Robert, Chiocchia, Virginia, Ostinelli, Edoardo G, Wright, Simonne, Stansfield, Claire, Juma, Damian Omari, Mantas, Ioannis, Howes, Oliver D, Rutigliano, Grazia, Ramage, Fiona, Tinsdeall, Francesca, Friedrich, Claire, Milligan, Lea, Moreno, Carmen, Elliott, Julian H, Thomas, James, Macleod, Malcolm R, Sena, Emily S, Seedat, Soraya, Salanti, Georgia, Potts, Jennifer, Cipriani, Andrea, Leucht, Stefan

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Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial von Nichol, Alistair, Prof, French, Craig, Dr, Little, Lorraine, MBioethics, Haddad, Samir, MD, Presneill, Jeffrey, PhD, Arabi, Yaseen, MD, Bailey, Michael, PhD, Cooper, D James, Prof, Duranteau, Jacques, Prof, Huet, Olivier, Prof, Mak, Anne, BScPharm, McArthur, Colin, MBChB, Pettilä, Ville, Prof, Skrifvars, Markus, PhD, Vallance, Shirley, MPH, Varma, Dinesh, MBBS, Wills, Judy, DMU, Bellomo, Rinaldo, Prof

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Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission von Aggarwal, Dinesh, Warne, Ben, Jahun, Aminu S., Hamilton, William L., Fieldman, Thomas, du Plessis, Louis, Hill, Verity, Blane, Beth, Watkins, Emmeline, Wright, Elizabeth, Hall, Grant, Ludden, Catherine, Myers, Richard, Hosmillo, Myra, Chaudhry, Yasmin, Pinckert, Malte L., Georgana, Iliana, Izuagbe, Rhys, Leek, Danielle, Nsonwu, Olisaeloka, Hughes, Gareth J., Packer, Simon, Page, Andrew J., Metaxaki, Marina, Fuller, Stewart, Weale, Gillian, Holgate, Jon, Brown, Christopher A., Howes, Rob, McFarlane, Duncan, Dougan, Gordon, Pybus, Oliver G., Angelis, Daniela De, Maxwell, Patrick H., Peacock, Sharon J., Weekes, Michael P., Illingworth, Chris, Harrison, Ewan M., Matheson, Nicholas J., Goodfellow, Ian G.

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Subacromial balloon spacer for irreparable rotator cuff tears of the shoulder (START:REACTS): a group-sequential, double-blind, multicentre randomised controlled trial von Metcalfe, Andrew, Parsons, Nicholas, Gemperlé Mannion, Elke, Hutchinson, Charles, Lawrence, Tom, Drew, Stephen, Arif, Azra, Bush, Howard, Drew, Stephen, Fox, Jo, Gemperlé Mannion, Elke, Haque, Aminul, Kearney, Rebecca, Lawrence, Thomas, Mason, James, Modi, Chetan, Rahman, Bushra, Ramirez, Maria, Spocinska, Marta, Teuke, Joanna, Viswanath, Aparna, Underwood, Martin, Packham, Iain, Barnett, Elizabeth, Morley, Josephine, Barnfield, Stephen, Halliday, Ruth, Dunn, Sarah, Dacombe, Peter, Wilson, Deborah, Liow, Raymond, Meddes, Andrea, Kang, Niel, Nacorda, Aileen, Punnoose, Anuj, Ferran, Nicholas, Adedoyin, Temi, Sala, Matthew, Zaman, Tariq, Hartley, Richard, a-Sayyad, Charif, Vamplew, Luke, Bokor, Norbert, Moverley, Robert, Jones, Michael, Wood, Diane, Perry, Jess, Lewis, Alison, Beesley, Kate, Harries, Luke, Wilcocks, Katherine, Pidgeon, Helen, Williams, Angharad, Kellett, Joanne, Dunne, Michael, Curtis, Mark, O'Brien, Tracey, Lambatan, Kenneth, Rowlands, Tessa, Lloyd -Evans, Julie, Edakalathu, Jefin Jose, Hand, Campbell, Ivanova, Dima, Baker, David, Evans, Richard, Pullen, Huw, Hodkinson, Gemma, Davey, Alison, Poyser, Emma, Connor, Clare, Jordan, Caroline, Omar, Zohra, Lewis, Tracy, Ponnada, Ravi, Al-Azzani, Waheeb, Knox, Liam, Lee, Tracy, Robinson, Kathryn, Majed, Addie, Falworth, Mark, Hughes, Ben, Brooking, Deirdre, Patel, Amit, Santiago, Rodney, Smith, Christopher, Hall, Jane, Griffin, Emily, Thomas, William, Rose, David, Edkins, Janet, Gooding, Ben, Nightingale, Jess, Papanna, Madhavan, Briggs, Tom, Neal, Amy, Chadwick, Robert, Davies, Loretta, Taylor, Rod, Abel, Geoffrey, Wallace, Angus

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Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate von Slater, Martin J, Amphlett, Elizabeth M, Andrews, David M, Bravi, Gianpaolo, Burton, George, Cheasty, Anne G, Corfield, John A, Ellis, Malcolm R, Fenwick, Rebecca H, Fernandes, Stephanie, Guidetti, Rossella, Haigh, David, Hartley, C. David, Howes, Peter D, Jackson, Deborah L, Jarvest, Richard L, Lovegrove, Victoria L. H, Medhurst, Katrina J, Parry, Nigel R, Price, Helen, Shah, Pritom, Singh, Onkar M. P, Stocker, Richard, Thommes, Pia, Wilkinson, Claire, Wonacott, Alan

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Single-dose BNT162b2 vaccine protects against asymptomatic SARS-CoV-2 infection von Jones, Nick K., Rivett, Lucy, Seaman, Shaun, Samworth, Richard J., Warne, Ben, Workman, Chris, Ferris, Mark, Wright, Jo, Quinnell, Natalie, Shaw, Ashley, Goodfellow, Ian G., Lehner, Paul J., Howes, Rob, Wright, Giles, Matheson, Nicholas J., Weekes, Michael P.

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Metabolic syndrome and its effect on the outcomes of rheumatoid arthritis in a multi-ethnic cohort in Singapore von Hee, Jia Yi, Protani, Melinda M., Koh, Ee Tzun, Leong, Khai Pang

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Effect of priming interval on reactogenicity, peak immunological response, and waning after homologous and heterologous COVID-19 vaccine schedules: exploratory analyses of Com-COV,... von Shaw, Robert H, Liu, Xinxue, Stuart, Arabella S V, Greenland, Melanie, Aley, Parvinder K, Andrews, Nick J, Cameron, J Claire, Charlton, Sue, Clutterbuck, Elizabeth A, Collins, Andrea M, Dejnirattisai, Wanwisa, Dinesh, Tanya, Faust, Saul N, Ferreira, Daniela M, Finn, Adam, Green, Christopher A, Hallis, Bassam, Heath, Paul T, Hill, Helen, Lambe, Teresa, Lazarus, Rajeka, Libri, Vincenzo, Long, Fei, Mujadidi, Yama F, Plested, Emma L, Morey, Ella R, Provstgaard-Morys, Samuel, Ramasamy, Maheshi N, Ramsay, Mary, Read, Robert C, Robinson, Hannah, Screaton, Gavin R, Singh, Nisha, Turner, David P J, Turner, Paul J, Vichos, Iason, Walker, Laura L, White, Rachel, Nguyen-Van-Tam, Jonathan S, Snape, Matthew D, Munro, Alasdair P.S., Bartholomew, Jazz, Presland, Laura, Horswill, Sarah, Warren, Sarah, Varkonyi-Clifford, Sophie, Saich, Stephen, Adams, Kirsty, Ricamara, Marivic, Turner, Nicola, Yee Ting, Nicole Y., Whittley, Sarah, Rampling, Tommy, Desai, Amisha, Brown, Claire H., Qureshi, Ehsaan, Gokani, Karishma, Naker, Kush, Kellett Wright, Johanna K., Williams, Rachel L., Riaz, Tawassal, Penciu, Florentina D., Carson, Amy, Di Maso, Claudio, Mead, Gracie, Howe, Elizabeth G., Vichos, Iason, Ghulam Farooq, Mujtaba, Noristani, Rabiullah, Yao, Xin L., Oldfield, Neil J., Hammersley, Daniel, Belton, Sue, Royal, Simon, San Francisco Ramos, Alberto, Hultin, Cecilia, Galiza, Eva P., Crook, Rebecca, Bula, Marcin, Fyles, Fred, Burhan, Hassan, Maelin, Flora, Hughes, Elen, Okenyi, Emmanuel

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