Effectiveness of COVID-19 mRNA Vaccination in Preventing COVID-19-Associated Hospitalization Among Adults with Previous SARS-CoV-2 Infection - United States, June 2021-February 202... von Plumb, Ian D, Feldstein, Leora R, Barkley, Eric, Posner, Alexander B, Bregman, Howard S, Hagen, Melissa Briggs, Gerhart, Jacqueline L

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Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators von Huang, Xin, Shaffer, Paul L, Ayube, Shawn, Bregman, Howard, Chen, Hao, Lehto, Sonya G, Luther, Jason A, Matson, David J, McDonough, Stefan I, Michelsen, Klaus, Plant, Matthew H, Schneider, Stephen, Simard, Jeffrey R, Teffera, Yohannes, Yi, Shuyan, Zhang, Maosheng, DiMauro, Erin F, Gingras, Jacinthe

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Ruthenium Half-Sandwich Complexes Bound to Protein Kinase Pim-1 von Debreczeni, Judit É., Bullock, Alex N., Atilla, G. Ekin, Williams, Douglas S., Bregman, Howard, Knapp, Stefan, Meggers, Eric

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Discovery of Novel, Induced-Pocket Binding Oxazolidinones as Potent, Selective, and Orally Bioavailable Tankyrase Inhibitors von Bregman, Howard, Chakka, Nagasree, Guzman-Perez, Angel, Gunaydin, Hakan, Gu, Yan, Huang, Xin, Berry, Virginia, Liu, Jingzhou, Teffera, Yohannes, Huang, Liyue, Egge, Bryan, Mullady, Erin L, Schneider, Steve, Andrews, Paul S, Mishra, Ankita, Newcomb, John, Serafino, Randy, Strathdee, Craig A, Turci, Susan M, Wilson, Cindy, DiMauro, Erin F

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Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors von DiMauro, Erin F, Altmann, Stephen, Berry, Loren M, Bregman, Howard, Chakka, Nagasree, Chu-Moyer, Margaret, Bojic, Elma Feric, Foti, Robert S, Fremeau, Robert, Gao, Hua, Gunaydin, Hakan, Guzman-Perez, Angel, Hall, Brian E, Huang, Hongbing, Jarosh, Michael, Kornecook, Thomas, Lee, Josie, Ligutti, Joseph, Liu, Dong, Moyer, Bryan D, Ortuno, Daniel, Rose, Paul E, Schenkel, Laurie B, Taborn, Kristin, Wang, Jean, Wang, Yan, Yu, Violeta, Weiss, Matthew M

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An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells von SMALLEY, Keiran S. M, CONTRACTOR, Rooha, HERLYN, Meenhard, HAASS, Nikolas K, KULP, Angela N, EKIN ATILLA-GOKCUMEN, G, WILLIAMS, Douglas S, BREGMAN, Howard, FLAHERTY, Keith T, SOENGAS, Maria S, MEGGERS, Eric

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A Modular Synthesis of the Lamellarins:  Total Synthesis of Lamellarin G Trimethyl Ether von Handy, Scott T, Zhang, Yanan, Bregman, Howard

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Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor von Bullock, Alex N, Russo, Santina, Amos, Ann, Pagano, Nicholas, Bregman, Howard, Debreczeni, Judit E, Lee, Wen Hwa, von Delft, Frank, Meggers, Eric, Knapp, Stefan

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Inhibition of Inactive States of Tetrodotoxin-Sensitive Sodium Channels Reduces Spontaneous Firing of C-Fiber Nociceptors and Produces Analgesia in Formalin and Complete Freund's A... von Matson, David J, Hamamoto, Darryl T, Bregman, Howard, Cooke, Melanie, DiMauro, Erin F, Huang, Liyue, Johnson, Danielle, Li, Xingwen, McDermott, Jeff, Morgan, Carrie, Wilenkin, Ben, Malmberg, Annika B, McDonough, Stefan I, Simone, Donald A

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Ruthenium half-sandwich complexes as protein kinase inhibitors: derivatization of the pyridocarbazole pharmacophore ligand von Pagano, Nicholas, Maksimoska, Jasna, Bregman, Howard, Williams, Douglas S, Webster, Richard D, Xue, Feng, Meggers, Eric

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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement von Marx, Isaac E, Dineen, Thomas A, Able, Jessica, Bode, Christiane, Bregman, Howard, Chu-Moyer, Margaret, DiMauro, Erin F, Du, Bingfan, Foti, Robert S, Fremeau, Robert T, Gao, Hua, Gunaydin, Hakan, Hall, Brian E, Huang, Liyue, Kornecook, Thomas, Kreiman, Charles R, La, Daniel S, Ligutti, Joseph, Lin, Min-Hwa Jasmine, Liu, Dong, McDermott, Jeff S, Moyer, Bryan D, Peterson, Emily A, Roberts, Jonathan T, Rose, Paul, Wang, Jean, Youngblood, Beth D, Yu, Violeta, Weiss, Matthew M

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Structure-Based Design of 2‑Aminopyridine Oxazolidinones as Potent and Selective Tankyrase Inhibitors von Huang, Hongbing, Guzman-Perez, Angel, Acquaviva, Lisa, Berry, Virginia, Bregman, Howard, Dovey, Jennifer, Gunaydin, Hakan, Huang, Xin, Huang, Liyue, Saffran, Doug, Serafino, Randy, Schneider, Steve, Wilson, Cindy, DiMauro, Erin F

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Ruthenium Half-Sandwich Complexes as Protein Kinase Inhibitors:  An N-Succinimidyl Ester for Rapid Derivatizations of the Cyclopentadienyl Moiety von Bregman, Howard, Meggers, Eric

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Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis von Bambouskova, Monika, Gorvel, Laurent, Lampropoulou, Vicky, Sergushichev, Alexey, Loginicheva, Ekaterina, Johnson, Kendall, Korenfeld, Daniel, Mathyer, Mary Elizabeth, Kim, Hyeryun, Huang, Li-Hao, Duncan, Dustin, Bregman, Howard, Keskin, Abdurrahman, Santeford, Andrea, Apte, Rajendra S., Sehgal, Raghav, Johnson, Britney, Amarasinghe, Gaya K., Soares, Miguel P., Satoh, Takashi, Akira, Shizuo, Hai, Tsonwin, de Guzman Strong, Cristina, Auclair, Karine, Roddy, Thomas P., Biller, Scott A., Jovanovic, Marko, Klechevsky, Eynav, Stewart, Kelly M., Randolph, Gwendalyn J., Artyomov, Maxim N.

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Rapid Access to Unexplored Chemical Space by Ligand Scanning around a Ruthenium Center:  Discovery of Potent and Selective Protein Kinase Inhibitors von Bregman, Howard, Carroll, Patrick J, Meggers, Eric

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Discovery of a Class of Novel Tankyrase Inhibitors that Bind to Both the Nicotinamide Pocket and the Induced Pocket von Bregman, Howard, Gunaydin, Hakan, Gu, Yan, Schneider, Steve, Wilson, Cindy, DiMauro, Erin F, Huang, Xin

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The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF Kinase von Xie, Peng, Streu, Craig, Qin, Jie, Bregman, Howard, Pagano, Nicholas, Meggers, Eric, Marmorstein, Ronen

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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities von Weiss, Matthew M, Dineen, Thomas A, Marx, Isaac E, Altmann, Steven, Boezio, Alessandro, Bregman, Howard, Chu-Moyer, Margaret, DiMauro, Erin F, Feric Bojic, Elma, Foti, Robert S, Gao, Hua, Graceffa, Russell, Gunaydin, Hakan, Guzman-Perez, Angel, Huang, Hongbing, Huang, Liyue, Jarosh, Michael, Kornecook, Thomas, Kreiman, Charles R, Ligutti, Joseph, La, Daniel S, Lin, Min-Hwa Jasmine, Liu, Dong, Moyer, Bryan D, Nguyen, Hanh N, Peterson, Emily A, Rose, Paul E, Taborn, Kristin, Youngblood, Beth D, Yu, Violeta, Fremeau, Robert T

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The Discovery and Hit-to-Lead Optimization of Tricyclic Sulfonamides as Potent and Efficacious Potentiators of Glycine Receptors von Bregman, Howard, Simard, Jeffrey R, Andrews, Kristin L, Ayube, Shawn, Chen, Hao, Gunaydin, Hakan, Guzman-Perez, Angel, Hu, Jiali, Huang, Liyue, Huang, Xin, Krolikowski, Paul H, Lehto, Sonya G, Lewis, Richard T, Michelsen, Klaus, Pegman, Pamela, Plant, Matthew H, Shaffer, Paul L, Teffera, Yohannes, Yi, Shuyan, Zhang, Maosheng, Gingras, Jacinthe, DiMauro, Erin F

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Exploring Chemical Space with Organometallics: Ruthenium Complexes as Protein Kinase Inhibitors von Meggers, Eric, Atilla-Gokcumen, G. Ekin, Bregman, Howard, Maksimoska, Jasna, Mulcahy, Seann P., Pagano, Nicholas, Williams, Douglas S.

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