Sorafenib Induces Pyroptosis in Macrophages and Triggers Natural Killer Cell–Mediated Cytotoxicity Against Hepatocellular Carcinoma von Hage, Carina, Hoves, Sabine, Strauss, Léanne, Bissinger, Stefan, Prinz, Ylva, Pöschinger, Thomas, Kiessling, Fabian, Ries, Carola H.

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Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity von Hoves, Sabine, Ooi, Chia-Huey, Wolter, Carsten, Sade, Hadassah, Bissinger, Stefan, Schmittnaegel, Martina, Ast, Oliver, Giusti, Anna M, Wartha, Katharina, Runza, Valeria, Xu, Wei, Kienast, Yvonne, Cannarile, Michael A, Levitsky, Hyam, Romagnoli, Solange, De Palma, Michele, Rüttinger, Dominik, Ries, Carola H

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Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy von Kashyap, Abhishek S., Schmittnaegel, Martina, Rigamonti, Nicolò, Pais-Ferreira, Daniela, Mueller, Philipp, Buchi, Melanie, Ooi, Chia-Huey, Kreuzaler, Matthias, Hirschmann, Petra, Guichard, Alan, Rieder, Natascha, Bill, Ruben, Herting, Frank, Kienast, Yvonne, Dirnhofer, Stefan, Klein, Christian, Hoves, Sabine, Ries, Carola H., Corse, Emily, De Palma, Michele, Zippelius, Alfred

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Tumor-derived lactic acid modulates dendritic cell activation and antigen expression von Gottfried, Eva, Kunz-Schughart, Leoni A., Ebner, Stephanie, Mueller-Klieser, Wolfgang, Hoves, Sabine, Andreesen, Reinhard, Mackensen, Andreas, Kreutz, Marina

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The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models von Maser, Ilona-Petra, Hoves, Sabine, Bayer, Christa, Heidkamp, Gordon, Nimmerjahn, Falk, Eckmann, Jan, Ries, Carola H

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Quantitative profiling of tryptophan metabolites in serum, urine, and cell culture supernatants by liquid chromatography–tandem mass spectrometry von Zhu, Wentao, Stevens, Axel P., Dettmer, Katja, Gottfried, Eva, Hoves, Sabine, Kreutz, Marina, Holler, Ernst, Canelas, André B., Kema, Ido, Oefner, Peter J.

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Characterizing responsive and refractory orthotopic mouse models of hepatocellular carcinoma in cancer immunotherapy von Hage, Carina, Hoves, Sabine, Ashoff, Mailin, Schandl, Veronika, Hört, Stefan, Rieder, Natascha, Heichinger, Christian, Berrera, Marco, Ries, Carola H, Kiessling, Fabian, Pöschinger, Thomas

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Human CD34 + -derived plasmacytoid dendritic cells as surrogates for primary pDCs and potential cancer immunotherapy von Fiore, Giovanna, Weckwarth, Wolfgang, Paetzold, Kerstin, Albertí Servera, Llucia, Gies, Manuela, Rosenhauer, Jakob, Antoniolli, Martina, Nassiri, Sina, Schmeing, Stephan, Dettling, Steffen, Soni, Bhavesh, Majety, Meher, Krug, Anne B, Hoves, Sabine, Wolf, Monika Julia

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The battlefield of perforin/granzyme cell death pathways von Hoves, Sabine, Trapani, Joseph A., Voskoboinik, Ilia

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Phase Ib study of anti-CSF-1R antibody emactuzumab in combination with CD40 agonist selicrelumab in advanced solid tumor patients von Machiels, Jean-Pascal, Gomez-Roca, Carlos, Michot, Jean-Marie, Zamarin, Dmitriy, Mitchell, Tara, Catala, Gaetan, Eberst, Lauriane, Jacob, Wolfgang, Jegg, Anna-Maria, Cannarile, Michael A, Watson, Carl, Babitzki, Galina, Korski, Konstanty, Klaman, Irina, Teixeira, Priscila, Hoves, Sabine, Ries, Carola, Meneses-Lorente, Georgina, Michielin, Francesca, Christen, Randolph, Rüttinger, Dominik, Weisser, Martin, Delord, Jean-Pierre, Cassier, Philippe

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Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity von Baer, Caroline, Squadrito, Mario Leonardo, Laoui, Damya, Thompson, Danielle, Hansen, Sarah K., Kiialainen, Anna, Hoves, Sabine, Ries, Carola H., Ooi, Chia-Huey, De Palma, Michele

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CSF-1/CSF-1R targeting agents in clinical development for cancer therapy von Ries, Carola H, Hoves, Sabine, Cannarile, Michael A, Rüttinger, Dominik

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A novel role for granzymes in anti-tumor immunity von Hoves, Sabine, Sutton, Vivien R., Trapani, Joseph A.

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A drug development perspective on targeting tumor‐associated myeloid cells von Majety, Meher, Runza, Valeria, Lehmann, Christian, Hoves, Sabine, Ries, Carola H.

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Inhibitory effect of tumor cell–derived lactic acid on human T cells von Fischer, Karin, Hoffmann, Petra, Voelkl, Simon, Meidenbauer, Norbert, Ammer, Julia, Edinger, Matthias, Gottfried, Eva, Schwarz, Sabine, Rothe, Gregor, Hoves, Sabine, Renner, Kathrin, Timischl, Birgit, Mackensen, Andreas, Kunz-Schughart, Leoni, Andreesen, Reinhard, Krause, Stefan W., Kreutz, Marina

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Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy von Ries, Carola H., Cannarile, Michael A., Hoves, Sabine, Benz, Jörg, Wartha, Katharina, Runza, Valeria, Rey-Giraud, Flora, Pradel, Leon P., Feuerhake, Friedrich, Klaman, Irina, Jones, Tobin, Jucknischke, Ute, Scheiblich, Stefan, Kaluza, Klaus, Gorr, Ingo H., Walz, Antje, Abiraj, Keelara, Cassier, Philippe A., Sica, Antonio, Gomez-Roca, Carlos, de Visser, Karin E., Italiano, Antoine, Le Tourneau, Christophe, Delord, Jean-Pierre, Levitsky, Hyam, Blay, Jean-Yves, Rüttinger, Dominik

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Chemotherapy Combines Effectively with Anti-PD-L1 Treatment and Can Augment Antitumor Responses von Cubas, Rafael, Moskalenko, Marina, Cheung, Jeanne, Yang, Michelle, McNamara, Erin, Xiong, Huizhong, Hoves, Sabine, Ries, Carola H, Kim, Jeong, Gould, Stephen

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T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells von Marigo, Ilaria, Zilio, Serena, Desantis, Giacomo, Mlecnik, Bernhard, Agnellini, Andrielly H.R., Ugel, Stefano, Sasso, Maria Stella, Qualls, Joseph E., Kratochvill, Franz, Zanovello, Paola, Molon, Barbara, Ries, Carola H., Runza, Valeria, Hoves, Sabine, Bilocq, Amélie M., Bindea, Gabriela, Mazza, Emilia M.C., Bicciato, Silvio, Galon, Jérôme, Murray, Peter J., Bronte, Vincenzo

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Therapeutic Efficacy of Bifunctional siRNA Combining TGF-β1 Silencing with RIG-I Activation in Pancreatic Cancer von ELLERMEIER, Jonathan, JIWU WEI, HARTMANN, Gunther, ENDRES, Stefan, SCHNURR, Max, DUEWELL, Peter, HOVES, Sabine, STIEG, Mareike R, ADUNKA, Tina, NOERENBERG, Daniel, ANDERS, Hans-Joachim, MAYR, Doris, POECK, Hendrik

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Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages von Murgaski, Aleksandar, Kiss, Máté, Van Damme, Helena, Kancheva, Daliya, Vanmeerbeek, Isaure, Keirsse, Jiri, Hadadi, Eva, Brughmans, Jan, Arnouk, Sana M, Hamouda, Ahmed E I, Debraekeleer, Ayla, Bosteels, Victor, Elkrim, Yvon, Boon, Louis, Hoves, Sabine, Vandamme, Niels, Deschoemaeker, Sofie, Janssens, Sophie, Garg, Abhishek D, Vande Velde, Greetje, Schmittnaegel, Martina, Ries, Carola H, Laoui, Damya

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