A Population Pharmacokinetic Meta-analysis of Sunitinib Malate (SU11248) and Its Primary Metabolite (SU12662) in Healthy Volunteers and Oncology Patients von HOUK, Brett E, BELLO, Carlo L, KANG, Dongwoo, AMANTEA, Michael

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Impact of Sotorasib on the Pharmacokinetics and Pharmacodynamics of Metformin, a MATE1/2K Substrate, in Healthy Subjects von Vuu, Irene, Wahlstrom, Jan, Houk, Brett E.

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The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity von Canon, Jude, Rex, Karen, Saiki, Anne Y., Mohr, Christopher, Cooke, Keegan, Bagal, Dhanashri, Gaida, Kevin, Holt, Tyler, Knutson, Charles G., Koppada, Neelima, Lanman, Brian A., Werner, Jonathan, Rapaport, Aaron S., San Miguel, Tisha, Ortiz, Roberto, Osgood, Tao, Sun, Ji-Rong, Zhu, Xiaochun, McCarter, John D., Volak, Laurie P., Houk, Brett E., Fakih, Marwan G., O’Neil, Bert H., Price, Timothy J., Falchook, Gerald S., Desai, Jayesh, Kuo, James, Govindan, Ramaswamy, Hong, David S., Ouyang, Wenjun, Henary, Haby, Arvedson, Tara, Cee, Victor J., Lipford, J. Russell

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Pharmacokinetics of Tarlatamab, a Delta-Like Ligand-3 (DLL3) Targeted Half-Life Extended Bispecific T-Cell Engager (BiTE ® ) Immunotherapy in Adult Patients with Previously Treated... von Minocha, Mukul, Thompson, Corbin G, Murphy, Alexis, Zhou, Yanchen, Brandl, Christian, Parkes, Amanda, Chen, Xi, Yu, Brian, Martinez, Pablo, Houk, Brett E

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Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis von Houk, Brett E, Bello, Carlo L, Poland, Bill, Rosen, Lee S, Demetri, George D, Motzer, Robert J

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Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Properties of Rozibafusp Alfa, a Bispecific Inhibitor of BAFF and ICOSL: Analyses of Phase I Clinical Trials von Abuqayyas, Lubna, Chen, Po‐Wei, Santos, Marcia Teixeira, Parnes, Jane R., Doshi, Sameer, Dutta, Sandeep, Houk, Brett E.

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First-in-Human Study of PF-05212384 (PKI-587), a Small-Molecule, Intravenous, Dual Inhibitor of PI3K and mTOR in Patients with Advanced Cancer von Shapiro, Geoffrey I, Bell-McGuinn, Katherine M, Molina, Julian R, Bendell, Johanna, Spicer, James, Kwak, Eunice L, Pandya, Susan S, Millham, Robert, Borzillo, Gary, Pierce, Kristen J, Han, Lixin, Houk, Brett E, Gallo, Jorge D, Alsina, Maria, Braña, Irene, Tabernero, Josep

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A Phase I Study of PF-04929113 (SNX-5422), an Orally Bioavailable Heat Shock Protein 90 Inhibitor, in Patients with Refractory Solid Tumor Malignancies and Lymphomas von RAJAN, Arun, KELLY, Ronan J, MANNARGUDI, Baskar, FIGG, William D, HOUK, Brett E, SHNAIDMAN, Michael, BREGA, Nicoletta, GIACCONE, Giuseppe, TREPEL, Jane B, YEONG SANG KIM, ALARCON, Sylvia V, KUMMAR, Shivaani, GUTIERREZ, Martin, CRANDON, Sonja, ZEIN, Wadih M, JAIN, Lokesh

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Phase I study of PF-04691502, a small-molecule, oral, dual inhibitor of PI3K and mTOR, in patients with advanced cancer von Britten, Carolyn D., Adjei, Alex A., Millham, Robert, Houk, Brett E., Borzillo, Gary, Pierce, Kristen, Wainberg, Zev A., LoRusso, Patricia M.

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Standard Error of Empirical Bayes Estimate in NONMEM® VI von Kang, Dongwoo, Bae, Kyun-Seop, Houk, Brett E., Savic, Radojka M., Karlsson, Mats O.

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Modeling and simulations relating overall survival to tumor growth inhibition in renal cell carcinoma patients von Claret, Laurent, Mercier, Francois, Houk, Brett E., Milligan, Peter A., Bruno, Rene

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Determination of PF-04928473 in human plasma using liquid chromatography with tandem mass spectrometry von Jain, Lokesh, Gardner, Erin R., Venitz, Jürgen, Giaccone, Giuseppe, Houk, Brett E., Figg, William D.

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KRAS G12C Inhibition with Sotorasib in Advanced Solid Tumors von Hong, David S, Fakih, Marwan G, Strickler, John H, Desai, Jayesh, Durm, Gregory A, Shapiro, Geoffrey I, Falchook, Gerald S, Price, Timothy J, Sacher, Adrian, Denlinger, Crystal S, Bang, Yung-Jue, Dy, Grace K, Krauss, John C, Kuboki, Yasutoshi, Kuo, James C, Coveler, Andrew L, Park, Keunchil, Kim, Tae Won, Barlesi, Fabrice, Munster, Pamela N, Ramalingam, Suresh S, Burns, Timothy F, Meric-Bernstam, Funda, Henary, Haby, Ngang, Jude, Ngarmchamnanrith, Gataree, Kim, June, Houk, Brett E, Canon, Jude, Lipford, J Russell, Friberg, Gregory, Lito, Piro, Govindan, Ramaswamy, Li, Bob T

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Effect of axitinib on the QT interval in healthy volunteers von Ruiz-Garcia, Ana, Houk, Brett E., Pithavala, Yazdi K., Toh, Melvin, Sarapa, Nenad, Tortorici, Michael A.

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Phase I Trial of the HSP90 Inhibitor PF-04929113 (SNX5422) in Adult Patients With Recurrent, Refractory Hematologic Malignancies von Reddy, Nishitha, Voorhees, Peter M, Houk, Brett E, Brega, Nicoletta, Hinson, James M, Jillela, Anand

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Distribution, Metabolism, and Excretion of Gedatolisib in Healthy Male Volunteers After a Single Intravenous Infusion von Houk, Brett E., Alvey, Christine W., Visswanathan, Ravi, Kirkovsky, Leonid, Matschke, Kyle T., Kimoto, Emi, Ryder, Tim, Obach, R. Scott, Durairaj, Chandrasekar

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Erratum to: Phase I study of PF-04691502, a small-molecule, oral, dual inhibitor of PI3K and mTOR, in patients with advanced cancer von Britten, Carolyn D., Adjei, Alex A., Millham, Robert, Houk, Brett E., Borzillo, Gary, Pierce, Kristen, Wainberg, Zev A., LoRusso, Patricia M.

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Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors von Buchanan, John L., Newcomb, John R., Carney, David P., Chaffee, Stuart C., Chai, Lilly, Cupples, Rod, Epstein, Linda F., Gallant, Paul, Gu, Yan, Harmange, Jean-Christophe, Hodge, Kathy, Houk, Brett E., Huang, Xin, Jona, Janan, Joseph, Smriti, Jun, H. Toni, Kumar, Rakesh, Li, Chun, Lu, John, Menges, Tom, Morrison, Michael J., Novak, Perry M., van der Plas, Simon, Radinsky, Robert, Rose, Paul E., Sawant, Satin, Sun, Ji-Rong, Surapaneni, Sekhar, Turci, Susan M., Xu, Keyang, Yanez, Evelyn, Zhao, Huilin, Zhu, Xiaotian

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Pharmacokinetics of Tarlatamab, a Delta-Like Ligand-3 (DLL3) Targeted Half-Life Extended Bispecific T-Cell Engager (BiTE®) Immunotherapy in Adult Patients with Previously Treated S... von Minocha, Mukul, Thompson, Corbin G., Murphy, Alexis, Zhou, Yanchen, Brandl, Christian, Parkes, Amanda, Chen, Xi, Yu, Brian, Martinez, Pablo, Houk, Brett E.

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Kinetic modeling of plasmid DNA degradation in rat plasma von Houk, B E, Hochhaus, G, Hughes, J A

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