The effect of early, comprehensive genomic testing on clinical care in neonatal diabetes: an international cohort study von De Franco, Elisa, PhD, Flanagan, Sarah E, PhD, Houghton, Jayne AL, PhD, Allen, Hana Lango, PhD, Mackay, Deborah JG, PhD, Temple, I Karen, Prof, Ellard, Sian, Prof, Hattersley, Andrew T, Prof

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Using referral rates for genetic testing to determine the incidence of a rare disease: The minimal incidence of congenital hyperinsulinism in the UK is 1 in 28,389 von Yau, Daphne, Laver, Thomas W., Dastamani, Antonia, Senniappan, Senthil, Houghton, Jayne A. L., Shaikh, Guftar, Cheetham, Tim, Mushtaq, Talat, Kapoor, Ritika R., Randell, Tabitha, Ellard, Sian, Shah, Pratik, Banerjee, Indraneel, Flanagan, Sarah E.

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Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN‐173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrom... von AGRAWAL, A., HOUGHTON, L. A., MORRIS, J., REILLY, B., GUYONNET, D., GOUPIL FEUILLERAT, N., SCHLUMBERGER, A., JAKOB, S., WHORWELL, P. J.

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SLC2A2 mutations can cause neonatal diabetes, suggesting GLUT2 may have a role in human insulin secretion von Sansbury, F. H., Flanagan, S. E., Houghton, J. A. L., Shuixian Shen, F. L., Al-Senani, A. M. S., Habeb, A. M., Abdullah, M., Kariminejad, A., Ellard, S., Hattersley, A. T.

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Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis von Weedon, Michael N, Cebola, Inês, Patch, Ann-Marie, Flanagan, Sarah E, De Franco, Elisa, Caswell, Richard, Rodríguez-Seguí, Santiago A, Shaw-Smith, Charles, Cho, Candy H-H, Allen, Hana Lango, Houghton, Jayne A L, Roth, Christian L, Chen, Rongrong, Hussain, Khalid, Marsh, Phil, Vallier, Ludovic, Murray, Anna, Ellard, Sian, Ferrer, Jorge, Hattersley, Andrew T

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Systematic review: the efficacy of treatments for irritable bowel syndrome – a European perspective von TACK, J., FRIED, M., HOUGHTON, L. A., SPICAK, J., FISHER, G.

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Hyperinsulinemic hypoglycemia in children and adolescents: Recent advances in understanding of pathophysiology and management von Gϋemes, Maria, Rahman, Sofia Asim, Kapoor, Ritika R., Flanagan, Sarah, Houghton, Jayne A. L., Misra, Shivani, Oliver, Nick, Dattani, Mehul Tulsidas, Shah, Pratik

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Effect of a second-generation α2δ ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome von Houghton, L A, Fell, C, Whorwell, P J, Jones, I, Sudworth, D P, Gale, J D

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Noninvasive Fetal Genotyping by Droplet Digital PCR to Identify Maternally Inherited Monogenic Diabetes Variants von Caswell, Richard C, Snowsill, Tristan, Houghton, Jayne A L, Chakera, Ali J, Shepherd, Maggie H, Laver, Thomas W, Knight, Bridget A, Wright, David, Hattersley, Andrew T, Ellard, Sian

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The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers von Houghton, L A, Lea, R, Jackson, N, Whorwell, P J

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A meta‐analysis of immunogenetic Case–Control Association Studies in irritable bowel syndrome von Czogalla, B., Schmitteckert, S., Houghton, L. A., Sayuk, G. S., Camilleri, M., Olivo‐Diaz, A., Spiller, R., Wouters, M. M., Boeckxstaens, G., Lorenzo Bermejo, J., Niesler, B.

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Improved genetic testing for monogenic diabetes using targeted next-generation sequencing von Ellard, S., Lango Allen, H., De Franco, E., Flanagan, S. E., Hysenaj, G., Colclough, K., Houghton, J. A. L., Shepherd, M., Hattersley, A. T., Weedon, M. N., Caswell, R.

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Phenotyping of subjects for large scale studies on patients with IBS von Boeckxstaens, G. E., Drug, V., Dumitrascu, D., Farmer, A. D., Hammer, J., Hausken, T., Niesler, B., Pohl, D., Pojskic, L., Polster, A., Simren, M., Goebel‐Stengel, M., Van Oudenhove, L., Vassallo, M., Wensaas, K.‐A., Aziz, Q., Houghton, L. A.

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Bringing precision medicine to the management of pregnancy in women with glucokinase-MODY: a study of diagnostic accuracy and feasibility of non-invasive prenatal testing von Hughes, Alice E., Houghton, Jayne A. L., Bunce, Benjamin, Chakera, Ali J., Spyer, Gill, Shepherd, Maggie H., Flanagan, Sarah E., Hattersley, Andrew T.

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Increased platelet depleted plasma 5-hydroxytryptamine concentration following meal ingestion in symptomatic female subjects with diarrhoea predominant irritable bowel syndrome von Houghton, L A, Atkinson, W, Whitaker, R P, Whorwell, P J, Rimmer, M J

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Birth weight and diazoxide unresponsiveness strongly predict the likelihood of congenital hyperinsulinism due to a mutation in ABCC8 or KCNJ11 von Hewat, Thomas I, Yau, Daphne, Jerome, Joseph C S, Laver, Thomas W, Houghton, Jayne A L, Shields, Beverley M, Flanagan, Sarah E, Patel, Kashyap A

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Chromosome 20p11.2 deletions cause congenital hyperinsulinism via the loss of FOXA2 or its regulatory elements von Laver, Thomas W, Wakeling, Matthew N, Caswell, Richard C, Bunce, Benjamin, Yau, Daphne, Männistö, Jonna M E, Houghton, Jayne A L, Hopkins, Jasmin J, Weedon, Michael N, Saraff, Vrinda, Kershaw, Melanie, Honey, Engela M, Murphy, Nuala, Giri, Dinesh, Nath, Stuart, Tangari Saredo, Ana, Banerjee, Indraneel, Hussain, Khalid, Owens, Nick D L, Flanagan, Sarah E

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Gut‐focused hypnotherapy normalizes disordered rectal sensitivity in patients with irritable bowel syndrome von Lea, R., Houghton, L. A., Calvert, E. L., Larder, S., Gonsalkorale, W. M., Whelan, V., Randles, J., Cooper, P., Cruickshanks, P., Miller, V., Whorwell, P. J.

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Towards a better understanding of abdominal bloating and distension in functional gastrointestinal disorders von Houghton, L. A., Whorwell, P. J.

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Visceral sensation and emotion: a study using hypnosis von Houghton, L A, Calvert, E L, Jackson, N A, Cooper, P, Whorwell, P J

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