Natural Blues: Structure Meets Function in Anthocyanins von Houghton, Alan, Appelhagen, Ingo, Martin, Cathie

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Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation von Cohen, Adam D, Schaer, David A, Liu, Cailian, Li, Yanyun, Hirschhorn-Cymmerman, Daniel, Kim, Soo Chong, Diab, Adi, Rizzuto, Gabrielle, Duan, Fei, Perales, Miguel A, Merghoub, Taha, Houghton, Alan N, Wolchok, Jedd D

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Monocytic CCR2+ Myeloid-Derived Suppressor Cells Promote Immune Escape by Limiting Activated CD8 T-cell Infiltration into the Tumor Microenvironment von LESOKHIN, Alexander M, HOHL, Tobias M, MERGHOUB, Taha, WOLCHOK, Jedd D, KITANO, Shigehisa, CORTEZ, Czrina, HIRSCHHORN-CYMERMAN, Daniel, AVOGADRI, Francesca, RIZZUTO, Gabrielle A, LAZARUS, John J, PAME, Eric G, HOUGHTON, Alan N

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Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment von Budhu, Sadna, Schaer, David A, Li, Yongbiao, Toledo-Crow, Ricardo, Panageas, Katherine, Yang, Xia, Zhong, Hong, Houghton, Alan N, Silverstein, Samuel C, Merghoub, Taha, Wolchok, Jedd D

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Alphavirus replicon particles expressing TRP-2 provide potent therapeutic effect on melanoma through activation of humoral and cellular immunity von Avogadri, Francesca, Merghoub, Taha, Maughan, Maureen F, Hirschhorn-Cymerman, Daniel, Morris, John, Ritter, Erika, Olmsted, Robert, Houghton, Alan N, Wolchok, Jedd D

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Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype von Hirschhorn-Cymerman, Daniel, Budhu, Sadna, Kitano, Shigehisa, Liu, Cailian, Zhao, Feng, Zhong, Hong, Lesokhin, Alexander M, Avogadri-Connors, Francesca, Yuan, Jianda, Li, Yanyun, Houghton, Alan N, Merghoub, Taha, Wolchok, Jedd D

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Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs von Nakahara, Takeshi, Uchi, Hiroshi, Lesokhin, Alexander M., Avogadri, Francesca, Rizzuto, Gabrielle A., Hirschhorn-Cymerman, Daniel, Panageas, Katherine S., Merghoub, Taha, Wolchok, Jedd D., Houghton, Alan N.

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Final Version of the American Joint Committee on Cancer Staging System for Cutaneous Melanoma von BALCH, Charles M, BUZAID, Antonio C, MCMASTERS, Kelly M, MIHM, Martin F, MORTON, Donald L, REINTGEN, Douglas S, ROSS, Merrick I, SOBER, Arthur, THOMPSON, John A, THOMPSON, John F, SOONG, Seng-Jaw, ATKINS, Michael B, CASCINELLI, Natale, COIT, Daniel G, FLEMING, Irvin D, GERSHENWALD, Jeffrey E, HOUGHTON, Alan JR, KIRKWOOD, John M

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Two Distinct Categories of Focal Deletions in Cancer Genomes von Rajaram, Megha, Zhang, Jianping, Wang, Tim, Li, Jinyu, Kuscu, Cem, Qi, Huan, Kato, Mamoru, Grubor, Vladimir, Weil, Robert J, Helland, Aslaug, Borrenson-Dale, Anne-Lise, Cho, Kathleen R, Levine, Douglas A, Houghton, Alan N, Wolchok, Jedd D, Myeroff, Lois, Markowitz, Sanford D, Lowe, Scott W, Zhang, Michael, Krasnitz, Alex, Lucito, Robert, Mu, David, Powers, R Scott

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Focus on melanoma von Houghton, Alan N, Polsky, David

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Cutting Edge: OX40 Agonists Can Drive Regulatory T Cell Expansion if the Cytokine Milieu Is Right von Ruby, Carl E, Yates, Melissa A, Hirschhorn-Cymerman, Daniel, Chlebeck, Peter, Wolchok, Jedd D, Houghton, Alan N, Offner, Halina, Weinberg, Andrew D

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GITR pathway activation abrogates tumor immune suppression through loss of regulatory T cell lineage stability von Schaer, David A, Budhu, Sadna, Liu, Cailian, Bryson, Campbell, Malandro, Nicole, Cohen, Adam, Zhong, Hong, Yang, Xia, Houghton, Alan N, Merghoub, Taha, Wolchok, Jedd D

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Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells von Turk, Mary Jo, Guevara-Patiño, José A, Rizzuto, Gabrielle A, Engelhorn, Manuel E, Sakaguchi, Shimon, Houghton, Alan N

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OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis von Hirschhorn-Cymerman, Daniel, Rizzuto, Gabrielle A, Merghoub, Taha, Cohen, Adam D, Avogadri, Francesca, Lesokhin, Alexander M, Weinberg, Andrew D, Wolchok, Jedd D, Houghton, Alan N

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An Evidence-based Staging System for Cutaneous Melanoma von Balch, Charles M, Soong, Seng-Jaw, Atkins, Michael B, Buzaid, Antonio C, Cascinelli, Natale, Coit, Daniel G, Fleming, Irvin D, Gershenwald, Jeffrey E, Houghton, Alan, Jr, Kirkwood, John M, McMasters, Kelly M, Mihm, Martin F, Morton, Donald L, Reintgen, Douglas S, Ross, Merrick I, Sober, Arthur, Thompson, John A, Thompson, John F

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Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain von Cao, Hua, Dai, Peihong, Wang, Weiyi, Li, Hao, Yuan, Jianda, Wang, Fangjin, Fang, Chee-Mun, Pitha, Paula M, Liu, Jia, Condit, Richard C, McFadden, Grant, Merghoub, Taha, Houghton, Alan N, Young, James W, Shuman, Stewart, Deng, Liang

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Profile of immune cells in axillary lymph nodes predicts disease-free survival in breast cancer von Kohrt, Holbrook E, Nouri, Navid, Nowels, Kent, Johnson, Denise, Holmes, Susan, Lee, Peter P

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Glucocorticoid-Induced TNF Receptor Family Related Gene Activation Overcomes Tolerance/Ignorance to Melanoma Differentiation Antigens and Enhances Antitumor Immunity von Ramirez-Montagut, Teresa, Chow, Andrew, Hirschhorn-Cymerman, Daniel, Terwey, Theis H, Kochman, Adam A, Lu, Sydney, Miles, Randy C, Sakaguchi, Shimon, Houghton, Alan N, van den Brink, Marcel R. M

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Immune recognition of self in immunity against cancer von Houghton, Alan N, Guevara-Patiño, José A

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Peptide-Loaded Langerhans Cells, Despite Increased IL15 Secretion and T-Cell Activation In Vitro, Elicit Antitumor T-Cell Responses Comparable to Peptide-Loaded Monocyte-Derived De... von ROMANO, Emanuela, ROSSI, Marco, JIANDA YUAN, YOUNG, James W, RATZINGER, Gudrun, DE COS, Maria-Angeles, CHUNG, David J, PANAGEAS, Katherine S, WOLCHOCK, Jedd D, HOUGHTON, Alan N, CHAPMAN, Paul B, HELLER, Glenn

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