The value of antimicrobial peptides in the age of resistance von Magana, Maria, Pushpanathan, Muthuirulan, Santos, Ana L, Leanse, Leon, Fernandez, Michael, Ioannidis, Anastasios, Giulianotti, Marc A, Apidianakis, Yiorgos, Bradfute, Steven, Ferguson, Andrew L, Cherkasov, Artem, Seleem, Mohamed N, Pinilla, Clemencia, de la Fuente-Nunez, Cesar, Lazaridis, Themis, Dai, Tianhong, Houghten, Richard A, Hancock, Robert E W, Tegos, George P

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Shifting from the single to the multitarget paradigm in drug discovery von Medina-Franco, José L., Giulianotti, Marc A., Welmaker, Gregory S., Houghten, Richard A.

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Mu-Opioid receptor biased ligands: A safer and painless discovery of analgesics? von Madariaga-Mazón, Abraham, Marmolejo-Valencia, Andrés F., Li, Yangmei, Toll, Lawrence, Houghten, Richard A., Martinez-Mayorga, Karina

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Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide von Li, Yangmei, Eans, Shainnel O, Ganno-Sherwood, Michelle, Eliasof, Abbe, Houghten, Richard A, McLaughlin, Jay P

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Chemoinformatic Analysis of Combinatorial Libraries, Drugs, Natural Products, and Molecular Libraries Small Molecule Repository von Singh, Narender, Guha, Rajarshi, Giulianotti, Marc A, Pinilla, Clemencia, Houghten, Richard A, Medina-Franco, Jose L

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The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (M... von Ericson, Mark D, Freeman, Katie T, LaVoi, Travis M, Donow, Haley M, Santos, Radleigh G, Giulianotti, Marc A, Pinilla, Clemencia, Houghten, Richard A, Haskell-Luevano, Carrie

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Expanding the medicinally relevant chemical space with compound libraries von López-Vallejo, Fabian, Giulianotti, Marc A., Houghten, Richard A., Medina-Franco, José L.

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Discovery of Novel Inhibitors of a Disintegrin and Metalloprotease 17 (ADAM17) Using Glycosylated and Non-glycosylated Substrates von Minond, Dmitriy, Cudic, Mare, Bionda, Nina, Giulianotti, Marc, Maida, Laura, Houghten, Richard A., Fields, Gregg B.

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Combinatorial Libraries As a Tool for the Discovery of Novel, Broad-Spectrum Antibacterial Agents Targeting the ESKAPE Pathogens von Fleeman, Renee, LaVoi, Travis M, Santos, Radleigh G, Morales, Angela, Nefzi, Adel, Welmaker, Gregory S, Medina-Franco, José L, Giulianotti, Marc A, Houghten, Richard A, Shaw, Lindsey N

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Identification of a Novel Polyamine Scaffold With Potent Efflux Pump Inhibition Activity Toward Multi-Drug Resistant Bacterial Pathogens von Fleeman, Renee M, Debevec, Ginamarie, Antonen, Kirsten, Adams, Jessie L, Santos, Radleigh G, Welmaker, Gregory S, Houghten, Richard A, Giulianotti, Marc A, Shaw, Lindsey N

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Correction to “Discovery of Nanomolar Melanocortin‑3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High Throughput ‘Unbiased’ Sc... von Doering, Skye R., Freeman, Katie, Debevec, Ginamarie, Geer, Phaedra, Santos, Radleigh G., Lavoi, Travis M., Giulianotti, Marc A., Pinilla, Clemencia, Appel, Jon R., Houghten, Richard A., Ericson, Mark D., Haskell-Luevano, Carrie

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Identification of 5,6-dihydroimidazo[2,1-b]thiazoles as a new class of antimicrobial agents von Li, Yangmei, Bionda, Nina, Fleeman, Renee, Wang, Hongjie, Ozawa, Akihiko, Houghten, Richard A., Shaw, Lindsey

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Activity of ADAM17 (a Disintegrin and Metalloprotease 17) Is Regulated by Its Noncatalytic Domains and Secondary Structure of its Substrates von Stawikowska, Roma, Cudic, Mare, Giulianotti, Marc, Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy

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Potent μ‑Opioid Receptor Agonists from Cyclic Peptides Tyr‑c[d‑Lys-Xxx-Tyr-Gly]: Synthesis, Biological, and Structural Evaluation von Li, Yangmei, Cazares, Margret, Wu, Jinhua, Houghten, Richard A, Toll, Laurence, Dooley, Colette

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Novel Cyclic Lipopeptides Fusaricidin Analogs for Treating Wound Infections von Gil, Joel, Pastar, Irena, Houghten, Richard A., Padhee, Shruti, Higa, Alexander, Solis, Michael, Valdez, Jose, Head, Cheyanne R., Michaels, Heather, Lenhart, Brian, Simms, Colin, Williams, Brandon, Cudic, Predrag, Davis, Stephen C.

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A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery von Palrasu, Manikandan, Knapinska, Anna M, Diez, Juan, Smith, Lyndsay, LaVoi, Travis, Giulianotti, Marc, Houghten, Richard A, Fields, Gregg B, Minond, Dmitriy

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Palladium-Catalyzed C–H Functionalization Using Guanidine as a Directing Group: Ortho Arylation and Olefination of Arylguanidines von Shao, Jiaan, Chen, Wenteng, Giulianotti, Marc A, Houghten, Richard A, Yu, Yongping

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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity von Schimmer, Aaron D., Welsh, Kate, Pinilla, Clemencia, Wang, Zhiliang, Krajewska, Maryla, Bonneau, Marie-Josee, Pedersen, Irene M., Kitada, Shinichi, Scott, Fiona L., Bailly-Maitre, Beatrice, Glinsky, Gennadi, Scudiero, Dominick, Sausville, Edward, Salvesen, Guy, Nefzi, Adel, Ostresh, John M., Houghten, Richard A., Reed, John C.

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Discovery of Nanomolar Melanocortin‑3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput “Unbiased” Screening Campaig... von Doering, Skye R, Freeman, Katie, Debevec, Ginamarie, Geer, Phaedra, Santos, Radleigh G, Lavoi, Travis M, Giulianotti, Marc A, Pinilla, Clemencia, Appel, Jon R, Houghten, Richard A, Ericson, Mark D, Haskell-Luevano, Carrie

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Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin‑4 Receptor and Equipotent wi... von Ericson, Mark D, Doering, Skye R, Larson, Courtney M, Freeman, Katie T, LaVoi, Travis M, Donow, Haley M, Santos, Radleigh G, Cho, Rachel H, Koerperich, Zoe M, Giulianotti, Marc A, Pinilla, Clemencia, Houghten, Richard A, Haskell-Luevano, Carrie

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