The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study von James, Paula D., Notley, Colleen, Hegadorn, Carol, Leggo, Jayne, Tuttle, Angie, Tinlin, Shawn, Brown, Christine, Andrews, Chandler, Labelle, Andrea, Chirinian, Yvette, O'Brien, Lee, Othman, Maha, Rivard, Georges, Rapson, Dilys, Hough, Christine, Lillicrap, David

Volltext

N-linked glycosylation modulates the immunogenicity of recombinant human factor VIII in hemophilia A mice von Lai, Jesse D, Swystun, Laura L, Cartier, Dominique, Nesbitt, Kate, Zhang, Cunjie, Hough, Christine, Dennis, James W, Lillicrap, David

Volltext

Dexamethasone promotes durable factor VIII-specific tolerance in hemophilia A mice via thymic mechanisms von Georgescu, Maria T, Moorehead, Paul C, van Velzen, Alice S, Nesbitt, Kate, Reipert, Birgit M, Steinitz, Katharina N, Schuster, Maria, Hough, Christine, Lillicrap, David

Volltext

Omental implantation of BOECs in hemophilia dogs results in circulating FVIII antigen and a complex immune response von Ozelo, Margareth C., Vidal, Barbara, Brown, Christine, Notley, Colleen, Hegadorn, Carol, Webster, Sandra, Harpell, Lori, Ahlin, James, Winterborn, Andrew, Handforth, Janine, Arruda, Valder R., Hough, Christine, Lillicrap, David

Volltext

Recombinant Factor VIII Fc Inhibits B Cell Activation via Engagement of the FcγRIIB Receptor von Georgescu, Maria T, Moorehead, Paul C, Liu, Tongyao, Dumont, Jennifer, Scott, David W, Hough, Christine, Lillicrap, David

Volltext

Anti-CD3 prevents factor VIII inhibitor development in hemophilia A mice by a regulatory CD4+CD25+-dependent mechanism and by shifting cytokine production to favor a Th1 response von Waters, Braden, Qadura, Mohammad, Burnett, Erin, Chegeni, Rouzbeh, Labelle, Andrea, Thompson, Patrick, Hough, Christine, Lillicrap, David

Volltext

A MicroRNA-regulated and GP64-pseudotyped Lentiviral Vector Mediates Stable Expression of FVIII in a Murine Model of Hemophilia A von Matsui, Hideto, Hegadorn, Carol, Ozelo, Margareth, Burnett, Erin, Tuttle, Angie, Labelle, Andrea, McCray, Paul B, Naldini, Luigi, Brown, Brian, Hough, Christine, Lillicrap, David

Volltext

Contemporary Influences on the Role of Imams in Britain: A Critical Analysis of Leadership and Professionalisation for the Imamate in 21st Century Britain von Hough, Christine Victoria, Abbott-Halpin, Edward, Mahmood, Tariq, Giles, Jessica

Volltext

Biological considerations of plasma-derived and recombinant factor VIII immunogenicity von Lai, Jesse, Hough, Christine, Tarrant, Julie, Lillicrap, David

Volltext

Heterogeneity and reciprocity of FVIII and VWF expression, and the response to shear stress in cultured human endothelial cells von Hough, Christine, Notley, Colleen, Mo, Aomei, Videl, Barbara, Lillicrap, David

Volltext

Mice possess a more limited natural antihuman factor VIII antibody repertoire than humans that is produced disproportionately by marginal zone B cells von Cormier, Matthew, Burnett, Erin, Mo, Aomei, Notley, Colleen, Tijet, Nathalie, Christie-Holmes, Natasha, Hough, Christine, Lillicrap, David

Volltext

Transgene-host cell interactions mediate significant influences on the production, stability, and function of recombinant canine FVIII von Crawford, Bredon, Ozelo, Margareth C, Ogiwara, Kenichi, Ahlin, James, Albanez, Silvia, Hegadorn, Carol, Harpell, Lori, Hough, Christine, Lillicrap, David

Volltext

Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia... von Gallo-Penn, Angela M., Shirley, Pamela S., Andrews, Julie L., Tinlin, Shawn, Webster, Sandy, Cameron, Cherie, Hough, Christine, Notley, Colleen, Lillicrap, David, Kaleko, Michael, Connelly, Sheila

Volltext

Aberrant Splicing and Premature Termination of Transcription of the FVIII Gene as a Cause of Severe Canine Hemophilia A: Similarities with the Intron 22 Inversion Mutation in Human... von Hough, Christine, Kamisue, Seiki, Cameron, Cherie, Notley, Colleen, Tinlin, Shawn, Giles, Alan, Lillicrap, David

Volltext

A Novel Von Willebrand Factor Fragment Acts As a Chaperone to Prolong the Half-Life of Recombinant Human FVIII (Simoctocog Alfa) in Hemophilia a Dogs and FVIII/VWF Double Knockout... von Solecka-Witulska, Barbara A, Lillicrap, David, Hough, Christine, Kannicht, Christoph

Volltext

Transforming Rehabilitation and its impact on a locally-based rehabilitation programme for Black and Minority Ethnic and Muslim offenders von Hough, Christine Victoria

Volltext

To clear or to fear: An innate perspective on factor VIII immunity von Lai, Jesse Derek, Georgescu, Maria Teofana, Hough, Christine, Lillicrap, David

Volltext

Cell type–specific regulation of von Willebrand factor expression by the E4BP4 transcriptional repressor von Hough, Christine, Cuthbert, Carla D., Notley, Colleen, Brown, Christine, Hegadorn, Carol, Berber, Ergul, Lillicrap, David

Volltext

The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study von James, P. D., Notley, C., Hegadorn, C., Leggo, J., Tuttle, A., Tinlin, S., Brown, C., Andrews, C., Labelle, A., Chirinian, Y., O'Brien, L., Othman, M., Rivard, G., Rapson, D., Hough, C., Lillicrap, D.

Volltext

A Factor VIII Fusion with an Inactivated FIX Generates a Biologically Active Molecule with Delayed Clearance in a FVIII/VWF Knockout Mouse Model von Akinwale, Oladipo Jude, Wilkinson, Ian, Hough, Christine, Lillicrap, David, Makris, Michael, Ross, Richard

Volltext