Human Fatty Liver Disease: Old Questions and New Insights von Cohen, Jonathan C., Horton, Jay D., Hobbs, Helen H.

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Nonalcoholic Fatty Liver Disease and Cardiovascular Risk: A Scientific Statement From the American Heart Association von Duell, P. Barton, Welty, Francine K., Miller, Michael, Chait, Alan, Hammond, Gmerice, Ahmad, Zahid, Cohen, David E., Horton, Jay D., Pressman, Gregg S., Toth, Peter P.

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A Highly Durable RNAi Therapeutic Inhibitor of PCSK9 von Fitzgerald, Kevin, White, Suellen, Borodovsky, Anna, Bettencourt, Brian R, Strahs, Andrew, Clausen, Valerie, Wijngaard, Peter, Horton, Jay D, Taubel, Jorg, Brooks, Ashley, Fernando, Chamikara, Kauffman, Robert S, Kallend, David, Vaishnaw, Akshay, Simon, Amy

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The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals von Moon, Young-Ah, Liang, Guosheng, Xie, Xuefen, Frank-Kamenetsky, Maria, Fitzgerald, Kevin, Koteliansky, Victor, Brown, Michael S., Goldstein, Joseph L., Horton, Jay D.

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PCSK9: a convertase that coordinates LDL catabolism von Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.

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Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation von Kim, Chai-Wan, Addy, Carol, Kusunoki, Jun, Anderson, Norma N., Deja, Stanislaw, Fu, Xiaorong, Burgess, Shawn C., Li, Cai, Ruddy, Marcie, Chakravarthy, Manu, Previs, Steve, Milstein, Stuart, Fitzgerald, Kevin, Kelley, David E., Horton, Jay D.

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Acetate Dependence of Tumors von Comerford, Sarah A., Huang, Zhiguang, Du, Xinlin, Wang, Yun, Cai, Ling, Witkiewicz, Agnes K., Walters, Holly, Tantawy, Mohammed N., Fu, Allie, Manning, H. Charles, Horton, Jay D., Hammer, Robert E., McKnight, Steven L., Tu, Benjamin P.

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Molecular mediators of hepatic steatosis and liver injury von Browning, Jeffrey D, Horton, Jay D

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Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism von Ferris, Heather A., Perry, Rachel J., Moreira, Gabriela V., Shulman, Gerald I., Horton, Jay D., Kahn, C. Ronald

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Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice[S] von Linden, Albert G., Li, Shili, Choi, Hwa Y., Fang, Fei, Fukasawa, Masashi, Uyeda, Kosaku, Hammer, Robert E., Horton, Jay D., Engelking, Luke J., Liang, Guosheng

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A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice[S] von Duarte, Joao A.G., Carvalho, Filipa, Pearson, Mackenzie, Horton, Jay D., Browning, Jeffrey D., Jones, John G., Burgess, Shawn C.

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MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels von Goedeke, Leigh, Rotllan, Noemi, Canfrán-Duque, Alberto, Aranda, Juan F, Ramírez, Cristina M, Araldi, Elisa, Lin, Chin-Sheng, Anderson, Norma N, Wagschal, Alexandre, de Cabo, Rafael, Horton, Jay D, Lasunción, Miguel A, Näär, Anders M, Suárez, Yajaira, Fernández-Hernando, Carlos

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Genetic and Metabolic Determinants of Plasma PCSK9 Levels von Lakoski, Susan G., Lagace, Thomas A., Cohen, Jonathan C., Horton, Jay D., Hobbs, Helen H.

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver von Horton, Jay D, Goldstein, Joseph L, Brown, Michael S

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CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL von Bartuzi, Paulina, Billadeau, Daniel D., Favier, Robert, Rong, Shunxing, Dekker, Daphne, Fedoseienko, Alina, Fieten, Hille, Wijers, Melinde, Levels, Johannes H., Huijkman, Nicolette, Kloosterhuis, Niels, van der Molen, Henk, Brufau, Gemma, Groen, Albert K., Elliott, Alison M., Kuivenhoven, Jan Albert, Plecko, Barbara, Grangl, Gernot, McGaughran, Julie, Horton, Jay D., Burstein, Ezra, Hofker, Marten H., van de Sluis, Bart

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Molecular basis for LDL receptor recognition by PCSK9 von Kwon, Hyock Joo, Lagace, Thomas A, McNutt, Markey C, Horton, Jay D, Deisenhofer, Johann

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The impact of endotrophin on the progression of chronic liver disease von Kim, Min, Lee, Changhu, Seo, Dae Yun, Lee, Hyojung, Horton, Jay D., Park, Jiyoung, Scherer, Philipp E.

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Binding of Proprotein Convertase Subtilisin/Kexin Type 9 to Epidermal Growth Factor-like Repeat A of Low Density Lipoprotein Receptor Decreases Receptor Recycling and Increases Deg... von Zhang, Da-Wei, Lagace, Thomas A., Garuti, Rita, Zhao, Zhenze, McDonald, Meghan, Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.

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Fasting reduces plasma proprotein convertase, subtilisin/kexin type 9 and cholesterol biosynthesis in humans von Browning, Jeffrey D., Horton, Jay D.

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Catalytic Activity Is Not Required for Secreted PCSK9 to Reduce Low Density Lipoprotein Receptors in HepG2 Cells von McNutt, Markey C., Lagace, Thomas A., Horton, Jay D.

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