Nine-Step Enantioselective Total Synthesis of (−)-Vincorine von Horning, Benjamin D, MacMillan, David W. C

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Proteome-wide covalent ligand discovery in native biological systems von Backus, Keriann M., Correia, Bruno E., Lum, Kenneth M., Forli, Stefano, Horning, Benjamin D., González-Páez, Gonzalo E., Chatterjee, Sandip, Lanning, Bryan R., Teijaro, John R., Olson, Arthur J., Wolan, Dennis W., Cravatt, Benjamin F.

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Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine von Kavanagh, Madeline E., Horning, Benjamin D., Khattri, Roli, Roy, Nilotpal, Lu, Justine P., Whitby, Landon R., Ye, Elva, Brannon, Jaclyn C., Parker, Albert, Chick, Joel M., Eissler, Christie L., Wong, Ashley J., Rodriguez, Joe L., Rodiles, Socorro, Masuda, Kim, Teijaro, John R., Simon, Gabriel M., Patricelli, Matthew P., Cravatt, Benjamin F.

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Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer von Bar-Peled, Liron, Kemper, Esther K., Suciu, Radu M., Vinogradova, Ekaterina V., Backus, Keriann M., Horning, Benjamin D., Paul, Thomas A., Ichu, Taka-Aki, Svensson, Robert U., Olucha, Jose, Chang, Max W., Kok, Bernard P., Zhu, Zhou, Ihle, Nathan T., Dix, Melissa M., Jiang, Ping, Hayward, Matthew M., Saez, Enrique, Shaw, Reuben J., Cravatt, Benjamin F.

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Chemoproteomic profiling and discovery of protein electrophiles in human cells von Matthews, Megan L., He, Lin, Horning, Benjamin D., Olson, Erika J., Correia, Bruno E., Yates, John R., Dawson, Philip E., Cravatt, Benjamin F.

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Chemical Proteomic Profiling of Human Methyltransferases von Horning, Benjamin D, Suciu, Radu M, Ghadiri, Darian A, Ulanovskaya, Olesya A, Matthews, Megan L, Lum, Kenneth M, Backus, Keriann M, Brown, Steven J, Rosen, Hugh, Cravatt, Benjamin F

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Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ von Lee, Hsin-Yu, Suciu, Radu M., Horning, Benjamin D., Vinogradova, Ekaterina V., Ulanovskaya, Olesya A., Cravatt, Benjamin F.

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Author Correction: Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine von Kavanagh, Madeline E., Horning, Benjamin D., Khattri, Roli, Roy, Nilotpal, Lu, Justine P., Whitby, Landon R., Ye, Elva, Brannon, Jaclyn C., Parker, Albert, Chick, Joel M., Eissler, Christie L., Wong, Ashley J., Rodriguez, Joe L., Rodiles, Socorro, Masuda, Kim, Teijaro, John R., Simon, Gabriel M., Patricelli, Matthew P., Cravatt, Benjamin F.

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THE PREPARATION OF (2R,5S)-2-t-BUTYL-3,5-DIMETHYLIMIDAZOLIDIN-4-ONE

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1-(([1, 1',-BIPHENYL]-2-YL)SULFONYL)-4-FLUORO-N-(3-(METHYLSULFONYL)ALLYL)PIPERIDINE-4-CARBOXAMIDE DERIVATIVES AS RAS-PI3K MODULATORS FOR THE TREATMENT OF E.G. CANCER von HORNING, Benjamin, TAMIYA, Junko, COOK, Brian, BEDKE, Karl, PAN, Chung-Mao, ONDOZABAL, Hideki Miyatake, BERRY, Cynthia

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COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K von HORNING, Benjamin, TAMIYA, Junko, MALMSTROM, Robert, BEDKE, Karl, PAN, Chung-Mao

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COMPOUNDS SELECTIVE FOR JAK1 AND METHODS OF USE von COOK, Brian Nicholas, HORNING, Benjamin, KIKUCHI, Shota, PATRICELLI, Matthew, LAM, Betty, ROY, Nilotpal

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Cereblon modulators and uses thereof von Vinogradova, Ekaterina, Simon, Gabe, Patricelli, Matthew, Stamos, Dean, Cravatt, Benjamin F, Horning, Benjamin, Weinstein, David

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PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS von ROGNESS, Don, GREEN, Jason, KIKUCHI, Shota, HORNING, Benjamin, LAMB, Kelsey, WEINSTEIN, David, BURGESS, Larry, MALMSTROM, Robert, OWYANG, Zachary, LAM, Betty

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IN VIVO ENGINEERED CEREBLON PROTEIN von CRAVATT, Benjamin F, STAMOS, Dean, SIMON, Gabe, HORNING, Benjamin, WEINSTEIN, David, PATRICELLI, Matthew

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PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS von Malmstrom, Robert, Kikuchi, Shota, Rogness, Don, Burgess, Larry, Lamb, Kelsey, Owyang, Zachary, Green, Jason, Horning, Benjamin, Lam, Betty, Weinstein, David

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PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS von Malmstrom, Robert, Owyang, Zach, Kikuchi, Shota, Rogness, Don, Burgess, Larry, Lamb, Kelsey, Green, Jason, Horning, Benjamin, Lam, Betty, Weinstein, David

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PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS von ROGNESS, Don, OWYANG, Zach, GREEN, Jason, KIKUCHI, Shota, HORNING, Benjamin, LAMB, Kelsey, WEINSTEIN, David, BURGESS, Larry, MALMSTROM, Robert, LAM, Betty

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COMPOUNDS SELECTIVE FOR JAK1 AND METHODS OF USE von COOK, Brian Nicholas, HORNING, Benjamin, KIKUCHI, Shota, PATRICELLI, Matthew, LAM, Betty, ROY, Nilotpal

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CEREBLON MODULATORS AND USES THEREOF von CRAVATT, Benjamin F, STAMOS, Dean, SIMON, Gabe, HORNING, Benjamin, VINOGRADOVA, Ekaterina, WEINSTEIN, David, PATRICELLI, Matthew

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