Extreme Polygenicity of Complex Traits Is Explained by Negative Selection von O'Connor, Luke J., Schoech, Armin P., Hormozdiari, Farhad, Gazal, Steven, Patterson, Nick, Price, Alkes L.

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Colocalization of GWAS and eQTL Signals Detects Target Genes von Hormozdiari, Farhad, van de Bunt, Martijn, Segrè, Ayellet V., Li, Xiao, Joo, Jong Wha J., Bilow, Michael, Sul, Jae Hoon, Sankararaman, Sriram, Pasaniuc, Bogdan, Eskin, Eleazar

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Functionally informed fine-mapping and polygenic localization of complex trait heritability von Weissbrod, Omer, Hormozdiari, Farhad, Benner, Christian, Cui, Ran, Ulirsch, Jacob, Gazal, Steven, Schoech, Armin P., van de Geijn, Bryce, Reshef, Yakir, Márquez-Luna, Carla, O’Connor, Luke, Pirinen, Matti, Finucane, Hilary K., Price, Alkes L.

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Identifying causal variants by fine mapping across multiple studies von LaPierre, Nathan, Taraszka, Kodi, Huang, Helen, He, Rosemary, Hormozdiari, Farhad, Eskin, Eleazar

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Integrating functional data to prioritize causal variants in statistical fine-mapping studies von Kichaev, Gleb, Yang, Wen-Yun, Lindstrom, Sara, Hormozdiari, Farhad, Eskin, Eleazar, Price, Alkes L, Kraft, Peter, Pasaniuc, Bogdan

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DeepNull models non-linear covariate effects to improve phenotypic prediction and association power von McCaw, Zachary R., Colthurst, Thomas, Yun, Taedong, Furlotte, Nicholas A., Carroll, Andrew, Alipanahi, Babak, McLean, Cory Y., Hormozdiari, Farhad

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Chromosome conformation elucidates regulatory relationships in developing human brain von Won, Hyejung, de la Torre-Ubieta, Luis, Stein, Jason L., Parikshak, Neelroop N., Huang, Jerry, Opland, Carli K., Gandal, Michael J., Sutton, Gavin J., Hormozdiari, Farhad, Lu, Daning, Lee, Changhoon, Eskin, Eleazar, Voineagu, Irina, Ernst, Jason, Geschwind, Daniel H.

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Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation von Gamazon, Eric R., Segrè, Ayellet V., van de Bunt, Martijn, Wen, Xiaoquan, Xi, Hualin S., Hormozdiari, Farhad, Ongen, Halit, Konkashbaev, Anuar, Derks, Eske M., Aguet, François, Quan, Jie, Nicolae, Dan L., Eskin, Eleazar, Kellis, Manolis, Getz, Gad, McCarthy, Mark I., Dermitzakis, Emmanouil T., Cox, Nancy J., Ardlie, Kristin G.

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mrsFAST: a cache-oblivious algorithm for short-read mapping von Sahinalp, S Cenk, Hach, Faraz, Hormozdiari, Fereydoun, Alkan, Can, Hormozdiari, Farhad, Birol, Inanc, Eichler, Evan E

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Exploiting the GTEx resources to decipher the mechanisms at GWAS loci von Barbeira, Alvaro N., Bonazzola, Rodrigo, Gamazon, Eric R., Liang, Yanyu, Park, YoSon, Kim-Hellmuth, Sarah, Wang, Gao, Jiang, Zhuoxun, Zhou, Dan, Hormozdiari, Farhad, Liu, Boxiang, Rao, Abhiram, Hamel, Andrew R., Pividori, Milton D., Aguet, Francois, Bastarache, Lisa, Jordan, Daniel M., Verbanck, Marie, Do, Ron, Stephens, Matthew, Ardlie, Kristin, McCarthy, Mark, Montgomery, Stephen B., Segre, Ayellet V., Brown, Christopher D., Lappalainen, Tuuli, Wen, Xiaoquan, Im, Hae Kyung

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Accelerating read mapping with FastHASH von Xin, Hongyi, Lee, Donghyuk, Hormozdiari, Farhad, Yedkar, Samihan, Mutlu, Onur, Alkan, Can

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Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits von Hormozdiari, Farhad, Gazal, Steven, van de Geijn, Bryce, Finucane, Hilary K., Ju, Chelsea J.-T., Loh, Po-Ru, Schoech, Armin, Reshef, Yakir, Liu, Xuanyao, O’Connor, Luke, Gusev, Alexander, Eskin, Eleazar, Price, Alkes L.

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Dissecting the genetic basis of comorbid epilepsy phenotypes in neurodevelopmental disorders von Chow, Julie, Jensen, Matthew, Amini, Hajar, Hormozdiari, Farhad, Penn, Osnat, Shifman, Sagiv, Girirajan, Santhosh, Hormozdiari, Fereydoun

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Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx von Gay, Nicole R., Gloudemans, Michael, Antonio, Margaret L., Abell, Nathan S., Balliu, Brunilda, Park, YoSon, Martin, Alicia R., Musharoff, Shaila, Rao, Abhiram S., Aguet, Francois, Barbeira, Alvaro N., Bonazzola, Rodrigo, Hormozdiari, Farhad, Ardlie, Kristin G., Brown, Christopher D., Im, Hae Kyung, Lappalainen, Tuuli, Wen, Xiaoquan, Montgomery, Stephen B.

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Evaluating the informativeness of deep learning annotations for human complex diseases von Dey, Kushal K., van de Geijn, Bryce, Kim, Samuel Sungil, Hormozdiari, Farhad, Kelley, David R., Price, Alkes L.

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MARS: leveraging allelic heterogeneity to increase power of association testing von Hormozdiari, Farhad, Jung, Junghyun, Eskin, Eleazar, Joo, Jong Wha J.

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Leveraging allelic imbalance to refine fine-mapping for eQTL studies von Zou, Jennifer, Hormozdiari, Farhad, Jew, Brandon, Castel, Stephane E, Lappalainen, Tuuli, Ernst, Jason, Sul, Jae Hoon, Eskin, Eleazar

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Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk von Reshef, Yakir A., Finucane, Hilary K., Kelley, David R., Gusev, Alexander, Kotliar, Dylan, Ulirsch, Jacob C., Hormozdiari, Farhad, Nasser, Joseph, O’Connor, Luke, van de Geijn, Bryce, Loh, Po-Ru, Grossman, Sharon R., Bhatia, Gaurav, Gazal, Steven, Palamara, Pier Francesco, Pinello, Luca, Patterson, Nick, Adams, Ryan P., Price, Alkes L

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Applicability Domains for Classification Problems: Benchmarking of Distance to Models for Ames Mutagenicity Set von Sushko, Iurii, Novotarskyi, Sergii, Körner, Robert, Pandey, Anil Kumar, Cherkasov, Artem, Li, Jiazhong, Gramatica, Paola, Hansen, Katja, Schroeter, Timon, Müller, Klaus-Robert, Xi, Lili, Liu, Huanxiang, Yao, Xiaojun, Öberg, Tomas, Hormozdiari, Farhad, Dao, Phuong, Sahinalp, Cenk, Todeschini, Roberto, Polishchuk, Pavel, Artemenko, Anatoliy, Kuz’min, Victor, Martin, Todd M, Young, Douglas M, Fourches, Denis, Muratov, Eugene, Tropsha, Alexander, Baskin, Igor, Horvath, Dragos, Marcou, Gilles, Muller, Christophe, Varnek, Alexander, Prokopenko, Volodymyr V, Tetko, Igor V

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Demographically-Based Evaluation of Genomic Regions under Selection in Domestic Dogs von Freedman, Adam H, Schweizer, Rena M, Ortega-Del Vecchyo, Diego, Han, Eunjung, Davis, Brian W, Gronau, Ilan, Silva, Pedro M, Galaverni, Marco, Fan, Zhenxin, Marx, Peter, Lorente-Galdos, Belen, Ramirez, Oscar, Hormozdiari, Farhad, Alkan, Can, Vilà, Carles, Squire, Kevin, Geffen, Eli, Kusak, Josip, Boyko, Adam R, Parker, Heidi G, Lee, Clarence, Tadigotla, Vasisht, Siepel, Adam, Bustamante, Carlos D, Harkins, Timothy T, Nelson, Stanley F, Marques-Bonet, Tomas, Ostrander, Elaine A, Wayne, Robert K, Novembre, John

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