High content screening analysis of phospholipidosis: Validation of a 96-well assay with CHO-K1 and HepG2 cells for the prediction of in vivo based phospholipidosis von van de Water, F.M., Havinga, J., Ravesloot, W.T., Horbach, G.J.M.J., Schoonen, W.G.E.J.

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Genotoxicity of hormonal steroids von Joosten, H.F.P, van Acker, F.A.A, van den Dobbelsteen, D.J, Horbach, G.J.M.J, Krajnc, E.I

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Development of human cytochrome P450-expressing cell lines : application mutagenicity testing of ochratoxin A von DE GROENE, E. M, HASSING, I. G. A. M, BLOM, M. J, SEINEN, W, FINK-GREMMELS, J, HORBACH, G. J

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Structure dependent induction of CYP1A by polychlorinated biphenyls in hepatocytes of male castrated pigs von Van der Burght, Aafje S.A.M., Tysklind, Mats, Andersson, Patrik L., Horbach, G.Jean, van den Berg, Martin

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Structure-Dependent Induction of CYP1A by Polychlorinated Biphenyls in Hepatocytes of Cynomolgus Monkeys (Macaca fascicularis) von van der Burght, Aafje S.A.M., Clijsters, Peter J., Horbach, G.Jean, Andersson, Patrik L., Tysklind, Mats, van den Berg, Martin

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Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons von Kappers, Wendela A, van Och, François M.M, de Groene, Els M, Horbach, G.Jean

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In vitro complex formation and inhibition of hepatic cytochrome P450 activity by different macrolides and tiamulin in goats and cattle von ZWEERS-ZEILMAKER, W.M, VAN MIERT, A.S.J.P.A.M, HORBACH, G.J, WITKAMP, R.F

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Modulation of gene expression in autoimmune disease and aging by food restriction and dietary lipids von Fernandes, G, Venkatraman, J, Khare, A, Horbach, G.J.M.J, Friedrichs, W

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Characterization of CYP1A in hepatocytes of cynomolgus monkeys (Macaca fascicularis) and induction by different substituted polychlorinated biphenyls (PCBs) von VAN DER BURGHT, A. S. A. M, KREIKAMP, A. P, HORBACH, G. J, SEINEN, W, VAN DEN BERG, M

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In vitro and in vivo oxidative biotransformation in the West-African dwarf goat (Caprus hircus aegagrus): substrate activities and effects of inducers von Zweers-Zeilmaker, W.M, Batzias, J, Maas, R.F.M, Horbach, G.J, Miert, A.S.J.P.A.M. van, Witkamp, R.F

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The effect of age on inducibility of various types of rat liver cytochrome P-450 von Horbach, G. J. M., Van Asten, J. G., Rietjens, I. M. C. M., Kremers, P., Van Bezooijen, C. F. A.

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Stable Expression of Human Cytochrome P450 3A4 in Conjunction with Human NADPH-Cytochrome P450 Oxidoreductase in V79 Chinese Hamster Cells von Schneider, Anneliese, Schmalix, Wolfgang A., Siruguri, Vasanthi, de Groene, Els M., Horbach, G.Jean, Kleingeist, Britta, Lang, Dieter, Böcker, Ronald, Belloc, Claire, Beaune, Philippe, Greim, Helmut, Doehmer, Johannes

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A NIH/3T3 cell line stably expressing human cytochrome P450-3A4 used in combination with a lacZ′ shuttle vector to study mutagenicity von De Groene, Els M., Seinen, Willem, Horbach, G.J.M.Jean

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Mutagenicity and genotoxicity of the mycotoxin ochratoxin A von de Groene, Els M., Jahn, Andrea, Horbach, G.Jean, Fink-Gremmels, Johanna

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Hepatic cytochrome P450 induction in goats: Effects of model inducers on the metabolism of alkoxyresorufins, testosterone and ethylmorphine, and on apoprotein and mRNA levels von Van't Klooster, Gerben A.E., Horbach, G.J.M.Jean, Natsuhori, Masahiro, Blaauboer, Bas J., Noordhoek, Jan, Van Miert, Adelbert S.J.P.A.M.

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cDNA and Deduced Amino Acid Sequence of a Dwarf Goat Liver Cytochrome P450 Fragment Belonging to the CYP2C Gene Subfamily von Zeilmaker, W.M., Vantklooster, G.A.E., Gremmelsgehrmann, J.F., Vanmiert, A.S.J.P.A.M., Horbach, G.J.M.J.

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Transgenic cell lines and changes in gene function and expression: Useful tools in toxicity testing? von Horbach, G.J.M.J., De Groene, E.M.

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Isolation of a bovine full length cytochrome P450 (CYP3A) cDNA sequence and its functional expression in V79 cells von Natsuhori, Masahiro, van Raak, Marcel, Ligtenberg, Margot, Kleij, Livio, ten Berge, Derk, Zweers-Zeilmaker, Wilma M., de Groene, Els M., van Miert, Adelbert S.J.P.A.M., Witkamp, Renger F., Horbach, G.Jean

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Uniform procedure of (1)H NMR analysis of rat urine and toxicometabonomics Part II: comparison of NMR profiles for classification of hepatotoxicity von Schoonen, Willem G E J, Kloks, Cathelijne P A M, Ploemen, Jan-Peter H T M, Smit, Martin J, Zandberg, Pieter, Horbach, G Jean, Mellema, Jan-Remt, Thijssen-Vanzuylen, Carol, Tas, Albert C, van Nesselrooij, Joop H J, Vogels, Jack T W E

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Effects of non steroidal anti-inflammatory drugs and sulfonamides on hepatic cytochrome P4502C activity in vitro in goats and cattle von Zweers-Zeilmaker, W.M., Horbach, G.J., Witkamp, R.F.

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