Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas von Yamagishi, Makoto, Hori, Makoto, Fujikawa, Dai, Ohsugi, Takeo, Honma, Daisuke, Adachi, Nobuaki, Katano, Harutaka, Hishima, Tsunekazu, Kobayashi, Seiichiro, Nakano, Kazumi, Nakashima, Makoto, Iwanaga, Masako, Utsunomiya, Atae, Tanaka, Yuetsu, Okada, Seiji, Tsukasaki, Kunihiro, Tobinai, Kensei, Araki, Kazushi, Watanabe, Toshiki, Uchimaru, Kaoru

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CDKN1C‐mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib von Kagiyama, Yuki, Fujita, Shuhei, Shima, Yutaka, Yamagata, Kazutsune, Katsumoto, Takuo, Nakagawa, Makoto, Honma, Daisuke, Adachi, Nobuaki, Araki, Kazushi, Kato, Ayako, Inaki, Koichiro, Ono, Yoshimasa, Fukuhara, Suguru, Kobayashi, Yukio, Tobinai, Kensei, Kitabayashi, Issay

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Novel orally bioavailable EZH1/2 dual inhibitors with greater antitumor efficacy than an EZH2 selective inhibitor von Honma, Daisuke, Kanno, Osamu, Watanabe, Jun, Kinoshita, Junzo, Hirasawa, Makoto, Nosaka, Emi, Shiroishi, Machiko, Takizawa, Takeshi, Yasumatsu, Isao, Horiuchi, Takao, Nakao, Akira, Suzuki, Keisuke, Yamasaki, Tomonori, Nakajima, Katsuyoshi, Hayakawa, Miho, Yamazaki, Takanori, Yadav, Ajay Singh, Adachi, Nobuaki

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Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myeloma von Nakagawa, Makoto, Fujita, Shuhei, Katsumoto, Takuo, Yamagata, Kazutsune, Ogawara, Yoko, Hattori, Ayuna, Kagiyama, Yuki, Honma, Daisuke, Araki, Kazushi, Inoue, Tatsuya, Kato, Ayako, Inaki, Koichiro, Wada, Chisa, Ono, Yoshimasa, Yamamoto, Masahide, Miura, Osamu, Nakashima, Yasuharu, Kitabayashi, Issay

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EZH1/2 dual inhibitors suppress HTLV-1-infected cell proliferation and hyperimmune response in HTLV-1-associated myelopathy von Koseki, Akihito, Araya, Natsumi, Yamagishi, Makoto, Yamauchi, Junji, Yagishita, Naoko, Takao, Naoki, Takahashi, Katsunori, Kunitomo, Yasuo, Honma, Daisuke, Araki, Kazushi, Uchimaru, Kaoru, Sato, Tomoo, Yamano, Yoshihisa

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Light-driven Hydrogen Production by a Hybrid Complex of a [NiFe]-Hydrogenase and the Cyanobacterial Photosystem I von Ihara, Masaki, Nishihara, Hirofumi, Yoon, Ki-Seok, Lenz, Oliver, Friedrich, Bärbel, Nakamoto, Hitoshi, Kojima, Kouji, Honma, Daisuke, Kamachi, Toshiaki, Okura, Ichiro

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Development and Molecular Analysis of Synthetic Lethality By Targeting EZH1 and EZH2 in Non-Hodgkin Lymphomas von Yamagishi, Makoto, Hori, Makoto, Fujikawa, Dai, Honma, Daisuke, Adachi, Nobuaki, Ohsugi, Takeo, Nakano, Kazumi, Nakashima, Makoto, Kobayashi, Seiichiro, Iwanaga, Masako, Utsunomiya, Atae, Okada, Seiji, Tsukasaki, Kunihiro, Tobinai, Kensei, Araki, Kazushi, Watanabe, Toshiki, Uchimaru, Kaoru

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Synthesis and biological evaluation of pyrethroid insecticide-derivatives as a chemical inducer for Bdnf mRNA expression in neurons von Matsuya, Yuji, Ihara, Daisuke, Fukuchi, Mamoru, Honma, Daisuke, Itoh, Kiyoshi, Tabuchi, Akiko, Nemoto, Hideo, Tsuda, Masaaki

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A Novel Method for the Production of Transgenic Cloned Pigs: Electroporation-Mediated Gene Transfer to Non-Cultured Cells and Subsequent Selection with Puromycin von WATANABE, Satoshi, IWAMOTO, Masaki, SUZUKI, Shun-Ichi, FUCHIMOTO, Daiichiro, HONMA, Daisuke, NAGAI, Takashi, HASHIMOTO, Michiko, YAZAKI, Satoko, SATO, Masahiro, ONISHI, Akira

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Ultrastructural stability under high temperature or intensive light stress conferred by a small heat shock protein in cyanobacteria von Nitta, Koji, Suzuki, Nobuaki, Honma, Daisuke, Kaneko, Yasuko, Nakamoto, Hitoshi

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Targeting EZH1/2 to Restore Chemosensitivity in Dormant Myeloid Leukemia Stem Cells von Chang, Kyung Hee, Basyal, Mahesh, Alaniz, Zoe, Honma, Daisuke, Tsutsumi, Shinji, Dos Santos, Cedric E., Daver, Naval, Andreeff, Michael

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STRENGTH DEVELOPMENT OF 300 N/MM2 CLASS ULTRA-HIGH STRENGTH GROUT DURING HEAT CONTROLLED CURING WITH ELEVATED TEMPERATURES von HONMA, Daisuke, KOJIMA, Masarou, NISHIWAKI, Tomoya, MIHASHI, Hirozo

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高流動・無収縮タイプコンクリートのアート壁への適用と壁ひずみの将来予測 von 井上, 和政, 小川, 亜希子, 本間, 大輔, 佐藤, 敏之, 岩清水, 隆, 齊藤, 和秀

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Abstract 4670: Identification of a possible therapeutic candidate for multiple myeloma based on dual inhibition of EZH1/EZH2 von Nakagawa, Makoto, Fujita, Shuhei, Honma, Daisuke, Araki, Kazushi, Kitabayashi, Issay

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PRC2-Mediated Apoptosis Evasion Is a Therapeutic Target of MDS/AML Harboring Inv(3)/t(3;3) and -7 von Kunimoto, Hiroyoshi, Miura, Ayaka, Sagisaka, Maiko, Ito, Mieko, Honma, Daisuke, Tsutsumi, Shinji, Sakuma, Takayuki, Ohashi, Takuma, Teranaka, Hiroshi, Ikeda, Junji, Toya, Takashi, Harada, Yuka, Doki, Noriko, Cai, Sheng F., Yoshimi, Akihide, Goto, Hiroaki, Levine, Ross L, Nakajima, Hideaki

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Interaction of a small heat shock protein with light-harvesting cyanobacterial phycocyanins under stress conditions von Nakamoto, Hitoshi, Honma, Daisuke

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EZH1/2 Dual Inhibitor Valemetostat Tosylate (DS-3201b) Acts Differently from EZH2 Selective Inhibitor on Epigenetic Landscape to Exert Greater Anti-Tumor Effect Against Diffuse Lar... von Banjo, Toshihiro, Hama, Yasuhiro, Nosaka, Emi, Takata, Yoshimi, Honma, Daisuke, Kitagawa, Mayumi, Yamamoto, Yuka, Wada, Chisa, Yoshida, Takanori, Lim, Kyungtaek, Okamoto, Atsushi, Sato, Erina, Katayama, Yumiko, Sato, Kazumi, Goto, Hiroki, Abe, Yuki

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STUDY ON OPTIMIZATION OF BINDERS TO ACHIEVE HIGH STRENGTH CONCRETE WITH DESIGN STANDARD STRENGTH OF 300 N/MM2 von KOJIMA, Masaro, HONMA, Daisuke, TSUJI, Daijiro, OKADA, Kazuhisa, KOYAMA, Tomoyuki

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Abstract 4672: Novel epigenetic approach to relapsed mantle cell lymphoma based on dual inhibition of EZH1/EZH2 von Fujita, Shuhei, Kagiyama, Yuki, Honma, Daisuke, Adachi, Nobuaki, Araki, Kazushi, Kitabayashi, Issay

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Nordic Walking Improve The Quality Of Life And Physical Function In Subjects With Hip Osteoarthritis: 278 Board #129 May 27, 9: 30 AM - 11: 00 AM von JIGAMI, HIROFUMI, SATO, NARITOSHI, HONMA, DAISUKE, ENDO, NAOTO

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