Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis von Yan, Minhong, Ridgway, John, Zhang, Gu, Wu, Yan, Stawicki, Scott, Liang, Wei-Ching, Chanthery, Yvan, Kowalski, Joe, Watts, Ryan J, Callahan, Christopher, Kasman, Ian, Singh, Mallika, Chien, May, Tan, Christine, Hongo, Jo-Anne S, de Sauvage, Fred, Plowman, Greg

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Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation von Wen, Xiaohui, Lai, Cary K., Evangelista, Marie, Hongo, Jo-Anne, de Sauvage, Frederic J., Scales, Suzie J.

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Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages von Wong, Kit, Valdez, Patricia A, Tan, Christine, Yeh, Sherry, Hongo, Jo-Anne, Ouyang, Wenjun

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Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling von Callow, Marinella G, Tran, Hoanh, Phu, Lilian, Lau, Ted, Lee, James, Sandoval, Wendy N, Liu, Peter S, Bheddah, Sheila, Tao, Janet, Lill, Jennie R, Hongo, Jo-Anne, Davis, David, Kirkpatrick, Donald S, Polakis, Paul, Costa, Mike

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Glycan Shifting on Hepatitis C Virus (HCV) E2 Glycoprotein Is a Mechanism for Escape from Broadly Neutralizing Antibodies von Pantua, Homer, Diao, Jingyu, Ultsch, Mark, Hazen, Meredith, Mathieu, Mary, McCutcheon, Krista, Takeda, Kentaro, Date, Shailesh, Cheung, Tommy K., Phung, Qui, Hass, Phil, Arnott, David, Hongo, Jo-Anne, Matthews, David J., Brown, Alex, Patel, Arvind H., Kelley, Robert F., Eigenbrot, Charles, Kapadia, Sharookh B.

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An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer von Bhakta, Sunil, Crocker, Lisa M, Chen, Yvonne, Hazen, Meredith, Schutten, Melissa M, Li, Dongwei, Kuijl, Coenraad, Ohri, Rachana, Zhong, Fiona, Poon, Kirsten A, Go, Mary Ann T, Cheng, Eric, Piskol, Robert, Firestein, Ron, Fourie-O'Donohue, Aimee, Kozak, Katherine R, Raab, Helga, Hongo, Jo-Anne, Sampath, Deepak, Dennis, Mark S, Scheller, Richard H, Polakis, Paul, Junutula, Jagath R

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A neutralizing anti-gH/gL monoclonal antibody is protective in the guinea pig model of congenital CMV infection von Auerbach, Marcy R, Yan, Donghong, Vij, Rajesh, Hongo, Jo-Anne, Nakamura, Gerald, Vernes, Jean-Michel, Meng, Y Gloria, Lein, Samantha, Chan, Pamela, Ross, Jed, Carano, Richard, Deng, Rong, Lewin-Koh, Nicholas, Xu, Min, Feierbach, Becket

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Expression pattern of the human FcRH/IRTA receptors in normal tissue and in B-chronic lymphocytic leukemia von Polson, Andrew G., Zheng, Bing, Elkins, Kristi, Chang, Wesley, Du, Changchun, Dowd, Patrick, Yen, Lulu, Tan, Christine, Hongo, Jo-Anne, Koeppen, Hartmut, Ebens, Allen

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Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma von Polson, Andrew G., Yu, Shang-Fan, Elkins, Kristi, Zheng, Bing, Clark, Suzanna, Ingle, Gladys S., Slaga, Dionysos S., Giere, Lynne, Du, Changchun, Tan, Christine, Hongo, Jo-Anne, Gogineni, Alvin, Cole, Mary J., Vandlen, Richard, Stephan, Jean-Philippe, Young, Judy, Chang, Wesley, Scales, Suzie J., Ross, Sarajane, Eaton, Dan, Ebens, Allen

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Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function von Storm, Elaine E., Durinck, Steffen, de Sousa e Melo, Felipe, Tremayne, Jarrod, Kljavin, Noelyn, Tan, Christine, Ye, Xiaofen, Chiu, Cecilia, Pham, Thinh, Hongo, Jo-Anne, Bainbridge, Travis, Firestein, Ron, Blackwood, Elizabeth, Metcalfe, Ciara, Stawiski, Eric W., Yauch, Robert L., Wu, Yan, de Sauvage, Frederic J.

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Plasmalemmal vesicle-associated protein (PLVAP) is expressed by tumour endothelium and is upregulated by vascular endothelial growth factor-A (VEGF) von Strickland, Laura A, Jubb, Adrian M, Hongo, Jo-Anne, Zhong, Fiona, Burwick, Jennifer, Fu, Ling, Frantz, Gretchen D, Koeppen, Hartmut

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In vivo effects of targeting CD79b with antibodies and antibody-drug conjugates von Zheng, Bing, Fuji, Reina N, Elkins, Kristi, Yu, Shang-Fan, Fuh, Franklin K, Chuh, Josefa, Tan, Christine, Hongo, Jo-Anne, Raab, Helga, Kozak, Katherine R, Williams, Marna, McDorman, Elena, Eaton, Dan, Ebens, Allen, Polson, Andrew G

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COP1 is a tumour suppressor that causes degradation of ETS transcription factors von Vitari, Alberto C., Leong, Kevin G., Newton, Kim, Yee, Cindy, O’Rourke, Karen, Liu, Jinfeng, Phu, Lilian, Vij, Rajesh, Ferrando, Ronald, Couto, Suzana S., Mohan, Sankar, Pandita, Ajay, Hongo, Jo-Anne, Arnott, David, Wertz, Ingrid E., Gao, Wei-Qiang, French, Dorothy M., Dixit, Vishva M.

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Phosphorylation of Dishevelled by Protein Kinase RIPK4 Regulates Wnt Signaling von Huang, XiaoDong, McGann, James C., Liu, Bob Y., Hannoush, Rami N., Lill, Jennie R., Pham, Victoria, Newton, Kim, Kakunda, Michael, Liu, Jinfeng, Yu, Christine, Hymowitz, Sarah G., Hongo, Jo-Anne, Wynshaw-Boris, Anthony, Polakis, Paul, Harland, Richard M., Dixit, Vishva M.

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PlGF Blockade Does Not Inhibit Angiogenesis during Primary Tumor Growth von Bais, Carlos, Wu, Xiumin, Yao, Jenny, Yang, Suya, Crawford, Yongping, McCutcheon, Krista, Tan, Christine, Kolumam, Ganesh, Vernes, Jean-Michel, Eastham-Anderson, Jeffrey, Haughney, Peter, Kowanetz, Marcin, Hagenbeek, Thijs, Kasman, Ian, Reslan, Hani Bou, Ross, Jed, Van Bruggen, Nick, Carano, Richard A.D., Meng, Yu-Ju Gloria, Hongo, Jo-Anne, Stephan, Jean- Philippe, Shibuya, Masabumi, Ferrara, Napoleone

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An improved and robust DNA immunization method to develop antibodies against extra-cellular loops of multi-transmembrane proteins von Hazen, Meredith, Bhakta, Sunil, Vij, Rajesh, Randle, Steven, Kallop, Dara, Chiang, Vicki, Hötzel, Isidro, Jaiswal, Bijay S, Ervin, Karen E, Li, Bing, Weimer, Robby M, Polakis, Paul, Scheller, Richard H, Junutula, Jagath R, Hongo, Jo-Anne S

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A Novel Type I Cytokine Receptor Is Expressed on Monocytes, Signals Proliferation, and Activates STAT-3 and STAT-5 von Ghilardi, Nico, Li, Ji, Hongo, Jo-Anne, Yi, Sothy, Gurney, Austin, de Sauvage, Frederic J.

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Tethered-variable CL bispecific IgG: an antibody platform for rapid bispecific antibody screening von Kim, Hok Seon, Dunshee, Diana Ronai, Yee, Angie, Tong, Raymond K, Kim, Ingrid, Farahi, Farzam, Hongo, Jo-Anne, Ernst, James A, Sonoda, Junichiro, Spiess, Christoph

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Induction of gp91-phox, a Component of the Phagocyte NADPH Oxidase, in Microglial Cells during Central Nervous System Inflammation von Green, Simon P., Cairns, Belinda, Rae, Julie, Errett-Baroncini, Carol, Hongo, Jo-Anne S., Erickson, Richard W., Curnutte, John T.

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An improved and robust DNA immunization method to develop antibodies against extracellular loops of multi-transmembrane proteins von Hazen, Meredith, Bhakta, Sunil, Vij, Rajesh, Randle, Steven, Kallop, Dara, Chiang, Vicki, Hötzel, Isidro, Jaiswal, Bijay S, Ervin, Karen E, Li, Bing, Weimer, Robby M, Polakis, Paul, Scheller, Richard H, Junutula, Jagath R, Hongo, Jo-Anne S

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