The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity von Casares, Laura, Moreno, Rita, Ali, Kevin X., Higgins, Maureen, Dayalan Naidu, Sharadha, Neill, Graham, Cassin, Lena, Kiib, Anders E., Svenningsen, Esben B., Minassi, Alberto, Honda, Tadashi, Poulsen, Thomas B., Wiel, Clotilde, Sayin, Volkan I., Dinkova-Kostova, Albena T., Olagnier, David, de la Vega, Laureano

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Downregulation of Keap1 Confers Features of a Fasted Metabolic State von Knatko, Elena V., Tatham, Michael H., Zhang, Ying, Castro, Cecilia, Higgins, Maureen, Dayalan Naidu, Sharadha, Leonardi, Chiara, de la Vega, Laureano, Honda, Tadashi, Griffin, Julian L., Hay, Ronald T., Dinkova-Kostova, Albena T.

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In Situ Observation of Thiol Michael Addition to a Reversible Covalent Drug in a Crystalline Sponge von Duplan, Vincent, Hoshino, Manabu, Li, Wei, Honda, Tadashi, Fujita, Makoto

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Reciprocal interactions between bile acids and gut microbiota in human liver diseases von Ikegami, Tadashi, Honda, Akira

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A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide production von HONDA, Tadashi, HONDA, Yukiko, FAVALORO, Frank G, GRIBBLE, Gordon W, SUH, Nanjoo, PLACE, Andrew E, RENDI, Mara H, SPORN, Michael B

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C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape von Dayalan Naidu, Sharadha, Muramatsu, Aki, Saito, Ryota, Asami, Soichiro, Honda, Tadashi, Hosoya, Tomonori, Itoh, Ken, Yamamoto, Masayuki, Suzuki, Takafumi, Dinkova-Kostova, Albena T.

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Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2) von Sharma, Ritu S, Harrison, David J, Kisielewski, Dorothy, Cassidy, Diane M, McNeilly, Alison D, Gallagher, Jennifer R, Walsh, Shaun V, Honda, Tadashi, McCrimmon, Rory J, Dinkova-Kostova, Albena T, Ashford, Michael L.J, Dillon, John F, Hayes, John D

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Author Correction: C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape von Dayalan Naidu, Sharadha, Muramatsu, Aki, Saito, Ryota, Asami, Soichiro, Honda, Tadashi, Hosoya, Tomonori, Itoh, Ken, Yamamoto, Masayuki, Suzuki, Takafumi, Dinkova-Kostova, Albena T.

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Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates von Bartolome, Fernando, Esteras, Noemi, Martin-Requero, Angeles, Boutoleau-Bretonniere, Claire, Vercelletto, Martine, Gabelle, Audrey, Le Ber, Isabelle, Honda, Tadashi, Dinkova-Kostova, Albena T., Hardy, John, Carro, Eva, Abramov, Andrey Y.

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Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer von MacLeod, A Kenneth, Acosta-Jimenez, Lourdes, Coates, Philip J, McMahon, Michael, Carey, Frank A, Honda, Tadashi, Henderson, Colin J, Wolf, C Roland

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Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response von Ryan, Dylan G., Knatko, Elena V., Casey, Alva M., Hukelmann, Jens L., Dayalan Naidu, Sharadha, Brenes, Alejandro J., Ekkunagul, Thanapon, Baker, Christa, Higgins, Maureen, Tronci, Laura, Nikitopolou, Efterpi, Honda, Tadashi, Hartley, Richard C., O’Neill, Luke A.J., Frezza, Christian, Lamond, Angus I., Abramov, Andrey Y., Arthur, J. Simon C., Cantrell, Doreen A., Murphy, Michael P., Dinkova-Kostova, Albena T.

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Inhibition of glycogen synthase kinase-3 enhances NRF2 protein stability, nuclear localisation and target gene transcription in pancreatic beta cells von Patibandla, Chinmai, van Aalten, Lidy, Dinkova-Kostova, Albena T., Honda, Tadashi, Cuadrado, Antonio, Fernández-Ginés, Raquel, McNeilly, Alison D., Hayes, John D., Cantley, James, Sutherland, Calum

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Antidepressant effects of TBE-31 and MCE-1, the novel Nrf2 activators, in an inflammation model of depression von Yao, Wei, Zhang, Ji-Chun, Ishima, Tamaki, Ren, Qian, Yang, Chun, Dong, Chao, Ma, Min, Saito, Akira, Honda, Tadashi, Hashimoto, Kenji

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Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans von Knatko, Elena V, Ibbotson, Sally H, Zhang, Ying, Higgins, Maureen, Fahey, Jed W, Talalay, Paul, Dawe, Robert S, Ferguson, James, Huang, Jeffrey T-J, Clarke, Rosemary, Zheng, Suqing, Saito, Akira, Kalra, Sukirti, Benedict, Andrea L, Honda, Tadashi, Proby, Charlotte M, Dinkova-Kostova, Albena T

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Extremely Potent Triterpenoid Inducers of the Phase 2 Response: Correlations of Protection against Oxidant and Inflammatory Stress von Dinkova-Kostova, Albena T., Liby, Karen T., Stephenson, Katherine K., Holtzclaw, W. David, Gao, Xiangqun, Suh, Nanjoo, Williams, Charlotte, Risingsong, Renee, Honda, Tadashi, Gribble, Gordon W., Sporn, Michael B., Talalay, Paul

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Recent progress in the strategic incorporation of fluorine into medicinally active compounds von Haranahalli, Krupanandan, Honda, Tadashi, Ojima, Iwao

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Quantification of Trace Elements in Certified Reference Materials of Aerosol, Sediment, Ash and Crude Oil by Microwave Digestion and ICP-MS von Honda, Masatoshi, Hioki, Tadashi

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Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes von Yates, Melinda S, Tauchi, Masafumi, Katsuoka, Fumiki, Flanders, Kathleen C, Liby, Karen T, Honda, Tadashi, Gribble, Gordon W, Johnson, Delinda A, Johnson, Jeffrey A, Burton, Neal C, Guilarte, Tomás R, Yamamoto, Masayuki, Sporn, Michael B, Kensler, Thomas W

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Design, Synthesis, and Biological Evaluations of Asymmetric Bow-Tie PAMAM Dendrimer-Based Conjugates for Tumor-Targeted Drug Delivery von Wang, Tao, Zhang, Yaozhong, Wei, Longfei, Teng, Yuhan G, Honda, Tadashi, Ojima, Iwao

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The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-κB activation through direct inhibition of IκB kinase β von Yore, Mark M., Liby, Karen T., Honda, Tadashi, Gribble, Gordon W., Sporn, Michael B.

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