CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL von Hagner, Patrick R., Man, Hon-Wah, Fontanillo, Celia, Wang, Maria, Couto, Suzana, Breider, Mike, Bjorklund, Chad, Havens, Courtney G., Lu, Gang, Rychak, Emily, Raymon, Heather, Narla, Rama Krishna, Barnes, Leo, Khambatta, Gody, Chiu, Hsiling, Kosek, Jolanta, Kang, Jian, Amantangelo, Michael D., Waldman, Michelle, Lopez-Girona, Antonia, Cai, Ti, Pourdehnad, Michael, Trotter, Matthew, Daniel, Thomas O., Schafer, Peter H., Klippel, Anke, Thakurta, Anjan, Chopra, Rajesh, Gandhi, Anita K.

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The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions von Lu, Ling, Payvandi, Faribourz, Wu, Lei, Zhang, Ling-Hua, Hariri, Robert J, Man, Hon-Wah, Chen, Roger S., Muller, George W., Hughes, Christopher C.W., Stirling, David I., Schafer, Peter H., Bartlett, J. Blake

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A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos von Matyskiela, Mary E, Zhang, Weihong, Man, Hon-Wah, Muller, George, Khambatta, Godrej, Baculi, Frans, Hickman, Matthew, LeBrun, Laurie, Pagarigan, Barbra, Carmel, Gilles, Lu, Chin-Chun, Lu, Gang, Riley, Mariko, Satoh, Yoshitaka, Schafer, Peter, Daniel, Thomas O, Carmichael, James, Cathers, Brian E, Chamberlain, Philip P

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Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity von Ruchelman, Alexander L., Man, Hon-Wah, Zhang, Weihong, Chen, Roger, Capone, Lori, Kang, Jian, Parton, Anastasia, Corral, Laura, Schafer, Peter H., Babusis, Darius, Moghaddam, Mehran F., Tang, Yang, Shirley, Michael A., Muller, George W.

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1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4 von Ruchelman, Alexander L., Man, Hon-Wah, Chen, Roger, Liu, Wei, Lu, Ling, Cedzik, Dorota, Zhang, Ling, Leisten, Jim, Collette, Alice, Narla, Rama Krishna, Raymon, Heather K., Muller, George W.

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Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiester... von MAN, Hon-Wah, SCHAFER, Peter, BABUSIS, Darius M, CHEN, Roger, STIRLING, Dave, MULLER, George W, LU MIN WONG, PATTERSON, Rebecca T, CORRAL, Laura G, RAYMON, Heather, BLEASE, Kate, LEISTEN, Jim, SHIRLEY, Michael A, YANG TANG

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Asymmetric Synthesis of Stegobinone via Boronic Ester Chemistry von Matteson, Donald S, Man, Hon-Wah, Ho, Oliver C

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A Highly Enantioselective and Diastereoselective Synthesis of Cyclobutanes via Boronic Esters von Man, Hon-Wah, Hiscox, William C, Matteson, Donald S

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Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells von Mouratidis, Petros X E, Colston, Kay W, Bartlett, Jake Blake, Muller, George W, Man, Hon-Wah, Stirling, David, Dalgleish, Angus G

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Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors:  Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies von Jadhav, Prabhakar K, Woerner, Francis J, Lam, Patrick Y. S, Hodge, C. Nicholas, Eyermann, Charles J, Man, Hon-Wah, Daneker, Wayne F, Bacheler, Lee T, Rayner, Marlene M, Meek, James L, Erickson-Viitanen, Susan, Jackson, David A, Calabrese, Joseph C, Schadt, Margaret, Chang, Chong-Hwan

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α-Fluoro-substituted thalidomide analogues von MAN, Hon-Wah, CORRAL, Laura G, STIRLING, David I, MULLER, George W

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Enantioselective Capture and Retroracemization of (1-Bromoalkyl)boronic Esters by an N-Propanoyloxazolidinone Enolate and Iodide Ion von Matteson, Donald S, Man, Hon-Wah

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A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins von MARRIOTT, J. Blake, CLARKE, Ian A, DALGLEISH, Angus G, CZAJKA, Anna, DREDGE, Keith, CHILDS, Kay, MAN, Hon-Wah, SCHAFER, Peter, GOVINDA, Sowmya, MULLER, George W, STIRLING, David I

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Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues von PREHN, John L, LANDERS, Carol, MULLER, George W, MAN, Hon-Wah, STIRLING, David I, TARGAN, Stephan R

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Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS von Krönke, Jan, Fink, Emma C., Hollenbach, Paul W., MacBeth, Kyle J., Hurst, Slater N., Udeshi, Namrata D., Chamberlain, Philip P., Mani, D. R., Man, Hon Wah, Gandhi, Anita K., Svinkina, Tanya, Schneider, Rebekka K., McConkey, Marie, Järås, Marcus, Griffiths, Elizabeth, Wetzler, Meir, Bullinger, Lars, Cathers, Brian E., Carr, Steven A., Chopra, Rajesh, Ebert, Benjamin L.

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Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition von GEE, Michael S, MAKONNEN, Sosina, AL-KOFAHI, Khalid, ROYSAM, Badri, PAYVANDI, Faribourz, MAN, Hon-Wah, MULLER, George W, LEE, William M. F

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Hydrolysis of Substituted 1,3,2-Dioxaborolanes and an Asymmetric Synthesis of a Differentially Protected syn,syn-3-Methyl-2,4-hexanediol von Matteson, Donald S, Man, Hon-Wah

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Synthesis of 7-membered cyclic oxamides: Novel HIV-1 protease inhibitors von Jadhav, Prabhakar K, Man, Hon-Wah

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Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiester... von Man, Hon-Wah, Schafer, Peter, Wong, Lu Min, Patterson, Rebecca T, Corral, Laura G, Raymon, Heather, Blease, Kate, Leisten, Jim, Shirley, Michael A, Tang, Yang, Babusis, Darius M, Chen, Roger, Stirling, Dave, Muller, George W

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Direct Synthesis of [α-[(tert-Butoxycarbonyl)amino]alkyl]- boronates from (α-Haloalkyl)boronates von Jadhav, Prabhakar K., Man, Hon-Wah

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