The choroid plexus is an important circadian clock component von Myung, Jihwan, Schmal, Christoph, Hong, Sungho, Tsukizawa, Yoshiaki, Rose, Pia, Zhang, Yong, Holtzman, Michael J., De Schutter, Erik, Herzel, Hanspeter, Bordyugov, Grigory, Takumi, Toru

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The role of airway epithelial cells and innate immune cells in chronic respiratory disease von Holtzman, Michael J., Byers, Derek E., Alexander-Brett, Jennifer, Wang, Xinyu

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SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function von Winkler, Emma S., Bailey, Adam L., Kafai, Natasha M., Nair, Sharmila, McCune, Broc T., Yu, Jinsheng, Fox, Julie M., Chen, Rita E., Earnest, James T., Keeler, Shamus P., Ritter, Jon H., Kang, Liang-I, Dort, Sarah, Robichaud, Annette, Head, Richard, Holtzman, Michael J., Diamond, Michael S.

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The microbial metabolite desaminotyrosine protects from influenza through type I interferon von Steed, Ashley L., Christophi, George P., Kaiko, Gerard E., Sun, Lulu, Goodwin, Victoria M., Jain, Umang, Esaulova, Ekaterina, Artyomov, Maxim N., Morales, David J., Holtzman, Michael J., Boon, Adrianus C. M., Lenschow, Deborah J., Stappenbeck, Thaddeus S.

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A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2 von Hassan, Ahmed O., Kafai, Natasha M., Dmitriev, Igor P., Fox, Julie M., Smith, Brittany K., Harvey, Ian B., Chen, Rita E., Winkler, Emma S., Wessel, Alex W., Case, James Brett, Kashentseva, Elena, McCune, Broc T., Bailey, Adam L., Zhao, Haiyan, VanBlargan, Laura A., Dai, Ya-Nan, Ma, Meisheng, Adams, Lucas J., Shrihari, Swathi, Danis, Jonathan E., Gralinski, Lisa E., Hou, Yixuan J., Schäfer, Alexandra, Kim, Arthur S., Keeler, Shamus P., Weiskopf, Daniela, Baric, Ralph S., Holtzman, Michael J., Fremont, Daved H., Curiel, David T., Diamond, Michael S.

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A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies von Hassan, Ahmed O., Case, James Brett, Winkler, Emma S., Thackray, Larissa B., Kafai, Natasha M., Bailey, Adam L., McCune, Broc T., Fox, Julie M., Chen, Rita E., Alsoussi, Wafaa B., Turner, Jackson S., Schmitz, Aaron J., Lei, Tingting, Shrihari, Swathi, Keeler, Shamus P., Fremont, Daved H., Greco, Suellen, McCray, Paul B., Perlman, Stanley, Holtzman, Michael J., Ellebedy, Ali H., Diamond, Michael S.

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Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice von Case, James Brett, Rothlauf, Paul W., Chen, Rita E., Kafai, Natasha M., Fox, Julie M., Smith, Brittany K., Shrihari, Swathi, McCune, Broc T., Harvey, Ian B., Keeler, Shamus P., Bloyet, Louis-Marie, Zhao, Haiyan, Ma, Meisheng, Adams, Lucas J., Winkler, Emma S., Holtzman, Michael J., Fremont, Daved H., Whelan, Sean P.J., Diamond, Michael S.

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Toxoplasma Effector Recruits the Mi-2/NuRD Complex to Repress STAT1 Transcription and Block IFN-γ-Dependent Gene Expression von Olias, Philipp, Etheridge, Ronald D., Zhang, Yong, Holtzman, Michael J., Sibley, L. David

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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma von Demehri, Shadmehr, Morimoto, Mitsuru, Holtzman, Michael J, Kopan, Raphael

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Target Selection for the SDSS-IV APOGEE-2 Survey von Zasowski, G., Cohen, R. E., Chojnowski, S. D., Santana, F., Oelkers, R. J., Andrews, B., Beaton, R. L., Bender, C., Bird, J. C., Bovy, J., Carlberg, J. K., Covey, K., Cunha, K., Dell'Agli, F., Fleming, Scott W., Frinchaboy, P. M., García-Hernández, D. A., Harding, P., Holtzman, J., Johnson, J. A., Kollmeier, J. A., Majewski, S. R., Mészáros, Sz, Munn, J., Muñoz, R. R., Ness, M. K., Nidever, D. L., Poleski, R., Román-Zúñiga, C., Shetrone, M., Simon, J. D., Smith, V. V., Sobeck, J. S., Stringfellow, G. S., Szigetiáros, L., Tayar, J., Troup, N.

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A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice von Sodhi, Chhinder P, Nguyen, Jenny, Yamaguchi, Yukihiro, Werts, Adam D, Lu, Peng, Ladd, Mitchell R, Fulton, William B, Kovler, Mark L, Wang, Sanxia, Prindle, Jr, Thomas, Zhang, Yong, Lazartigues, Eric D, Holtzman, Michael J, Alcorn, John F, Hackam, David J, Jia, Hongpeng

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BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes von Ehlers, A, Xie, W, Agapov, E, Brown, S, Steinberg, D, Tidwell, R, Sajol, G, Schutz, R, Weaver, R, Yu, H, Castro, M, Bacharier, L B, Wang, X, Holtzman, M J, Haspel, J A

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SARS-CoV-2 Causes Lung Infection without Severe Disease in Human ACE2 Knock-In Mice von Winkler, Emma S, Chen, Rita E, Alam, Fahmida, Yildiz, Soner, Case, James Brett, Uccellini, Melissa B, Holtzman, Michael J, Garcia-Sastre, Adolfo, Schotsaert, Michael, Diamond, Michael S

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Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development von Xu, Huixin, Fame, Ryann M., Sadegh, Cameron, Sutin, Jason, Naranjo, Christopher, Della Syau, Cui, Jin, Shipley, Frederick B., Vernon, Amanda, Gao, Fan, Zhang, Yong, Holtzman, Michael J., Heiman, Myriam, Warf, Benjamin C., Lin, Pei-Yi, Lehtinen, Maria K.

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Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation von Siller, Saul S, Sharma, Himanshu, Li, Shuai, Yang, June, Zhang, Yong, Holtzman, Michael J, Winuthayanon, Wipawee, Colognato, Holly, Holdener, Bernadette C, Li, Feng-Qian, Takemaru, Ken-Ichi

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Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo von Gitlin, Leonid, Benoit, Loralyn, Song, Christina, Cella, Marina, Gilfillan, Susan, Holtzman, Michael J, Colonna, Marco

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TREM-2 promotes macrophage survival and lung disease after respiratory viral infection von Wu, Kangyun, Byers, Derek E, Jin, Xiaohua, Agapov, Eugene, Alexander-Brett, Jennifer, Patel, Anand C, Cella, Marina, Gilfilan, Susan, Colonna, Marco, Kober, Daniel L, Brett, Tom J, Holtzman, Michael J

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Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms von Kober, Daniel L, Alexander-Brett, Jennifer M, Karch, Celeste M, Cruchaga, Carlos, Colonna, Marco, Holtzman, Michael J, Brett, Thomas J

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Alternatively Activated Macrophages and Airway Disease von Byers, Derek E., MD, PhD, Holtzman, Michael J., MD, FCCP

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PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection von Zhang, Yong, Mao, Dailing, Roswit, William T, Jin, Xiaohua, Patel, Anand C, Patel, Dhara A, Agapov, Eugene, Wang, Zhepeng, Tidwell, Rose M, Atkinson, Jeffrey J, Huang, Guangming, McCarthy, Ronald, Yu, Jinsheng, Yun, Nadezhda E, Paessler, Slobodan, Lawson, T Glen, Omattage, Natalie S, Brett, Tom J, Holtzman, Michael J

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