Death receptor agonist therapies for cancer, which is the right TRAIL? von Holland, Pamela M

Volltext

Targeting Apo2L/TRAIL receptors by soluble Apo2L/TRAIL von Holland, Pamela M

Volltext

Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity von Graves, Jonathan D., Kordich, Jennifer J., Huang, Tzu-Hsuan, Piasecki, Julia, Bush, Tammy L., Sullivan, Timothy, Foltz, Ian N., Chang, Wesley, Douangpanya, Heather, Dang, Thu, O’Neill, Jason W., Mallari, Rommel, Zhao, Xiaoning, Branstetter, Daniel G., Rossi, John M., Long, Alexander M., Huang, Xin, Holland, Pamela M.

Volltext

Ligand-Based Targeting of Apoptosis in Cancer: The Potential of Recombinant Human Apoptosis Ligand 2/Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (rhApo2L/TRAIL) von ASHKENAZI, Avi, HOLLAND, Pamela, GAIL ECKHARDT, S

Volltext

Death Receptor Agonists as a Targeted Therapy for Cancer von WIEZOREK, Jeffrey, HOLLAND, Pamela, GRAVES, Jonathan

Volltext

Therapeutic potential of cis-targeting bispecific antibodies von Oslund, Rob C., Holland, Pamela M., Lesley, Scott A., Fadeyi, Olugbeminiyi O.

Volltext

Povetacicept, an Enhanced Dual APRIL/BAFF Antagonist That Modulates B Lymphocytes and Pathogenic Autoantibodies for the Treatment of Lupus and Other B Cell–Related Autoimmune Disea... von Evans, Lawrence S., Lewis, Katherine E., DeMonte, Daniel, Bhandari, Janhavi G., Garrett, Logan B., Kuijper, Joseph L., Ardourel, Daniel, Wolfson, Martin F., Debrot, Susan, Mudri, Sherri, Kleist, Kayla, Griffin, Luana L., Hebb, LuAnne, Sanderson, Russell J., Wang, NingXin, Seaberg, Michelle, Chunyk, Allison G., Yang, Jing, Hong, Youji, Maria, Zahra, Messenheimer, David J., Holland, Pamela M., Peng, Stanford L., Rixon, Mark W., Dillon, Stacey R.

Volltext

Endogenous IL-27 during toxoplasmosis limits early monocyte responses and their inflammatory activation by pathological T cells von Aldridge, Daniel L, Moodley, Devapregasan, Park, Jeongho, Phan, Anthony T, Rausch, Matthew, White, Kerry F, Ren, Yue, Golin, Karin, Radaelli, Enrico, Kedl, Ross, Holland, Pamela M, Hill, Jonathan, Hunter, Christopher A

Volltext

Non‐Redundant Roles of T Cell Costimulation Pathways in Inflammatory Arthritis Revealed by Dual Blockade of ICOS and CD28 with Acazicolcept (ALPN‐101) von Dillon, Stacey R., Evans, Lawrence S., Lewis, Katherine E., Debrot, Susan, Blair, Tiffany C., Mudri, Sherri, Kleist, Kayla, Levin, Steven D., Bhandari, Janhavi G., Garrett, Logan, Wolfson, Martin F., Holland, Pamela M., Rixon, Mark W., Peng, Stanford L.

Volltext

The Fully human anti-CD47 antibody SRF231 exerts dual-mechanism antitumor activity via engagement of the activating receptor CD32a von Peluso, Marisa O, Adam, Ammar, Armet, Caroline M, Zhang, Li, O’Connor, Rachel W, Lee, Benjamin H, Lake, Andrew C, Normant, Emmanuel, Chappel, Scott C, Hill, Jonathan A, Palombella, Vito J, Holland, Pamela M, Paterson, Alison M

Volltext

Potential Oncogenic Effect of the MERTK-Dependent Apoptotic-Cell Clearance Pathway in Starry-Sky B-Cell Lymphoma von Farnworth-McHugh, Sarah, Barth, Nicole, Melville, Lynsey, Paterson, Margaret, Lynch, Catherine, Holland, Pamela, Dransfield, Ian, Gregory, Christopher

Volltext

RIP4 Regulates Epidermal Differentiation and Cutaneous Inflammation von Rountree, Ryan B., Willis, Cynthia R., Dinh, Huyen, Blumberg, Hal, Bailey, Keith, Dean, Charles, Peschon, Jacques J., Holland, Pamela M.

Volltext

5-HT2A receptor signalling through phospholipase D1 associated with its C-terminal tail von Barclay, Zoë, Dickson, Louise, Robertson, Derek N, Johnson, Melanie S, Holland, Pamela J, Rosie, Roberta, Sun, Liting, Fleetwood-Walker, Sue, Lutz, Eve M, Mitchell, Rory

Volltext

Combined therapy with the RANKL inhibitor RANK-Fc and rhApo2L/TRAIL/dulanermin reduces bone lesions and skeletal tumor burden in a model of breast cancer skeletal metastasis von Holland, Pamela M., Miller, Robert, Jones, Jon, Douangpanya, Heather, Piasecki, Julia, Roudier, Martine, Dougall, William C.

Volltext

33 Development of a clinical ex vivo assay for the assessment of therapeutic CD28 costimulatory pathway engagement von Gudgeon, Chelsea, Maurer, Mark, Means, Gary, Mudri, Sherri, Blanchfield, Lori, Yang, Jing, Dillon, Stacey, Holland, Pamela, Goldberg, Zelanna, Peng, Stanford

Volltext

493 Tired and hungry: a potential role for CD47 in T cell exhaustion von Mangarin, Levi, Liu, Cailian, Zappasodi, Roberta, Holland, Pamela, Wolchok, Jedd, Merghoub, Taha, Weng, Chien-Huan, Schroder, David

Volltext

726 SRF114 is a fully human, CCR8 selective IgG1 antibody that induces destruction of tumor Tregs through ADCC von Lake, Andrew, Warren, Michael, Das, Sonia, Wells, Christopher, Scrivens, Maria, Smith, Ernest, Palombella, Vito, Etemad-Gilbertson, Bijan, Holland, Pamela, Dulak, Austin

Volltext

Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathwa... von Holtmann, Helmut, Winzen, Reinhard, Holland, Pamela, Eickemeier, Solveig, Hoffmann, Elke, Wallach, David, Malinin, Nikolai L., Cooper, Jonathan A., Resch, Klaus, Kracht, Michael

Volltext

RIP4 Is an Ankyrin Repeat-Containing Kinase Essential for Keratinocyte Differentiation von Holland, Pamela M., Willis, Cynthia R., Kanaly, Suzanne, Glaccum, Moira B., Warren, Annjanette S., Charrier, Keith, Murison, J.Greg, Derry, Jonathan M.J., Virca, G.Duke, Bird, Timothy A., Peschon, Jacques J.

Volltext

Selective Interaction of ARF1 with the Carboxy-Terminal Tail Domain of the 5-HT2A Receptor von Robertson, Derek N, Johnson, Melanie S, Moggach, Louise O, Holland, Pamela J, Lutz, Eve M, Mitchell, Rory

Volltext