Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression von Gao, Pan, Lyu, Qing, Ghanam, Amr R, Lazzarotto, Cicera R, Newby, Gregory A, Zhang, Wei, Choi, Mihyun, Slivano, Orazio J, Holden, Kevin, Walker, 2nd, John A, Kadina, Anastasia P, Munroe, Rob J, Abratte, Christian M, Schimenti, John C, Liu, David R, Tsai, Shengdar Q, Long, Xiaochun, Miano, Joseph M

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Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen von Mac Kain, Alice, Maarifi, Ghizlane, Aicher, Sophie-Marie, Arhel, Nathalie, Baidaliuk, Artem, Munier, Sandie, Donati, Flora, Vallet, Thomas, Tran, Quang Dinh, Hardy, Alexandra, Chazal, Maxime, Porrot, Françoise, OhAinle, Molly, Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Zimmer, Gert, Simon-Lorière, Etienne, Bruel, Timothée, Schwartz, Olivier, van der Werf, Sylvie, Jouvenet, Nolwenn, Nisole, Sébastien, Vignuzzi, Marco, Roesch, Ferdinand

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Persistence of Borrelia burgdorferi following Antibiotic Treatment in Mice von HODZIC, Emir, SUNLIAN FENG, HOLDEN, Kevin, FREET, Kimberly J, BARTHOLD, Stephen W

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Exploring the frontiers of science in Western China von Holden, Kevin

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Chinese physicists set to unveil conceptual designs for the globe’s most advanced circular collider von Holden, Kevin

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Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses von Wang, Ruofan, Simoneau, Camille R., Kulsuptrakul, Jessie, Bouhaddou, Mehdi, Travisano, Katherine A., Hayashi, Jennifer M., Carlson-Stevermer, Jared, Zengel, James R., Richards, Christopher M., Fozouni, Parinaz, Oki, Jennifer, Rodriguez, Lauren, Joehnk, Bastian, Walcott, Keith, Holden, Kevin, Sil, Anita, Carette, Jan E., Krogan, Nevan J., Ott, Melanie, Puschnik, Andreas S.

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Coinfection with Anaplasma phagocytophilum Alters Borrelia burgdorferi Population Distribution in C3H/HeN Mice von Holden, Kevin, Hodzic, Emir, Feng, Sunlian, Freet, Kimberly J, Lefebvre, Rance B, Barthold, Stephen W

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Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases von Yarnall, Matthew T. N., Ioannidi, Eleonora I., Schmitt-Ulms, Cian, Krajeski, Rohan N., Lim, Justin, Villiger, Lukas, Zhou, Wenyuan, Jiang, Kaiyi, Garushyants, Sofya K., Roberts, Nathaniel, Zhang, Liyang, Vakulskas, Christopher A., Walker, John A., Kadina, Anastasia P., Zepeda, Adrianna E., Holden, Kevin, Ma, Hong, Xie, Jun, Gao, Guangping, Foquet, Lander, Bial, Greg, Donnelly, Sara K., Miyata, Yoshinari, Radiloff, Daniel R., Henderson, Jordana M., Ujita, Andrew, Abudayyeh, Omar O., Gootenberg, Jonathan S.

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In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels von Rothgangl, Tanja, Dennis, Melissa K., Lin, Paulo J. C., Oka, Rurika, Witzigmann, Dominik, Villiger, Lukas, Qi, Weihong, Hruzova, Martina, Kissling, Lucas, Lenggenhager, Daniela, Borrelli, Costanza, Egli, Sabina, Frey, Nina, Bakker, Noëlle, Walker, John A., Kadina, Anastasia P., Victorov, Denis V., Pacesa, Martin, Kreutzer, Susanne, Kontarakis, Zacharias, Moor, Andreas, Jinek, Martin, Weissman, Drew, Stoffel, Markus, van Boxtel, Ruben, Holden, Kevin, Pardi, Norbert, Thöny, Beat, Häberle, Johannes, Tam, Ying K., Semple, Sean C., Schwank, Gerald

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Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells von Méndez-Mancilla, Alejandro, Wessels, Hans-Hermann, Legut, Mateusz, Kadina, Anastasia, Mabuchi, Megumu, Walker, John, Robb, G. Brett, Holden, Kevin, Sanjana, Neville E.

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The globalization of universities and science in Southern China von Holden, Kevin

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Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication von Williams, Caroline G., Jureka, Alexander S., Silvas, Jesus A., Nicolini, Anthony M., Chvatal, Stacie A., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Basler, Christopher F.

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Exploring the Frontiers of Science in Western China von Holden, Kevin

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BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2 von Samelson, Avi J., Tran, Quang Dinh, Robinot, Rémy, Carrau, Lucia, Rezelj, Veronica V., Kain, Alice Mac, Chen, Merissa, Ramadoss, Gokul N., Guo, Xiaoyan, Lim, Shion A., Lui, Irene, Nuñez, James K., Rockwood, Sarah J., Wang, Jianhui, Liu, Na, Carlson-Stevermer, Jared, Oki, Jennifer, Maures, Travis, Holden, Kevin, Weissman, Jonathan S., Wells, James A., Conklin, Bruce R., TenOever, Benjamin R., Chakrabarti, Lisa A., Vignuzzi, Marco, Tian, Ruilin, Kampmann, Martin

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Generation of precision preclinical cancer models using regulated in vivo base editing von Katti, Alyna, Vega-Pérez, Adrián, Foronda, Miguel, Zimmerman, Jill, Zafra, Maria Paz, Granowsky, Elizabeth, Goswami, Sukanya, Gardner, Eric E., Diaz, Bianca J., Simon, Janelle M., Wuest, Alexandra, Luan, Wei, Fernandez, Maria Teresa Calvo, Kadina, Anastasia P., Walker, John A., Holden, Kevin, Lowe, Scott W., Sánchez Rivera, Francisco J., Dow, Lukas E.

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Broad-spectrum CRISPR-mediated inhibition of SARS-CoV-2 variants and endemic coronaviruses in vitro von Zeng, Leiping, Liu, Yanxia, Nguyenla, Xammy Huu, Abbott, Timothy R., Han, Mengting, Zhu, Yanyu, Chemparathy, Augustine, Lin, Xueqiu, Chen, Xinyi, Wang, Haifeng, Rane, Draven A., Spatz, Jordan M., Jain, Saket, Rustagi, Arjun, Pinsky, Benjamin, Zepeda, Adrianna E., Kadina, Anastasia P., Walker, John A., Holden, Kevin, Temperton, Nigel, Cochran, Jennifer R., Barron, Annelise E., Connolly, Michael D., Blish, Catherine A., Lewis, David B., Stanley, Sarah A., La Russa, Marie F., Qi, Lei S.

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SIMULIIDAE von Holden, Kevin

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URSUS ARCTOS von Holden, Kevin

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MIRROR von Holden, Kevin

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Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2 von Chen, Irene P., Longbotham, James E., McMahon, Sarah, Suryawanshi, Rahul K., Khalid, Mir M., Taha, Taha Y., Tabata, Takako, Hayashi, Jennifer M., Soveg, Frank W., Carlson-Stevermer, Jared, Gupta, Meghna, Zhang, Meng Yao, Lam, Victor L., Li, Yang, Yu, Zanlin, Titus, Erron W., Diallo, Amy, Oki, Jennifer, Holden, Kevin, Krogan, Nevan, Fujimori, Danica Galonić, Ott, Melanie

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