Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression von Gao, Pan, Lyu, Qing, Ghanam, Amr R, Lazzarotto, Cicera R, Newby, Gregory A, Zhang, Wei, Choi, Mihyun, Slivano, Orazio J, Holden, Kevin, Walker, 2nd, John A, Kadina, Anastasia P, Munroe, Rob J, Abratte, Christian M, Schimenti, John C, Liu, David R, Tsai, Shengdar Q, Long, Xiaochun, Miano, Joseph M

Volltext

Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen von Mac Kain, Alice, Maarifi, Ghizlane, Aicher, Sophie-Marie, Arhel, Nathalie, Baidaliuk, Artem, Munier, Sandie, Donati, Flora, Vallet, Thomas, Tran, Quang Dinh, Hardy, Alexandra, Chazal, Maxime, Porrot, Françoise, OhAinle, Molly, Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Zimmer, Gert, Simon-Lorière, Etienne, Bruel, Timothée, Schwartz, Olivier, van der Werf, Sylvie, Jouvenet, Nolwenn, Nisole, Sébastien, Vignuzzi, Marco, Roesch, Ferdinand

Volltext

Persistence of Borrelia burgdorferi following Antibiotic Treatment in Mice von HODZIC, Emir, SUNLIAN FENG, HOLDEN, Kevin, FREET, Kimberly J, BARTHOLD, Stephen W

Volltext

Broad-spectrum CRISPR-mediated inhibition of SARS-CoV-2 variants and endemic coronaviruses in vitro von Zeng, Leiping, Liu, Yanxia, Nguyenla, Xammy Huu, Abbott, Timothy R., Han, Mengting, Zhu, Yanyu, Chemparathy, Augustine, Lin, Xueqiu, Chen, Xinyi, Wang, Haifeng, Rane, Draven A., Spatz, Jordan M., Jain, Saket, Rustagi, Arjun, Pinsky, Benjamin, Zepeda, Adrianna E., Kadina, Anastasia P., Walker, John A., Holden, Kevin, Temperton, Nigel, Cochran, Jennifer R., Barron, Annelise E., Connolly, Michael D., Blish, Catherine A., Lewis, David B., Stanley, Sarah A., La Russa, Marie F., Qi, Lei S.

Volltext

Exploring the frontiers of science in Western China von Holden, Kevin

Volltext

Chinese physicists set to unveil conceptual designs for the globe’s most advanced circular collider von Holden, Kevin

Volltext

Coinfection with Anaplasma phagocytophilum Alters Borrelia burgdorferi Population Distribution in C3H/HeN Mice von Holden, Kevin, Hodzic, Emir, Feng, Sunlian, Freet, Kimberly J, Lefebvre, Rance B, Barthold, Stephen W

Volltext

Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses von Wang, Ruofan, Simoneau, Camille R., Kulsuptrakul, Jessie, Bouhaddou, Mehdi, Travisano, Katherine A., Hayashi, Jennifer M., Carlson-Stevermer, Jared, Zengel, James R., Richards, Christopher M., Fozouni, Parinaz, Oki, Jennifer, Rodriguez, Lauren, Joehnk, Bastian, Walcott, Keith, Holden, Kevin, Sil, Anita, Carette, Jan E., Krogan, Nevan J., Ott, Melanie, Puschnik, Andreas S.

Volltext

Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases von Yarnall, Matthew T. N., Ioannidi, Eleonora I., Schmitt-Ulms, Cian, Krajeski, Rohan N., Lim, Justin, Villiger, Lukas, Zhou, Wenyuan, Jiang, Kaiyi, Garushyants, Sofya K., Roberts, Nathaniel, Zhang, Liyang, Vakulskas, Christopher A., Walker, John A., Kadina, Anastasia P., Zepeda, Adrianna E., Holden, Kevin, Ma, Hong, Xie, Jun, Gao, Guangping, Foquet, Lander, Bial, Greg, Donnelly, Sara K., Miyata, Yoshinari, Radiloff, Daniel R., Henderson, Jordana M., Ujita, Andrew, Abudayyeh, Omar O., Gootenberg, Jonathan S.

Volltext

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels von Rothgangl, Tanja, Dennis, Melissa K., Lin, Paulo J. C., Oka, Rurika, Witzigmann, Dominik, Villiger, Lukas, Qi, Weihong, Hruzova, Martina, Kissling, Lucas, Lenggenhager, Daniela, Borrelli, Costanza, Egli, Sabina, Frey, Nina, Bakker, Noëlle, Walker, John A., Kadina, Anastasia P., Victorov, Denis V., Pacesa, Martin, Kreutzer, Susanne, Kontarakis, Zacharias, Moor, Andreas, Jinek, Martin, Weissman, Drew, Stoffel, Markus, van Boxtel, Ruben, Holden, Kevin, Pardi, Norbert, Thöny, Beat, Häberle, Johannes, Tam, Ying K., Semple, Sean C., Schwank, Gerald

Volltext

The globalization of universities and science in Southern China von Holden, Kevin

Volltext

Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells von Méndez-Mancilla, Alejandro, Wessels, Hans-Hermann, Legut, Mateusz, Kadina, Anastasia, Mabuchi, Megumu, Walker, John, Robb, G. Brett, Holden, Kevin, Sanjana, Neville E.

Volltext

Microstructural characteristics and mechanical properties of additively manufactured Cu–10Sn alloys by laser powder bed fusion von Mehta, Abhishek, Zhou, Le, Hyer, Holden, Huynh, Thinh, Lu, Binghao, Graydon, Kevin, Drobner, Erica J., Park, Sun Hong, Sohn, Yongho

Volltext

High strength aluminum-cerium alloy processed by laser powder bed fusion von Hyer, Holden, Mehta, Abhishek, Graydon, Kevin, Kljestan, Nemanja, Knezevic, Marko, Weiss, David, McWilliams, Brandon, Cho, Kyu, Sohn, Yongho

Volltext

Exploring the Frontiers of Science in Western China von Holden, Kevin

Volltext

Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication von Williams, Caroline G., Jureka, Alexander S., Silvas, Jesus A., Nicolini, Anthony M., Chvatal, Stacie A., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Basler, Christopher F.

Volltext

Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond von Mathie, Alistair, Veale, Emma L, Cunningham, Kevin P, Holden, Robyn G, Wright, Paul D

Volltext

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2 von Samelson, Avi J., Tran, Quang Dinh, Robinot, Rémy, Carrau, Lucia, Rezelj, Veronica V., Kain, Alice Mac, Chen, Merissa, Ramadoss, Gokul N., Guo, Xiaoyan, Lim, Shion A., Lui, Irene, Nuñez, James K., Rockwood, Sarah J., Wang, Jianhui, Liu, Na, Carlson-Stevermer, Jared, Oki, Jennifer, Maures, Travis, Holden, Kevin, Weissman, Jonathan S., Wells, James A., Conklin, Bruce R., TenOever, Benjamin R., Chakrabarti, Lisa A., Vignuzzi, Marco, Tian, Ruilin, Kampmann, Martin

Volltext

Transgenic overexpression of mitofilin attenuates diabetes mellitus-associated cardiac and mitochondria dysfunction von Thapa, Dharendra, Nichols, Cody E, Lewis, Sara E, Shepherd, Danielle L, Jagannathan, Rajaganapathi, Croston, Tara L, Tveter, Kevin J, Holden, Anthony A, Baseler, Walter A, Hollander, John M

Volltext

MIRROR von Holden, Kevin

Volltext