Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys von Tao, Yunlong, Vermilyea, Scott C., Zammit, Matthew, Lu, Jianfeng, Olsen, Miles, Metzger, Jeanette M., Yao, Lin, Chen, Yuejun, Phillips, Sean, Holden, James E., Bondarenko, Viktoriya, Block, Walter F., Barnhart, Todd E., Schultz-Darken, Nancy, Brunner, Kevin, Simmons, Heather, Christian, Bradley T., Emborg, Marina E., Zhang, Su-Chun

Volltext

Induced Pluripotent Stem Cell-Derived Neural Cells Survive and Mature in the Nonhuman Primate Brain von Emborg, Marina E., Liu, Yan, Xi, Jiajie, Zhang, Xiaoqing, Yin, Yingnan, Lu, Jianfeng, Joers, Valerie, Swanson, Christine, Holden, James E., Zhang, Su-Chun

Volltext

Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys von Herzog, Christopher D., Dass, Biplob, Holden, James E., Stansell III, James, Gasmi, Mehdi, Tuszynski, Mark H., Bartus, Raymond T., Kordower, Jeffrey H.

Volltext

Neurodegeneration Prevented by Lentiviral Vector Delivery of GDNF in Primate Models of Parkinson's Disease von Kordower, Jeffrey H., Emborg, Marina E., Bloch, Jocelyne, Ma, Shuang Y., Chu, Yaping, Leventhal, Liza, McBride, Jodi, Chen, Er-Yun, Palfi, Stéphane, Roitberg, Ben Zion, Brown, W. Douglas, Holden, James E., Pyzalski, Robert, Taylor, Michael D., Carvey, Paul, Ling, ZaoDung, Trono, Didier, Hantraye, Philippe, Déglon, Nicole, Aebischer, Patrick

Volltext

Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism von Emborg, Marina E, Carbon, Maren, Holden, James E, During, Matthew J, Ma, Yilong, Tang, Chengke, Moirano, Jeffrey, Fitzsimons, Helen, Roitberg, Ben Z, Tuccar, Eray, Roberts, Andrew, Kaplitt, Michael G, Eidelberg, David

Volltext

PET Measures of D1, D2, and DAT Binding Are Associated With Heightened Tactile Responsivity in Rhesus Macaques: Implications for Sensory Processing Disorder von Schneider, Mary L, Moore, Colleen F, Ahlers, Elizabeth O, Barnhart, Todd E, Christian, Bradley T, DeJesus, Onofre T, Engle, Jonathan W, Holden, James E, Larson, Julie A, Moirano, Jeffrey M, Murali, Dhanabalan, Nickles, Robert J, Resch, Leslie M, Converse, Alexander K

Volltext

In vivo imaging of inflammation and oxidative stress in a nonhuman primate model of cardiac sympathetic neurodegeneration von Metzger, Jeanette M., Moore, Colleen F., Boettcher, Carissa A., Brunner, Kevin G., Fleddermann, Rachel A., Matsoff, Helen N., Resnikoff, Henry A., Bondarenko, Viktoriya, Kamp, Timothy J., Hacker, Timothy A., Barnhart, Todd E., Lao, Patrick J., Christian, Bradley T., Nickles, R. Jerry, Gallagher, Catherine L., Holden, James E., Emborg, Marina E.

Volltext

Positron emission tomography kinetic modeling algorithms for small animal dopaminergic system imaging von Topping, Geoffrey J., Dinelle, Katie, Kornelsen, Rick, McCormick, Siobhan, Holden, James E., Sossi, Vesna

Volltext

Metabolic rate in the right amygdala predicts negative affect in depressed patients von Abercrombie, Heather C, Schaefer, Stacey M, Larson, Christine L, Oakes, Terrence R, Lindgren, Kristen A, Holden, James E, Perlman, Scott B, Turski, Patrick A, Krahn, Dean D, Benca, Ruth M, Davidson, Richard J

Volltext

Nonuniform cardiac denervation observed by 11C-meta-hydroxyephedrine PET in 6-OHDA-treated monkeys von Joers, Valerie, Seneczko, Kailie, Goecks, Nichole C, Kamp, Timothy J, Hacker, Timothy A, Brunner, Kevin G, Engle, Jonathan W, Barnhart, Todd E, Nickles, R Jerome, Holden, James E, Emborg, Marina E

Volltext

Fetal Dose Estimates for 18F-Fluoro-L-Thymidine Using a Pregnant Monkey Model von Bartlett, Rachel M, Nickles, Robert J, Barnhart, Todd E, Christian, Bradley T, Holden, James E, DeJesus, Onofre T

Volltext

A Reversible Tracer Analysis Approach to the Study of Effective Dopamine Turnover von Sossi, Vesna, Doudet, Doris J., Holden, James E.

Volltext

Improved kinetic analysis of dynamic PET data with optimized HYPR-LR von Floberg, John M., Mistretta, Charles A., Weichert, Jamey P., Hall, Lance T., Holden, James E., Christian, Bradley T.

Volltext

In-vivo Measurement of LDOPA Uptake, Dopamine Reserve and Turnover in the Rat Brain Using [18F]FDOPA PET von Walker, Matthew D, Dinelle, Katherine, Kornelsen, Rick, McCormick, Siobhan, Mah, Chenoa, Holden, James E, Farrer, Matthew J, Stoessl, A Jon, Sossi, Vesna

Volltext

A method for partial volume correction of PET-imaged tumor heterogeneity using expectation maximization with a spatially varying point spread function von Barbee, David L, Flynn, Ryan T, Holden, James E, Nickles, Robert J, Jeraj, Robert

Volltext

Prenatal Stress Induces Increased Striatal Dopamine Transporter Binding in Adult Nonhuman Primates von Converse, Alexander K, Moore, Colleen F, Moirano, Jeffrey M, Ahlers, Elizabeth O, Larson, Julie A, Engle, Jonathan W, Barnhart, Todd E, Murali, Dhanabalan, Christian, Bradley T, DeJesus, Onofre T, Holden, James E, Nickles, Robert J, Schneider, Mary L

Volltext

In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease von Lee, Chong S., Samii, Ali, Sossi, Vesna, Ruth, Thomas J., Schulzer, Michael, Holden, James E., Wudel, Jess, Pal, Pramod K., De La Fuente-Fernandez, Raul, Calne, Donald B., Stoessl, A. Jon

Volltext

Moderate-Level Prenatal Alcohol Exposure Induces Sex Differences in Dopamine D1 Receptor Binding in Adult Rhesus Monkeys von Converse, Alexander K., Moore, Colleen F., Holden, James E., Ahlers, Elizabeth O., Moirano, Jeffrey M., Larson, Julie A., Resch, Leslie M., DeJesus, Onofre T., Barnhart, Todd E., Nickles, Robert J., Murali, Dhanabalan, Christian, Bradley T., Schneider, Mary L.

Volltext

High-Affinity Dopamine D2/D3 PET Radioligands 18F-Fallypride and 11C-FLB457: A Comparison of Kinetics in Extrastriatal Regions Using a Multiple-Injection Protocol von Vandehey, Nicholas T, Moirano, Jeffrey M, Converse, Alexander K, Holden, James E, Mukherjee, Jogesh, Murali, Dhanabalan, Nickles, R Jerry, Davidson, Richard J, Schneider, Mary L, Christian, Bradley T

Volltext

Dopamine transporter relation to levodopa-derived synaptic dopamine in a rat model of Parkinson's: an in vivo imaging study von Sossi, Vesna, Dinelle, Katherine, Topping, Geoffrey J, Holden, James E, Doudet, Doris, Schulzer, Michael, Ruth, Thomas J, Stoessl, A. Jon, de la Fuente-Fernandez, Raul

Volltext