Mouse gingival single-cell transcriptomic atlas identified a novel fibroblast subpopulation activated to guide oral barrier immunity in periodontitis von Kondo, Takeru, Gleason, Annie, Okawa, Hiroko, Hokugo, Akishige, Nishimura, Ichiro

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Therapeutic downregulation of neuronal PAS domain 2 ( Npas2 ) promotes surgical skin wound healing von Shibuya, Yoichiro, Hokugo, Akishige, Okawa, Hiroko, Kondo, Takeru, Khalil, Daniel, Wang, Lixin, Roca, Yvonne, Clements, Adam, Sasaki, Hodaka, Berry, Ella, Nishimura, Ichiro, Jarrahy, Reza

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Design and Synthesis of Cathepsin-K-Activated Osteoadsorptive Fluorogenic Sentinel (OFS) Probes for Detecting Early Osteoclastic Bone Resorption in a Multiple Myeloma Mouse Model von Richard, Eric T, Morinaga, Kenzo, Zheng, Yiying, Sundberg, Oskar, Hokugo, Akishige, Hui, Kimberly, Zhou, Yipin, Sasaki, Hodaka, Kashemirov, Boris A, Nishimura, Ichiro, McKenna, Charles E

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Augmentation of IFN-γ by bone marrow derived immune cells in the presence of severe suppression of IFN-γ in gingivae induced by zoledronic acid and denosumab in Hu-BLT mice model o... von Kaur, Kawaljit, Sun, Yujie, Kanayama, Keiichi, Morinaga, Kenzo, Hokugo, Akishige, Nishimura, Ichiro, Jewett, Anahid

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Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene dipho... von Okawa, Hiroko, Kondo, Takeru, Hokugo, Akishige, Cherian, Philip, Campagna, Jesus J, Lentini, Nicholas A, Sung, Eric C, Chiang, Samantha, Lin, Yi-Ling, Ebetino, Frank H, John, Varghese, Sun, Shuting, McKenna, Charles E, Nishimura, Ichiro

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Rescue bisphosphonate treatment of alveolar bone improves extraction socket healing and reduces osteonecrosis in zoledronate-treated mice von Hokugo, Akishige, Kanayama, Keiichi, Sun, Shuting, Morinaga, Kenzo, Sun, Yujie, Wu, QingQing, Sasaki, Hodaka, Okawa, Hiroko, Evans, Courtney, Ebetino, Frank H., Lundy, Mark W., Sadrerafi, Keivan, McKenna, Charles E., Nishimura, Ichiro

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Neuronal PAS Domain 2 (Npas2)‐Deficient Fibroblasts Accelerate Skin Wound Healing and Dermal Collagen Reconstruction von Sasaki, Hodaka, Hokugo, Akishige, Wang, Lixin, Morinaga, Kenzo, Ngo, John T., Okawa, Hiroko, Nishimura, Ichiro

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Stimulation of bone regeneration following the controlled release of water-insoluble oxysterol from biodegradable hydrogel von Hokugo, Akishige, Saito, Takashi, Li, Andrew, Sato, Keisuke, Tabata, Yasuhiko, Jarrahy, Reza

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Plasticity of Myeloid Cells during Oral Barrier Wound Healing and the Development of Bisphosphonate-related Osteonecrosis of the Jaw von Sun, Yujie, Kaur, Kawaljit, Kanayama, Keiichi, Morinaga, Kenzo, Park, Sil, Hokugo, Akishige, Kozlowska, Anna, McBride, William H., Li, Jun, Jewett, Anahid, Nishimura, Ichiro

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Titanium biomaterials with complex surfaces induced aberrant peripheral circadian rhythms in bone marrow mesenchymal stromal cells von Hassan, Nathaniel, McCarville, Kirstin, Morinaga, Kenzo, Mengatto, Cristiane M, Langfelder, Peter, Hokugo, Akishige, Tahara, Yu, Colwell, Christopher S, Nishimura, Ichiro

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Oral microbial extracellular DNA initiates periodontitis through gingival degradation by fibroblast-derived cathepsin K in mice von Kondo, Takeru, Okawa, Hiroko, Hokugo, Akishige, Shokeen, Bhumika, Sundberg, Oskar, Zheng, Yiying, McKenna, Charles E., Lux, Renate, Nishimura, Ichiro

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A Novel Osteogenic Oxysterol Compound for Therapeutic Development to Promote Bone Growth: Activation of Hedgehog Signaling and Osteogenesis Through Smoothened Binding von Montgomery, Scott R, Nargizyan, Taya, Meliton, Vicente, Nachtergaele, Sigrid, Rohatgi, Rajat, Stappenbeck, Frank, Jung, Michael E, Johnson, Jared S, Aghdasi, Bayan, Tian, Haijun, Weintraub, Gil, Inoue, Hirokazu, Atti, Elisa, Tetradis, Sotirios, Pereira, Renata C, Hokugo, Akishige, Alobaidaan, Raed, Tan, Yanlin, Hahn, Theodor J, Wang, Jeffrey C, Parhami, Farhad

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Preparation of hybrid scaffold from fibrin and biodegradable polymer fiber von Hokugo, Akishige, Takamoto, Tomoaki, Tabata, Yasuhiko

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In vitro assessment of Neuronal PAS domain 2 mitigating compounds for scarless wound healing von Clements, Adam, Shibuya, Yoichiro, Hokugo, Akishige, Brooks, Zachary, Roca, Yvonne, Kondo, Takeru, Nishimura, Ichiro, Jarrahy, Reza

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Small Cytoskeleton-Associated Molecule, Fibroblast Growth Factor Receptor 1 Oncogene Partner 2/Wound Inducible Transcript-3.0 (FGFR1OP2/wit3.0), Facilitates Fibroblast-Driven Wound... von Lin, Audrey, Hokugo, Akishige, Choi, Jae, Nishimura, Ichiro

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In Vitro Osteoinductive Effects of Hydroxycholesterol on Human Adipose-Derived Stem Cells Are Mediated through the Hedgehog Signaling Pathway von Yalom, Anisa, Hokugo, Akishige, Sorice, Sarah, Li, Andrew, Segovia Aguilar, Luis A., Zuk, Patricia, Jarrahy, Reza

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Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice von Okawa, Hiroko, Kondo, Takeru, Hokugo, Akishige, Cherian, Philip, Sundberg, Oskar, Campagna, Jesus J., Kashemirov, Boris A., John, Varghese, Sun, Shuting, Ebetino, Frank H., McKenna, Charles E., Nishimura, Ichiro

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47. Development of Dried Allogeneic Human Cultured Epidermis As a Wound Dressing: Evaluation of Healing Acceleration in Murine and Porcine Skin Defects von Nakano, Takashi, Sakamoto, Michiharu, Tsuge, Itaru, Yamanaka, Hiroki, Katayama, Yasuhiro, Shimizu, Yoshihiro, Note, Yoshika, Inoie, Masukazu, Hokugo, Akishige, Morimoto, Naoki

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Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery von Subbiah, Naren, Campagna, Jesus, Spilman, Patricia, Alam, Mohammad Parvez, Sharma, Shivani, Hokugo, Akishige, Nishimura, Ichiro, John, Varghese

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Wound closure and wound management: A new therapeutic molecular target von Lin, Audrey, Hokugo, Akishige, Nishimura, Ichiro

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