Targeting mitochondria for cancer therapy von Hockenbery, David M

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A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells von Procko, Erik, Berguig, Geoffrey Y., Shen, Betty W., Song, Yifan, Frayo, Shani, Convertine, Anthony J., Margineantu, Daciana, Booth, Garrett, Correia, Bruno E., Cheng, Yuanhua, Schief, William R., Hockenbery, David M., Press, Oliver W., Stoddard, Barry L., Stayton, Patrick S., Baker, David

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Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells von Delgado, Tracie, Carroll, Patrick A., Punjabi, Almira S., Margineantu, Daciana, Hockenbery, David M., Lagunoff, Michael, Roizman, Bernard

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Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development von Park, Heon, Staehling, Karen, Tsang, Mark, Appleby, Mark W., Brunkow, Mary E., Margineantu, Daciana, Hockenbery, David M., Habib, Tania, Liggitt, H. Denny, Carlson, George, Iritani, Brian M.

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Hsp90 inhibition decreases mitochondrial protein turnover von Margineantu, Daciana H, Emerson, Christine B, Diaz, Dolores, Hockenbery, David M

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The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition von Sperber, Henrik, Mathieu, Julie, Wang, Yuliang, Ferreccio, Amy, Hesson, Jennifer, Xu, Zhuojin, Fischer, Karin A., Devi, Arikketh, Detraux, Damien, Gu, Haiwei, Battle, Stephanie L., Showalter, Megan, Valensisi, Cristina, Bielas, Jason H., Ericson, Nolan G., Margaretha, Lilyana, Robitaille, Aaron M., Margineantu, Daciana, Fiehn, Oliver, Hockenbery, David, Blau, C. Anthony, Raftery, Daniel, Margolin, Adam A., Hawkins, R. David, Moon, Randall T., Ware, Carol B., Ruohola-Baker, Hannele

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Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease von Steinbach, Gideon, Hockenbery, David M, Huls, Gerwin, Furlong, Terry, Myerson, David, Loeb, Keith R, Fann, Jesse R, Castilla-Llorente, Christina, McDonald, George B, Martin, Paul J

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Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism von Iwata, Terri N, Ramírez, Julita A, Tsang, Mark, Park, Heon, Margineantu, Daciana H, Hockenbery, David M, Iritani, Brian M

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Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation von Centini, Ryan, Tsang, Mark, Iwata, Terri, Park, Heon, Delrow, Jeffrey, Margineantu, Daciana, Iritani, Brandon M, Gu, Haiwei, Liggitt, H Denny, Kang, Janella, Kang, Lim, Hockenbery, David M, Raftery, Daniel, Iritani, Brian M

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Mitochondrial diabetes in mice expressing a dominant-negative allele of nuclear respiratory factor-1 (Nrf1) in pancreatic β-cells von Morrish, Fionnuala, Gingras, Helene, Noonan, Joanna, Huang, Li, Sweet, Ian R., Kuok, Iok Teng, Knoblaugh, Sue E., Hockenbery, David M.

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Multimodal prediction of neoadjuvant treatment outcome by serial FDG PET and MRI in women with locally advanced breast cancer von Kazerouni, Anum S, Peterson, Lanell M, Jenkins, Isaac, Novakova-Jiresova, Alena, Linden, Hannah M, Gralow, Julie R, Hockenbery, David M, Mankoff, David A, Porter, Peggy L, Partridge, Savannah C, Specht, Jennifer M

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Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy von Reyes, Nicholas L., Banks, Glen B., Tsang, Mark, Margineantu, Daciana, Gu, Haiwei, Djukovic, Danijel, Chan, Jacky, Torres, Michelle, Liggitt, H. Denny, Hirenallur-S, Dinesh K., Hockenbery, David M., Raftery, Daniel, Iritani, Brian M.

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Mitochondrial functions in stem cells von Margineantu, Daciana H, Hockenbery, David M

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Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans von Lampe, Johanna W, Kim, Eunji, Levy, Lisa, Davidson, Laurie A, Goldsby, Jennifer S, Miles, Fayth L, Navarro, Sandi L, Randolph, Timothy W, Zhao, Ni, Ivanov, Ivan, Kaz, Andrew M, Damman, Christopher, Hockenbery, David M, Hullar, Meredith AJ, Chapkin, Robert S

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Inhibition of vaccinia virus replication by nitazoxanide von Hickson, Sarah E., Margineantu, Daciana, Hockenbery, David M., Simon, Julian A., Geballe, Adam P.

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Bcl-2 family proteins as regulators of oxidative stress von Susnow, Nathan, Zeng, Liyun, Margineantu, Daciana, Hockenbery, David M

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Activation of NF-κB by Palmitate in Endothelial Cells: A Key Role for NADPH Oxidase-Derived Superoxide in Response to TLR4 Activation von Maloney, Ezekiel, Sweet, Ian R, Hockenbery, David M, Pham, Matilda, Rizzo, Norma O, Tateya, Sanshiro, Handa, Priya, Schwartz, Michael W, Kim, Francis

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Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer von Berger, Stephanie, Procko, Erik, Margineantu, Daciana, Lee, Erinna F, Shen, Betty W, Zelter, Alex, Silva, Daniel-Adriano, Chawla, Kusum, Herold, Marco J, Garnier, Jean-Marc, Johnson, Richard, MacCoss, Michael J, Lessene, Guillaume, Davis, Trisha N, Stayton, Patrick S, Stoddard, Barry L, Fairlie, W Douglas, Hockenbery, David M, Baker, David

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Myc-dependent Mitochondrial Generation of Acetyl-CoA Contributes to Fatty Acid Biosynthesis and Histone Acetylation during Cell Cycle Entry von Morrish, Fionnuala, Noonan, Jhoanna, Perez-Olsen, Carissa, Gafken, Philip R., Fitzgibbon, Matthew, Kelleher, Joanne, VanGilst, Marc, Hockenbery, David

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Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism von Davis, Ryan J., Gönen, Mehmet, Margineantu, Daciana H., Handeli, Shlomo, Swanger, Jherek, Hoellerbauer, Pia, Paddison, Patrick J., Gu, Haiwei, Raftery, Daniel, Grim, Jonathan E., Hockenbery, David M., Margolin, Adam A., Clurman, Bruce E.

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