DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome von Richter, Hans, Satz, Alexander L, Bedoucha, Marc, Buettelmann, Bernd, Petersen, Ann C, Harmeier, Anja, Hermosilla, Ricardo, Hochstrasser, Remo, Burger, Dominique, Gsell, Bernard, Gasser, Rodolfo, Huber, Sylwia, Hug, Melanie N, Kocer, Buelent, Kuhn, Bernd, Ritter, Martin, Rudolph, Markus G, Weibel, Franziska, Molina-David, Judith, Kim, Jin-Ju, Santos, Javier Varona, Stihle, Martine, Georges, Guy J, Bonfil, R. Daniel, Fridman, Rafael, Uhles, Sabine, Moll, Solange, Faul, Christian, Fornoni, Alessia, Prunotto, Marco

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Discovery of 3‑Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors von Liu, Yongfu, Wu, Jun, Zhou, Mingwei, Chen, Wenming, Li, Dongbo, Wang, Zhanguo, Hornsperger, Benoit, Aebi, Johannes D, Märki, Hans-Peter, Kuhn, Bernd, Wang, Lisha, Kuglstatter, Andreas, Benz, Jörg, Müller, Stephan, Hochstrasser, Remo, Ottaviani, Giorgio, Xin, Jian, Kirchner, Stephan, Mohr, Susanne, Verry, Philippe, Riboulet, William, Shen, Hong C, Mayweg, Alexander V, Amrein, Kurt, Tan, Xuefei

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Novel potent and highly selective DDR1 inhibitors from integrated lead finding von Kuhn, Bernd, Ritter, Martin, Benz, Jörg, Kocer, Buelent, Sarie, Jérôme C., Hochstrasser, Remo, Rudolph, Markus G., Kadono, Shojiro, Matsuura, Tetsu, Murata, Takeshi, Richter, Hans, Prunotto, Marco

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Analysis of Current DNA Encoded Library Screening Data Indicates Higher False Negative Rates for Numerically Larger Libraries von Satz, Alexander L, Hochstrasser, Remo, Petersen, Ann C

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Development of a Highly Selective NanoBRET Probe to Assess MAGL Inhibition in Live Cells von Gazzi, Thais, Brennecke, Benjamin, Olikauskas, Valentas, Hochstrasser, Remo, Wang, Haiyan, Keen Chao, Suzan, Atz, Kenneth, Mostinski, Yelena, Topp, Andreas, Heer, Dominik, Kaufmann, Isabelle, Ritter, Martin, Gobbi, Luca, Hornsperger, Benoit, Wagner, Bjoern, Richter, Hans, O'Hara, Fionn, Wittwer, Matthias B, Jul Hansen, Dennis, Collin, Ludovic, Kuhn, Bernd, Benz, Joerg, Grether, Uwe, Nazaré, Marc

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Melting of a DNA helix terminus within the active site of a DNA polymerase von Hochstrasser, Remo A, Carver, Theodore E, Sowers, Lawrence C, Millar, David P

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β‑Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease von Hilpert, Hans, Guba, Wolfgang, Woltering, Thomas J, Wostl, Wolfgang, Pinard, Emmanuel, Mauser, Harald, Mayweg, Alexander V, Rogers-Evans, Mark, Humm, Roland, Krummenacher, Daniela, Muser, Thorsten, Schnider, Christian, Jacobsen, Helmut, Ozmen, Laurence, Bergadano, Alessandra, Banner, David W, Hochstrasser, Remo, Kuglstatter, Andreas, David-Pierson, Pascale, Fischer, Holger, Polara, Alessandra, Narquizian, Robert

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Seamless Integration of Dose-Response Screening and Flow Chemistry: Efficient Generation of Structure-Activity Relationship Data of β-Secretase (BACE1) Inhibitors von Werner, Michael, Kuratli, Christoph, Martin, Rainer E., Hochstrasser, Remo, Wechsler, David, Enderle, Thilo, Alanine, Alexander I., Vogel, Horst

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Discovery of Orally Available and Brain Penetrant AEP Inhibitors von Krummenacher, Daniela, He, Weiping, Kuhn, Bernd, Schnider, Christian, Beurier, Angélica, Brom, Virginie, Sivasothy, Thulase, Marty, Christine, Tosstorff, Andreas, Hewings, David S., Mesch, Stefanie, Pinard, Emmanuel, Brändlin, Mathis, Hochstrasser, Remo, Westwood, Paul, Rothe, Judith, Kronenberger, Alexandra, Morandi, Federica, Gutbier, Simon, Schuler, Angelika, Heer, Dominik, Gloria, Ludivine Esteves, Joedicke, Lisa, Rudolph, Markus G., Müller, Lutz, Grüninger, Fiona, Baumann, Karlheinz, Kaniyappan, Senthilvelrajan, Manevski, Nenad, Bartels, Björn

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Dynamics of mismatched base pairs in DNA von Guest, Christopher R, Hochstrasser, Remo A, Sowers, Lawrence C, Millar, David P

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SiLA: Basic Standards for Rapid Integration in Laboratory Automation von Bär, Henning, Hochstrasser, Remo, Papenfuß, Bernd

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Proofreading DNA: Recognition of Aberrant DNA Termini by the Klenow Fragment of DNA Polymerase I von Carver, Theodore E., Hochstrasser, Remo A., Millar, David P.

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Seamless Integration of Dose-Response Screening and Flow Chemistry: Efficient Generation of Structure-Activity Relationship Data of [beta]-Secretase (BACE1) Inhibitors von Werner, Michael, Kuratli, Christoph, Martin, Rainer E, Hochstrasser, Remo, Wechsler, David, Enderle, Thilo, Alanine, Alexander I, Vogel, Horst

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Inside Cover: Seamless Integration of Dose-Response Screening and Flow Chemistry: Efficient Generation of Structure-Activity Relationship Data of β-Secretase (BACE1) Inhibitors (An... von Werner, Michael, Kuratli, Christoph, Martin, Rainer E., Hochstrasser, Remo, Wechsler, David, Enderle, Thilo, Alanine, Alexander I., Vogel, Horst

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Inside Cover: Seamless Integration of Dose-Response Screening and Flow Chemistry: Efficient Generation of Structure-Activity Relationship Data of [beta]-Secretase (BACE1) Inhibitor... von Werner, Michael, Kuratli, Christoph, Martin, Rainer E, Hochstrasser, Remo, Wechsler, David, Enderle, Thilo, Alanine, Alexander I, Vogel, Horst

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Synthesis and biological evaluation of 3-aryltyramines as fragments binding to BACE-1 and BACE-2 von Fehler, Stefanie K., Pratsch, Gerald, Huber, Walter, Gast, Alain, Hochstrasser, Remo, Hennig, Michael, Heinrich, Markus R.

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Interaction of DNA with the Klenow fragment of DNA polymerase I studied by time-resolved fluorescence spectroscopy von Guest, Christopher R, Hochstrasser, Remo A, Allen, Dwayne J, Benkovic, Stephen J, Millar, David P, Dupuy, Charles G

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High-Resolution Capillary Tube NMR. A Miniaturized 5-μL High-Sensitivity TXI Probe for Mass-Limited Samples, Off-Line LC NMR, and HT NMR von Schlotterbeck, Götz, Ross, Alfred, Hochstrasser, Remo, Senn, Hans, Kühn, Till, Marek, Daniel, Schett, Oscar

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Biosensors in Biomedical Research: Development and Applications of Gene Chips von Certa, Ulrich, Hochstrasser, Remo, Langen, Hanno, Buess, Martin, Moroni, Christoph

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Characterization of amino acid side chain dynamics in a zinc-finger peptide using carbon-13 NMR spectroscopy and time-resolved fluorescence spectroscopy von Palmer, Arthur G, Hochstrasser, Remo A, Millar, David P, Rance, Mark, Wright, Peter E

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